Výsledky vyhledávání - "Chenhaoyi Xu"

Akademický článek

No sex difference was found in the safety and efficacy of intravenous alteplase before endovascular therapy

Autor: Min Fang, Chenhaoyi Xu, Lan Ma, Yue Sun, Xiaoyu Zhou, Jiangshan Deng, Xueyuan Liu

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

Background and purposePrior studies on sex disparities were post-hoc analyses, had limited treatment modalities, and had controversial findings. Our study aimed to examine whether sex difference modifies the effect of intravenous alteplase before end

Externí odkaz: https://doaj.org/article/6a91d1f83c1e46908b51f74eb5f9354f

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Akademický článek

Transplantation of fecal microbiota from APP/PS1 mice and Alzheimer’s disease patients enhanced endoplasmic reticulum stress in the cerebral cortex of wild-type mice

Autor: Fang Wang, Yongzhe Gu, Chenhaoyi Xu, Kangshuai Du, Chence Zhao, Yanxin Zhao, Xueyuan Liu

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

Background and purposeThe gut-brain axis is bidirectional and the imbalance of the gut microbiota usually coexists with brain diseases, including Alzheimer’s disease (AD). Accumulating evidence indicates that endoplasmic reticulum (ER) stress is a

Externí odkaz: https://doaj.org/article/4b2e8a346e9948b29d57991246cf1e75

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Akademický článek

Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyladenosine Modification

Autor: Chenhaoyi Xu, Huanghuang Huang, Min Zhang, Pei Zhang, Zezhi Li, Xueyuan Liu, Min Fang

Publikováno v: Frontiers in Aging Neuroscience, Vol 14 (2022)

Activity-regulated cytoskeleton-associated protein (ARC) is activated by the induction of long-term potentiation and plays an important role in the synaptic plasticity of memory consolidation. Previous studies have shown that abnormal expression of A

Externí odkaz: https://doaj.org/article/eaaf45b6a89f4614954bc8c013a44a50

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Repressor element-1 silencing transcription factor regulates glutamate receptors and immediate early genes to affect synaptic plasticity

Autor: Lu Zu, Xueyuan Liu, Min Zhang, Chenhaoyi Xu, Letao Sun, Pei Zhang, Min Fang

Publikováno v: Aging (Albany NY)

Objective This study aimed to investigate the regulatory effects of repressor element-1 silencing transcription factor (REST) on the glutamate receptors and immediate early genes (IEGs) in the SH-SY5Y cells. Methods The genes regulated by REST were s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102bf9091f682a0116dd3b91723a807f
http://europepmc.org/articles/PMC8221361

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Neurofilament Light Chain (NF-L) Stimulates Lipid Peroxidation to Neuronal Membrane through Microglia-Derived Ferritin Heavy Chain (FTH) Secretion

Autor: Li Gong, Qiuyue Yu, Haichao Wang, Chenhaoyi Xu, Yunxiao Dou, Bingjie Mao, Yanxin Zhao

Publikováno v: Oxidative medicine and cellular longevity. 2022

A part of the axonal cytoskeleton protein complex, neurofilament light chain (NF-L) has been suggested as a pathological hallmark in various neurological disorders, including hemorrhagic stroke, vascular dementia, and cerebral small vessel disease. N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2a49482fb272a112860cfc1aa69507
https://pubmed.ncbi.nlm.nih.gov/35368870

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