Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chengyi J Shu"'
Autor:
Amanda Hanson, Kutlu Elpek, Ellen Duong, Lindsey Shallberg, Martin Fan, Calvin Johnson, Matthew Wallace, George R Mabry, Stephen Sazinsky, Lauren Pepper, Chengyi J Shu, Sriram Sathyanarayanan, Sarah Zuerndorfer, Tyler Simpson, Monica Gostissa, Michael Briskin, Deborah Law, Jennifer Michaelson, Christopher J Harvey
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239595 (2020)
Immunotherapy checkpoint inhibitors, such as antibodies targeting PD-1 and CTLA-4, have demonstrated the potential of harnessing the immune system to treat cancer. However, despite encouraging results particularly with respect to survival, only a min
Externí odkaz:
https://doaj.org/article/12342d258a3a4c9696b7dad685961d58
Autor:
Hongyue Dai, Shan Lou, Yanbo Zhang, Monica Thanawala, Kai‐Chih Huang, Lexiang Ji, Sarah Carden, Tiffany Liao, Mandana Abbassi, Chengyi J. Shu, Alexandra Lantermann, Masoud Sadaghiani, Daniel Blom, John Wagner, Pearl Huang
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 1, Pp 76-89 (2022)
Abstract Tumor innervation has recently been documented and characterized in various settings and tumor types. However, the role that nerves innervating tumors play in the pathogenesis of cancer has not been clarified. In this study, we searched for
Externí odkaz:
https://doaj.org/article/0e0fcf6304ed4f279d36259b70fff502
Autor:
Chengyi J. Shu, Shan Lou, Lexiang Ji, Hongyue Dai, Alexandra Lantermann, Masoud Sadaghiani, Yanbo Zhang, Tiffany Liao, Monica Thanawala, Pearl S. Huang, Daniel Blom, Kai-Chih Huang, Mandana Abbassi, John A. Wagner, Sarah Carden
Publikováno v:
FASEB BioAdvances
FASEB BioAdvances, Vol 4, Iss 1, Pp 76-89 (2022)
FASEB BioAdvances, Vol 4, Iss 1, Pp 76-89 (2022)
Tumor innervation has recently been documented and characterized in various settings and tumor types. However, the role that nerves innervating tumors play in the pathogenesis of cancer has not been clarified. In this study, we searched for neural si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d0acb51057f391cfc8fe5a880256ca
http://europepmc.org/articles/PMC8728105
http://europepmc.org/articles/PMC8728105
Autor:
Sini Thomas, Clifford J. Woolf, Katiane Roversi, Mohammad Balood, Mahdi Ahmadi, Alexandre Parrin, Chengyi J. Shu, Simmie L. Foster, Tuany Eichwald, Chih-Chieh Wang, Paola D. Vermeer, Ronny Drapkin, Sébastien Talbot, Monica Thanawala, Moutih Rafei, Daniel W. Vermeer, Sonia del Rincon, Corey R. Seehus, Alexandra Latini, Jacques Thibodeau, Manu Rangachari, Hannah Merrison, Abdelilah Majdoubi, Benjamin Doyle
Publikováno v:
SSRN Electronic Journal.
Tumor denervation limits cancer growth, but the mechanisms behind this are unknown. We find that malignant melanoma cells interact with pain-initiating nociceptor neurons by increasing neurite outgrowth, responsiveness to noxious ligands and neuropep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e42827153f841a40e63a04ff9bc5d721
https://doi.org/10.2139/ssrn.3571293
https://doi.org/10.2139/ssrn.3571293
Autor:
George Robert Mabry, Christopher Harvey, Matthew Wallace, Ellen Duong, Lauren Pepper, Michael Briskin, Jennifer S. Michaelson, Calvin Johnson, Kutlu G. Elpek, Amanda Hanson, Martin Fan, Tyler R. Simpson, Deborah Law, Monica Gostissa, Sarah Zuerndorfer, Lindsey Shallberg, Stephen Sazinsky, Chengyi J. Shu, Sriram Sathyanarayanan
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239595 (2020)
PLoS ONE
PLoS ONE
Immunotherapy checkpoint inhibitors, such as antibodies targeting PD-1 and CTLA-4, have demonstrated the potential of harnessing the immune system to treat cancer. However, despite encouraging results particularly with respect to survival, only a min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bc9d9f19bc5853a9bc59f25e18b14a
https://doi.org/10.1371/journal.pone.0239595
https://doi.org/10.1371/journal.pone.0239595
Autor:
Nagichettiar Satyamurthy, Owen N. Witte, Jason T. Lee, Michael E. Phelps, Chengyi J. Shu, Johannes Czernin, Caius G. Radu, Dean O. Campbell, Jordan Wengrod, Andrew Q. Tran
Publikováno v:
Journal of Nuclear Medicine. 51:1092-1098
Deoxycytidine kinase (dCK) is a rate-limiting enzyme in the deoxyribonucleoside salvage pathway and a critical determinant of therapeutic activity for several nucleoside analog prodrugs. We have previously reported the development of 1-(2′-deoxy-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52dcbfb8f725cc63fee8ee37ef46fdb0
https://doi.org/10.2967/jnumed.109.073361
https://doi.org/10.2967/jnumed.109.073361
Autor:
Michael E. Phelps, Nagichettiar Satyamurthy, Owen N. Witte, Evan Nair-Gill, Chengyi J. Shu, Caius G. Radu, Jorge R. Barrio, Stephanie M. Shelly
Publikováno v:
Nature medicine
Monitoring immune function with molecular imaging could have a considerable impact on the diagnosis and treatment evaluation of immunological disorders and therapeutic immune responses. Positron emission tomography (PET) is a molecular imaging modali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23e914d2c064e64e6257b57306ef821
http://europepmc.org/articles/PMC2720060
http://europepmc.org/articles/PMC2720060
Autor:
Antoni Ribas, Caius G. Radu, Haumith Khan-Farooqi, Muh-Shi Lin, Stephanie M. Shelly, Linda M. Liau, Chengyi J. Shu, Meng Yin Yang, Horacio Soto, Owen N. Witte, Robert M. Prins, Dan D. Vo
Publikováno v:
Cancer Immunology, Immunotherapy. 57:1279-1289
It is commonly believed that T cells have difficulty reaching tumors located in the brain due to the presumed "immune privilege" of the central nervous system (CNS). Therefore, we studied the biodistribution and anti-tumor activity of adoptively tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3b8e740a686445da86772db5df7dbb
https://doi.org/10.1007/s00262-008-0461-1
https://doi.org/10.1007/s00262-008-0461-1
Publikováno v:
Immunological Reviews. 221:214-228
Non-invasive monitoring of adaptive immunity in infection, cancer, and autoimmunity remains a major challenge. Current techniques to monitor lymphocytes involve numeric and functional determinations of immune cells isolated from the peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd7541c2b3cc2f491ff7f7ef07f9ed5
https://doi.org/10.1111/j.1600-065x.2008.00585.x
https://doi.org/10.1111/j.1600-065x.2008.00585.x
Publikováno v:
Trends in Biochemical Sciences. 28:121-124
A nitrate- and nitrite-sensing (NIT) domain as found in the NasR protein, has been detected in various receptor components of signal transduction pathways in different bacterial lineages. Cellular functions controlled by receptors that contain this n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403451309df3a3d27d7a1f69ee67bfb2
https://doi.org/10.1016/s0968-0004(03)00032-x
https://doi.org/10.1016/s0968-0004(03)00032-x