Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chengwu Chi"'
Autor:
Chengwu Chi, Xiaoqin Zou, Alyssa Moller, Jianmin Cui, Jingyi Shi, Chunguang Wang, Kelli McFarland, Longjin Yang, Xiao Yang, Min Li, Shan Chang
Publikováno v:
Journal of Biological Chemistry. 289:4735-4742
BK channel β subunits (β1-β4) modulate the function of channels formed by slo1 subunits to produce tissue-specific phenotypes. The molecular mechanism of how the homologous β subunits differentially alter BK channel functions and the role of diff
Autor:
Keith K. Khoo, Mingyu Ye, Matthew A. Perugini, Chengwu Chi, Xiao-Xia Shao, Mi Zhou, Charles A. Galea, Shaoqiong Xu, Raymond S. Norton, Chunguang Wang, Nonlawat Boonyalai
Publikováno v:
Journal of Biological Chemistry. 287:14973-14983
Cone snail venoms are a rich source of peptides, many of which are potent and selective modulators of ion channels and receptors. Here we report the isolation and characterization of two novel conotoxins from the venom of Conus imperialis. These two
Autor:
Mingyu Ye, Yanfang Wang, Xiao-Xia Shao, Edward Hawrot, Jing Liu, Chunguang Wang, Can Peng, Chengwu Chi, Duo-Duo Yuan
Publikováno v:
Peptides. 31:2009-2016
Two novel conotoxins from vermivorous cone snails Conus pulicarius and Conus tessulatus designated as Pu14 1 and ts14a were identified by cDNA cloning and peptide purification respectively The signal sequence of Pu14 1 is identical to that of alpha-c
Publikováno v:
Acta Biochimica et Biophysica Sinica. 42:502-505
Neuropeptide Y (NPY) is a ubiquitous endocrine neuropeptide found in vertebrate and invertebrate. In our present work, two NPY-like exocrine conopeptides (designated as cono-NPYs) were first identified in the venom of cone snails. Both cono-NPYs show
Publikováno v:
Peptides. 31:1001-1006
In our present work, seven conotoxins and conopeptides were cloned from four cone snail species based on the M-superfamily signal peptides. Among them, two conopeptides, Vt3.1 and Vt3.2, showed unusual sequence characteristics. Both of them contained
Autor:
ChengWu Chi
Publikováno v:
Chinese Science Bulletin. 54:2734-2745
Autor:
Shiva N. Kompella, Shaoqiong Xu, David J. Adams, Mengdi Yan, Aiping Lu, Tianlong Zhang, Chunguang Wang, Jianping Ding, Xiao-Xia Shao, Chengwu Chi, Yanfang Wang
Publikováno v:
Scientific Reports
Nicotinic acetylcholine receptors (nAChRs) play essential roles in transmitting acetylcholine-mediated neural signals across synapses and neuromuscular junctions and are also closely linked to various diseases and clinical conditions. Therefore, nove
Autor:
Chengwu Chi, Xiao-Xia Shao, Fred J. Sigworth, Donghai Lin, Lijun Huang, Youshan Yang, Chunguang Wang, Mingyu Ye, Mi Zhou, Jing Hong
A novel conotoxin, qc16a, was identified from the venom of vermivorous Conus quercinus. qc16a has only 11 amino acid residues, DCQPCGHNVCC, with a unique cysteine pattern. Its disulfide connectivity was determined to be I-IV, II-III. The NMR structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba398db49dcbf34472c8698ef3858d80
https://europepmc.org/articles/PMC3547678/
https://europepmc.org/articles/PMC3547678/
Autor:
Can, Peng, Weihua, Chen, Yuhong, Han, Tanya, Sanders, Geoffrey, Chew, Jing, Liu, Edward, Hawrot, Chengwu, Chi, Chunguang, Wang
Publikováno v:
Acta biochimica et biophysica Sinica. 41(10)
As part of continuing studies of the identification of gene organization and cloning of novel alpha-conotoxins, the first alpha4/4-conotoxin identified in a vermivorous Conus species, designated Qc1.2, was originally obtained by cDNA and genomic DNA
Publikováno v:
Acta biochimica et biophysica Sinica. 40(5)
Conotoxins are well known for their highly variable structures and functions. Here we report the identification of a novel conotoxin named mr1e from Conus marmoreus. mr1e is composed of 11 amino acid residues cross-linked by two disulfide bonds (CCHS