Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Chengzhong Xing"'
Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases
Autor:
Jingwei Liu, Yutong Xiao, Liangzi Cao, Songming Lu, Siyi Zhang, Ruohan Yang, Yubang Wang, Naijin Zhang, Yang Yu, Xiwen Wang, Wendong Guo, Zhuo Wang, Hongde Xu, Chengzhong Xing, Xiaoyu Song, Liu Cao
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Autophagy is a dynamic self-renovation biological process that maintains cell homeostasis and is responsible for the quality control of proteins, organelles, and energy metabolism. The E1-like ubiquitin-activating enzyme autophagy-related ge
Externí odkaz:
https://doaj.org/article/1262af08769642d2aaf8051d14db5b0a
Autor:
Jingwei Liu, Liangzi Cao, Yubang Wang, Yu Zou, Qiqiang Guo, Shu Chen, Bo Jiang, Xuan Wu, Lixia Zheng, Siyi Zhang, Songming Lu, Keshen Zhou, Pengcheng Jiang, Yutong Xiao, Ruohan Yang, Shiyuan Dong, Ziwei Li, Di Chen, Ying Zhang, Naijin Zhang, Guozhe Sun, Chengzhong Xing, Xiaoyu Song, Zhenning Wang, Liu Cao
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114366- (2024)
Summary: p53 regulates multiple signaling pathways and maintains cell homeostasis under conditions of DNA damage and oxidative stress. Although USP7 has been shown to promote p53 stability via deubiquitination, the USP7-p53 activation mechanism has r
Externí odkaz:
https://doaj.org/article/d065b697ade3469dbcfa880c2b16d7fd
Autor:
Liangzi Cao, Hao Li, Xiaofang Liu, Yubang Wang, Bowen Zheng, Chengzhong Xing, Naijin Zhang, Jingwei Liu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract NEDD4 family represent an important group of E3 ligases, which regulate various cellular pathways of cell proliferation, cell junction and inflammation. Emerging evidence suggested that NEDD4 family members participate in the initiation and
Externí odkaz:
https://doaj.org/article/b2faf3b0e8b64bd39fe23e91ec58b35e
Autor:
Jingwei Liu, Songming Lu, Lixia Zheng, Qiqiang Guo, Liangzi Cao, Yutong Xiao, Di Chen, Yu Zou, Xu Liu, Chengsi Deng, Siyi Zhang, Ruohan Yang, Yubang Wang, Ying Zhang, Naijin Zhang, Xiaoyu Song, Chengzhong Xing, Zhenning Wang, Liu Cao
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113402- (2023)
Summary: Oxidative stress-induced autophagy helps to prevent cellular damage and to maintain homeostasis. However, the regulatory pathway that initiates autophagy remains unclear. We previously showed that reactive oxygen species (ROS) function as si
Externí odkaz:
https://doaj.org/article/a187fb4415c04841bc8ee9e30036269a
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Ubiquitination is a critical type of post-translational modifications, of which K63-linked ubiquitination regulates interaction, translocation, and activation of proteins. In recent years, emerging evidence suggest involvement of K63-linked
Externí odkaz:
https://doaj.org/article/567695090a154965bca0c89cf6da31fe
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background XPF (xeroderma pigmentosum complementation group F) is a key factor contributing to DNA damage excision of nucleotide excision repair pathway. The relationship between XPF expression and the risk and prognosis of colorectal cancer
Externí odkaz:
https://doaj.org/article/dce33ba55606412383de60fe251f902e
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background N 6-methyladenosine (m6A) modification might be closely associated with the genesis and development of gastric cancer (GC). Currently, the evidence established by high-throughput assay for GC-related m6A patterns based on long non
Externí odkaz:
https://doaj.org/article/0279c32c24e543bfbc452699eb0d9602
Publikováno v:
IEEE Access, Vol 8, Pp 114916-114929 (2020)
Based on complex networks and machine learning methods, this paper studies the mining of colorectal cancer treatment genes, and innovatively combines a variety of feature extraction and comparative analysis methods, from gene network features, gene a
Externí odkaz:
https://doaj.org/article/2f518f62e7df4b5eac8f7b52de062d61
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Background: Dysregulated expression of TRIB3 and FABP1 have been previously observed in human cancer tissues. However, there are little information as to their expression change in dynamic gastric diseases and the functional roles.Methods: Tissues fr
Externí odkaz:
https://doaj.org/article/53ce2253ce61432189b5b6a890b73b5f
Publikováno v:
PeerJ, Vol 9, p e12647 (2021)
Objective ERCC4 is one of the most significant molecules of Nucleotide Excision Repair (NER), which has been researched due to its high expression in colorectal cancer (CRC). This study aimed to find out the ceRNA (competitive endogenous RNA) network
Externí odkaz:
https://doaj.org/article/23208fb70f804f6ab5a7d3f99fd3deef