Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Chenhui Zeng"'
Autor:
Lulu Liu, Xin Guo, Yao Wang, Guo Li, Yanyan Yu, Yang Song, Chenhui Zeng, Zhilou Ding, Yuanjun Qiu, Feifei Yan, Yi-Xiang Zhang, Caiqi Zhao, Yan Zhang, Yali Dou, Peter Atadja, En Li, He Wang
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1869(2)
WD repeat domain 5 (WDR5) is a prominent target for pharmacological inhibition in cancer through its scaffolding role with various oncogenic partners such as MLL and MYC. WDR5-related drug discovery efforts center on blocking these binding interfaces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb996863c9c992d83cfd9a845632fb4
https://pubmed.ncbi.nlm.nih.gov/36402263
https://pubmed.ncbi.nlm.nih.gov/36402263
Autor:
Mengxi Zhao, Xinjian Ge, Zhaofu Wang, Guobin Li, Qiong Zhang, Leying Feng, Ling Li, Peter Atadja, Long Wang, Justin Gu, Jue Zeng, Ho Man Chan, Jeff Zhang, Yanyan Yu, Kehao Zhao, Yuan Gao, Hailong Zhang, Fangjun Luo, Shaolian Zhou, Lijun Zhang, Ying Lin, Youzhen Wang, Counde Oyang, Lin Teng, Yueqin Liu, Chao Zhang, Lijian Feng, Minlong Shi, En Li, Chenhui Zeng, Qi Fei, Douglas Fang, Ying Huang, Hui Ge, Zhengtian Yu, Zijun Chen, Andreas Lingel, Shannon Chuai, Man Zhang, Wei Qi
Publikováno v:
Nature Chemical Biology. 13:381-388
Polycomb repressive complex 2 (PRC2) consists of three core subunits, EZH2, EED and SUZ12, and plays pivotal roles in transcriptional regulation. The catalytic subunit EZH2 methylates histone H3 lysine 27 (H3K27), and its activity is further enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400404226d3970f38cd2285d01a9eb26
https://doi.org/10.1038/nchembio.2304
https://doi.org/10.1038/nchembio.2304
Quantitative Profiling of Combinational K27/K36 Modifications on Histone H3 Variants in Mouse Organs
Autor:
Yanyan Yu, Yi Wang, Jiajia Chen, Rijing Liao, Yuan Gao, Hong Jin, Chenhui Zeng, Wei Yi, Shaolian Zhou, Pengyuan Yang, Jun Gao, En Li, Counde Oyang
Publikováno v:
Journal of Proteome Research. 15:1070-1079
The coexisting post-translational modifications (PTMs) on histone H3 N-terminal tails were known to crosstalk between each other, indicating their interdependency in the epigenetic regulation pathways. H3K36 methylation, an important activating mark,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9c2e40552b67ee7c757f364a8de081
https://doi.org/10.1021/acs.jproteome.5b01164
https://doi.org/10.1021/acs.jproteome.5b01164
Autor:
Jiang Shao, Chenhui Zeng
Publikováno v:
2018 Prognostics and System Health Management Conference (PHM-Chongqing).
In order to research the sinusoidal vibration reliability of plastic ball grid array (PBGA) solder joints, sinusoidal vibration tests on PBGA specimens were designed. The specimens were subjected to three kinds of different vibration excitations arou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5155944992f92189ca68bccfc64e0a50
https://doi.org/10.1109/phm-chongqing.2018.00198
https://doi.org/10.1109/phm-chongqing.2018.00198
Publikováno v:
2018 Annual Reliability and Maintainability Symposium (RAMS).
In this paper, the non-probabilistic reliability analysis method based on the finite elements mass change (FEMC) strategy is proposed. This method could conquer the difficulties caused by the strong nonlinearity of the material and geometry, and it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f80a2fd6d5af421e1e54de3f3ea56c1
https://doi.org/10.1109/ram.2018.8463011
https://doi.org/10.1109/ram.2018.8463011
Publikováno v:
Proceedings of the 2018 International Conference on Mechanical, Electrical, Electronic Engineering & Science (MEEES 2018).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::746f4e5219fe06ef47583da2f46f1f9b
https://doi.org/10.2991/meees-18.2018.86
https://doi.org/10.2991/meees-18.2018.86
Publikováno v:
2017 International Conference on Computer Systems, Electronics and Control (ICCSEC).
Hammering method modal testing has economic, convenient and efficient advantages, etc., which is widely used in the small structure modal analysis. However, the application scope is limited in the larger structure due to small excitation energy, weak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::596dff0028cedf840a3f16aa3303a26c
https://doi.org/10.1109/iccsec.2017.8446793
https://doi.org/10.1109/iccsec.2017.8446793
Publikováno v:
2017 IEEE International Conference on Industrial Engineering and Engineering Management (IEEM).
In two-level maintenance, the intermediate-level sites are replaced by other sites. How to allocated tasks of testing and replacing shop-replaced units is the key to balance material reliability and expenses. This paper raises basic maintenance unit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9541233256b8a507b99bc5cb546fc53b
https://doi.org/10.1109/ieem.2017.8290271
https://doi.org/10.1109/ieem.2017.8290271
Autor:
Jelena Klawitter, Andrea Hornberger, Chenhui Zeng, Stephan Bek, Touraj Shokati, Jost Klawitter, K. Olaf Boernsen, Richard Gilbert, Marjorie Zakaria, Uwe Christians
Publikováno v:
Analytical and Bioanalytical Chemistry. 406:6399-6408
Stearoyl-CoA desaturase 1 (SCD1) plays a role in the development of obesity and related conditions, such as insulin resistance, and potentially also in neurological and heart diseases. The activity of SCD1 can be monitored using the desaturation inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025f2a79db25917508c7a60c5ef876d4
https://doi.org/10.1007/s00216-014-8020-4
https://doi.org/10.1007/s00216-014-8020-4
Autor:
Peter Juhasz, Björn Glinghammar, Jonas Bäckström, Shunghuang Wang, Ina Schuppe-Koistinen, Lars I. Nord, Maritha Marcusson-Ståhl, Johan Kolmert, Raji Balasubramanian, Steve Martin, Chenhui Zeng, Ulf Andersson, Kerstin Nilsson, Karin Cederbrant, Mira Hannula, Johan Lindberg
Publikováno v:
Biomarkers. 14:572-586
Ximelagatran was developed for the prevention and treatment of thromboembolic conditions. However, in long-term clinical trials with ximelagatran, the liver injury marker, alanine aminotransferase (ALT) increased in some patients. Analysis of plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfcc57f4f7fc73438676a4dd7b2d318e
https://doi.org/10.3109/13547500903261354
https://doi.org/10.3109/13547500903261354