Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Chengxian Guo"'
Autor:
Biwen Hu, Ling Ye, Tong Li, Zeying Feng, Longjian Huang, Chengjun Guo, Li He, Wei Tan, Guoping Yang, Zhiling Li, Chengxian Guo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Drug-induced acute kidney injury (DIKI) is a common adverse drug reaction event but is less known in pediatric patients. The study explored the DIKI in Chinese pediatric patients using the Pediatric Intensive Care database (PIC).Method: W
Externí odkaz:
https://doaj.org/article/7a96489210c6485a816115af30f5c0bc
Autor:
Yun Kuang, Yaxin Liu, Qi Pei, Xiaoyi Ning, Yi Zou, Liming Liu, Long Song, Chengxian Guo, Yuanyuan Sun, Kunhong Deng, Chan Zou, Dongsheng Cao, Yimin Cui, Chengkun Wu, Guoping Yang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundWarfarin is an effective treatment for thromboembolic disease but has a narrow therapeutic index, and dosage can differ tremendously among individuals. The study aimed to develop an individualized international normalized ratio (INR) model
Externí odkaz:
https://doaj.org/article/878d716558734f17bb677d55d21f1469
Autor:
Shanshan Nie, Kaifeng Chen, Chengxian Guo, Qi Pei, Chan Zou, Liangyuan Yao, Hongbo Yuan, Xia Zhao, Ran Xie, Xu He, Jie Huang, Guoping Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Background: Ticagrelor belongs to a new class of P2Y12 receptor inhibitor that has been widely used for antiplatelet therapy. This study aimed to explore the effect of single nucleotide polymorphisms (SNPs) in metabolic enzymes, transporters, and oth
Externí odkaz:
https://doaj.org/article/9a5c6bf707c54c3ebd09a71bf48dc349
Autor:
Shaojun Chen, Li Hua, Chengjun Feng, Qia Mo, Mengzhuan Wei, Yongqi Shen, Zhan Lin, Guisheng Li, Junyi Xu, Chengxian Guo, Haixin Huang
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background There are obviously ethnic differences between the UGT1A1 gene polymorphisms. Due to the difference of genetic background and environment, the treatment with colorectal cancer patients of Guangxi Zhuang should not completely follo
Externí odkaz:
https://doaj.org/article/4bd33fddaf58486cb65e3b908b54e9e9
Autor:
Xiaoxue Xie, Shenglan Gong, Hekun Jin, Pei Yang, Ting Xu, Yilong Cai, Chengxian Guo, Rong Zhang, Fan Lou, Wenjuan Yang, Hui Wang
Publikováno v:
Radiation Oncology, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background and purpose We evaluated the relationship between patient-, tumor-, and treatment-related features and radiation-induced lymphopenia (RIL) and evaluated the correlation between RIL and survival outcome in NPC patients to help impr
Externí odkaz:
https://doaj.org/article/04d6ad55df67445ab7d12d79231ecde8
Autor:
Chengxian Guo, Biwen Hu, Chengjun Guo, Xiangguang Meng, Yun Kuang, Longjian Huang, Danling Wang, Kangwei Xu, Yanlin Zhao, Guoping Yang, Weimin Cai, Yan Shu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
To elucidate current domestic factors influencing pharmacogenomics (PGx) implementation and its future in China, we conducted a questionnaire survey on PGx applications and testing. A questionnaire-based survey was created on the popular online profe
Externí odkaz:
https://doaj.org/article/185107d454644d71b9cec556f77844ee
Autor:
Zhijun Huang, Mengyao Wang, Li Liu, Jinfu Peng, Chengxian Guo, Xiaoping Chen, Lu Huang, Jieqiong Tan, Guoping Yang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Hepatic cytochrome P450 enzyme activities correlate with non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis. The decreased activity of CYP3A4, an important drug-metabolizing enzyme, is associated with the progression of NAFLD. CYP3A4 is
Externí odkaz:
https://doaj.org/article/8dfeb4ebee6e439a94b81c004deaec29
Autor:
Haigang Li, Yu Jiang, Yang Wang, Huiying Lv, Haitang Xie, Guoping Yang, Chengxian Guo, Jing Tang, Tao Tang
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The aim of this study was to elucidate the effects of warfarin on senkyunolide I in a rat model of biliary drainage after oral administration Chuanxiong extract based on pharmacokinetics. Thirty-two rats were randomly divided into four groups: CN, he
Externí odkaz:
https://doaj.org/article/5b94c73e961b487b9aab8097ee20d1ae
Autor:
Chengxiao Fu, Qi Pei, Wu Liang, Bo Yang, Wei Li, Jun Liu, Hongyi Tan, Chengxian Guo, Hao Zhang, Guoping Yang
Publikováno v:
Drug Design, Development and Therapy. 16:2261-2274
Chengxiao Fu,1,2,* Qi Pei,3,* Wu Liang,4 Bo Yang,2 Wei Li,5 Jun Liu,5 Hongyi Tan,1,4 Chengxian Guo,1,4 Hao Zhang,5 Guoping Yang1,4 1Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, Peopleâ
Autor:
Junlong, Ma, Wenjing, Chen, Zhanqing, Hu, Jie, Huang, Chengxian, Guo, Chan, Zou, Guoping, Yang
Publikováno v:
Investigational New Drugs. 40:861-867
Pertuzumab is a recombinant anti-HER2 humanized monoclonal antibody widely used for the adjuvant treatment of HER2-positive breast cancer. Its safety is well established with the most common adverse effects being diarrhea and rash. To our knowledge,