Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Chengyan Chu"'
Autor:
Leitao Zhang, Chengyan Chu, Xuefeng Lin, Rui Sun, Zibo Li, Sijia Chen, Yinqiao Liu, Jian Wu, Zhiqiang Yu, Xiqiang Liu
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract The fluorophores in the second near‐infrared (NIR‐II) biological window (1000 – 1700 nm) show great application prospects in the fields of biology and optical communications. However, both excellent radiative transition and nonradiativ
Externí odkaz:
https://doaj.org/article/ecf00cc706c1487fad550e42f98aeacf
Autor:
Aline M. Thomas, Ethan Yang, Matthew D. Smith, Chengyan Chu, Peter A. Calabresi, Kristine Glunde, Peter C. M. van Zijl, Jeff W. M. Bulte
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Multiple sclerosis (MS) is a neurodegenerative disease, wherein aberrant immune cells target myelin-ensheathed nerves. Conventional magnetic resonance imaging (MRI) can be performed to monitor damage to the central nervous system
Externí odkaz:
https://doaj.org/article/64f52c6b37a84bc98de8519ab2b2d3fa
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular diseases primarily affecting small arteries, capillaries, arterioles and venules. The diagnosis of CSVD relies on the identification of small subcortical infarcts, l
Externí odkaz:
https://doaj.org/article/a595c474296644549091db01de398572
Autor:
Rui Wang, Chengyan Chu, Zhiliang Wei, Lin Chen, Jiadi Xu, Yajie Liang, Miroslaw Janowski, Robert D. Stevens, Piotr Walczak
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Cell transplantation-based treatments for neurological disease are promising, yet graft rejection remains a major barrier to successful regenerative therapies. Our group and others have shown that long-lasting tolerance of transpl
Externí odkaz:
https://doaj.org/article/46b259a4337b422788c1b17cbe55e20c
Autor:
Jing Liu, Chengyan Chu, Jia Zhang, Chongxue Bie, Lin Chen, Safiya Aafreen, Jiadi Xu, David O. Kamson, Peter C. M. van Zijl, Piotr Walczak, Miroslaw Janowski, Guanshu Liu
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2529 (2022)
Purpose: Mannitol is a hyperosmolar agent for reducing intracranial pressure and inducing osmotic blood–brain barrier opening (OBBBO). There is a great clinical need for a non-invasive method to optimize the safety of mannitol dosing. The aim of th
Externí odkaz:
https://doaj.org/article/1bd9b26ce51345b39c9ab4dc645ca6df
Autor:
Xiaoyan Lan, Dorota A. Kedziorek, Chengyan Chu, Anna Jablonska, Shen Li, Mihoko Kai, Yajie Liang, Miroslaw Janowski, Piotr Walczak
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Currently, human glioma tumors are mostly modeled in immunodeficient recipients; however, lack of interactions with adaptive immune system is a serious flaw, particularly in the era when immunotherapies dominate treatment strategies. Our group was th
Externí odkaz:
https://doaj.org/article/3d71a26739f24d6aa4b62d4f4b1ebb7b
Publikováno v:
Membranes, Vol 11, Iss 7, p 484 (2021)
Rapidly ageing populations are beset by tissue wear and damage. Stem cell-based regenerative medicine is considered a solution. Years of research point to two important aspects: (1) the use of cellular imaging to achieve sufficient precision of thera
Externí odkaz:
https://doaj.org/article/ec4d23fb1ef14808837ab25975b66c50
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Ischemic stroke is a major cause of disability and mortality worldwide, but effective restorative treatments are very limited at present. Regenerative medicine research revealed that stem cells are promising therapeutic options. Dental pulp stem cell
Externí odkaz:
https://doaj.org/article/095006b6af8e4e1a98b82d1aff80c31b
Autor:
Chengyan Chu, Guanshu Liu, Miroslaw Janowski, Jeff W. M. Bulte, Shen Li, Monica Pearl, Piotr Walczak
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
The blood-brain barrier (BBB) prevents effective delivery of most therapeutic agents to the brain. Intra-arterial (IA) infusion of hyperosmotic mannitol has been widely used to open the BBB and improve parenchymal targeting, but the extent of BBB dis
Externí odkaz:
https://doaj.org/article/0784f14b663a426d80c33243c76535e7
Autor:
Chengyan Chu, Anna Jablonska, Yue Gao, Xiaoyan Lan, Wojciech G. Lesniak, Yajie Liang, Guanshu Liu, Shen Li, Tim Magnus, Monica Pearl, Miroslaw Janowski, Piotr Walczak
Publikováno v:
Nat Protoc
The blood–brain barrier (BBB) is the main obstacle to the effective delivery of therapeutic agents to the brain, compromising treatment efficacy for a variety of neurological disorders. Intra-arterial (IA) injection of hyperosmotic mannitol has bee