Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Chengzhu Zhao"'
Autor:
Chengzhu Zhao, Makoto Ikeya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibro/adipogenic progenitors (FAPs) that reside in muscle tissue are crucial for muscular homeostasis and regeneration as they secrete signaling molecules and components of the extracellular matrix. During injury or disease, FAPs differentiate into d
Externí odkaz:
https://doaj.org/article/01dc4e49159d4b23aa69dd8bb338f738
Autor:
Qiuling Guo, Jingjing Chen, Qiqi Bu, Jinling Zhang, Minjie Ruan, Xiaoyu Chen, Mingming Zhao, Xiaolin Tu, Chengzhu Zhao
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101111- (2024)
Human induced pluripotent stem cell (hiPSC)-derived mesenchymal stem cells (iMSCs) are ideal candidates for the production of standardised and scalable bioengineered bone grafts. However, stable induction and osteogenic differentiation of iMSCs pose
Externí odkaz:
https://doaj.org/article/ef882ee943ac4dd29fc0512eeb56ca7a
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Enrichment of Veillonella parvula in the lung microbiota is strongly associated with non-small cell lung cancer (NSCLC) and induces the progression of lung adenocarcinoma in vivo, but its actual role and mechanism remain unexplored. This stu
Externí odkaz:
https://doaj.org/article/4b29378cbfe34e9ea2d6de2784bdd347
Autor:
Chengzhu Zhao, Yoshiko Inada, Kazuya Sekiguchi, Kyosuke Hino, Megumi Nishio, Yasuhiro Yamada, Shuichi Matsuda, Junya Toguchida, Makoto Ikeya
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 731-734 (2023)
Externí odkaz:
https://doaj.org/article/95ba83ae53fe4a348c39f507484b9713
Autor:
Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai, Hidemi Kurihara, Makoto Ikeya
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-17 (2022)
Abstract Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) lineage under xeno-free conditions and evaluated their in vivo func
Externí odkaz:
https://doaj.org/article/4f3d037871344649b4422fc8b516e401
Autor:
Keisuke Mizuno, Hiroe Ohnishi, Masayoshi Yoshimatsu, Chengzhu Zhao, Yasuyuki Hayashi, Fumihiko Kuwata, Shinji Kaba, Hideaki Okuyama, Yoshitaka Kawai, Nao Hiwatashi, Yo Kishimoto, Tatsunori Sakamoto, Makoto Ikeya, Koichi Omori
Publikováno v:
Cell Transplantation, Vol 32 (2023)
Previous studies transplanted human-induced pluripotent stem cells (hiPSCs)-derived mesenchymal stem cells (iMSCs) into thyroid cartilage defect of X-liked severe combined immunodeficiency (X-SCID) rats and confirmed transplanted cell survival and ca
Externí odkaz:
https://doaj.org/article/8e0be10c404e40329e596f7bb5e3e1c6
Autor:
Denise Zujur, Ziadoon Al-Akashi, Anna Nakamura, Chengzhu Zhao, Kazuma Takahashi, Shizuka Aritomi, William Theoputra, Daisuke Kamiya, Koichi Nakayama, Makoto Ikeya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: To date, there is no effective long-lasting treatment for cartilage tissue repair. Primary chondrocytes and mesenchymal stem/stromal cells are the most commonly used cell sources in regenerative medicine. However, both cell types have lim
Externí odkaz:
https://doaj.org/article/e0af63184c45470983c411e103e08cd7
Autor:
Taiki Nakajima, Akihiro Nakahata, Naoki Yamada, Keiko Yoshizawa, Tomoaki M. Kato, Mio Iwasaki, Chengzhu Zhao, Hiroshi Kuroki, Makoto Ikeya
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Tendon self-renewal occurs rarely and reconstructive surgery comes with significant limitations. Here the authors present an induced pluripotent stem cell-based method to generate tenocytes, analyze their developmental trajectory using scRNA-seq, and
Externí odkaz:
https://doaj.org/article/a931afc1a44f40fc91158434225321bb
Autor:
Masayoshi Yoshimatsu, Hiroe Ohnishi, Chengzhu Zhao, Yasuyuki Hayashi, Fumihiko Kuwata, Shinji Kaba, Hideaki Okuyama, Yoshitaka Kawai, Nao Hiwatashi, Yo Kishimoto, Tatsunori Sakamoto, Makoto Ikeya, Koichi Omori
Publikováno v:
Stem Cell Research, Vol 52, Iss , Pp 102233- (2021)
The laryngotracheal cartilage is a cardinal framework for the maintenance of the airway for breathing, which occasionally requires reconstruction. Because hyaline cartilage has a poor intrinsic regenerative ability, various regenerative approaches ha
Externí odkaz:
https://doaj.org/article/c8c1e68581084b458d06102e5504a7ab
Autor:
Kyosuke Hino, Chengzhu Zhao, Kazuhiko Horigome, Megumi Nishio, Yasue Okanishi, Sanae Nagata, Shingo Komura, Yasuhiro Yamada, Junya Toguchida, Akira Ohta, Makoto Ikeya
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1106-1119 (2018)
Summary: Fibrodysplasia ossificans progressiva (FOP) is a rare and intractable disorder characterized by extraskeletal bone formation through endochondral ossification. FOP patients harbor gain-of-function mutations in ACVR1 (FOP-ACVR1), a type I rec
Externí odkaz:
https://doaj.org/article/6fad6a02adfe4b8eb25a135199479482