Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chengxin, Gu"'
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Objective This study aims to build a prognostic model of hepatocellular carcinoma (HCC) with ferroptosis-associated genes and explore their molecular function. Methods Gene expression data and clinical information were obtained from the Gene
Externí odkaz:
https://doaj.org/article/1c0a7c5f5fe2432e9cb8435466f2bf23
Autor:
Kunyuan Wang, Chengxin Gu, Ganxiang Yu, Jiaen Lin, Zhilei Wang, Qianting Lu, Yangzhi Xu, Dan Zhao, Xiaofeng Jiang, Weijian Mai, Shiming Liu, Hui Yang
Publikováno v:
Liver Research, Vol 6, Iss 3, Pp 167-174 (2022)
Background and aims: Berberine is one of the most promising clinically tested natural alkaloids, and immunotherapy using natural killer (NK) cells is a potentially effective treatment for hepatocellular carcinoma (HCC). This study aims to elucidate t
Externí odkaz:
https://doaj.org/article/d6bbe99e06b3491b82e53f6ecbc13871
Autor:
Kunyuan Wang, Ganxiang Yu, Jiaen Lin, Zhilei Wang, Qianting Lu, Chengxin Gu, Tao Yang, Shiming Liu, Hui Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Regorafenib resistance is a key limiting factor in the treatment of advanced hepatocellular carcinoma (HCC). Increasing evidence has demonstrated that Berberine (BBR) can synergistically enhance the therapeutic effect of various chemotherapeutic agen
Externí odkaz:
https://doaj.org/article/771360ed620c46c9b586ce3f6eaedfb1
Autor:
Weijian Mai, Yangzhi Xu, Jiahui Xu, Dan Zhao, Liangying Ye, Ganxiang Yu, Zhilei Wang, Qianting Lu, Jiaen Lin, Tao Yang, Chengxin Gu, Shiming Liu, Yun Zhong, Hui Yang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Berberine (BBR), an isoquinoline alkaloid originating from herbal plants, has been deemed beneficial for non-alcoholic fatty liver disease. Increasing evidence has demonstrated that Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammas
Externí odkaz:
https://doaj.org/article/3afd6b9b53094ba39f9c18f9004ef6b8
Autor:
Xingtian Chen, Yangzhi Xu, Dan Zhao, Ting Chen, Chengxin Gu, Ganxiang Yu, Ken Chen, Yun Zhong, Jie He, Shiming Liu, Yuqiang Nie, Hui Yang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Instances of obesity and related metabolic abnormalities are increasing across the world. Non-alcoholic fatty liver disease (NAFLD) is a common disorder in obese people and is becoming the leading cause of hepatocellular carcinoma. Recently, long non
Externí odkaz:
https://doaj.org/article/ec80fbc624254b9bbc872c937fdd9976
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Long non-coding RNAs (lncRNAs) have been implicated in liver carcinogenesis. We previously showed that the induction of lncRNA-uc002mbe.2 is positively associated with the apoptotic effect of trichostatin A (TSA) in hepatocellular carcinoma (HCC) cel
Externí odkaz:
https://doaj.org/article/b860f6df255245348b88c3c1036b4f82
Autor:
Shiming Liu, Jiaen Lin, Hui Yang, Kunyuan Wang, Chengxin Gu, Qianting Lu, Tao Yang, Ganxiang Yu, Zhilei Wang
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Regorafenib resistance is a key limiting factor in the treatment of advanced hepatocellular carcinoma (HCC). Increasing evidence has demonstrated that Berberine (BBR) can synergistically enhance the therapeutic effect of various chemotherapeutic agen
Autor:
Yun Zhong, Yuqiang Nie, Hui Yang, Chengxin Gu, Cailin Xue, Xiaofeng Jiang, Kunyuan Wang, Yongjian Zhou, Ganxiang Yu, Shiming Liu
Publikováno v:
Journal of Cancer
The suppressor of zest 12 (SUZ12), an essential subunit of the transcription polycomb repressive complex 2 (PRC2), has been found to be involved in HBV X-induced oncogenic transformation in hepatocellular carcinoma (HCC). However, the specific functi
Autor:
Ganxiang Yu, Dan Zhao, Yangzhi Xu, Zhilei Wang, Hui Yang, Jiyuan Zhou, Xiaofeng Jiang, Qianting Lu, Chengxin Gu, Shiming Liu, Kunyuan Wang, Jiaen Lin
Berberine (BBR) is an isoquinoline alkaloid with various functions in anti-inflammation, blocking tumor immune escape and enhancing the anti-tumor activity of immune cells. However, its immunomodulatory effect on natural killer (NK) cell activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adc26b19ace522d1cc4078ddced62936
https://doi.org/10.21203/rs.3.rs-353093/v1
https://doi.org/10.21203/rs.3.rs-353093/v1
Autor:
Hui Yang, Chengxin Gu, Yating Lang, Xinrui Wang, Zhilei Wang, Yanqin Wu, Kunyuan Wang, Xifei Zhu, Xiaoqin Wu
Publikováno v:
Medical Oncology. 36
The development of drug resistance affecting the prognosis of patients with hepatocellular carcinoma (HCC) leads to low survival rate of HCC patients. Caffeine is reported to have a function of protecting the liver and anti-tumor activity. Therefore,