Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Chengsen, Xue"'
Autor:
Jeffrey E. Segall, John Condeelis, Erik Sahai, Zhong-Yin Zhang, Kun-Lin Tsai, Stefania Violini, Mazen Sidani, Fubo Liang, Jeffrey Wyckoff, Chengsen Xue
Supplementary Movie from Epidermal Growth Factor Receptor Overexpression Results in Increased Tumor Cell Motility In vivo Coordinately with Enhanced Intravasation and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbedf3e6c92a97c92f9e52bd0ee161c
https://doi.org/10.1158/0008-5472.22364660
https://doi.org/10.1158/0008-5472.22364660
Autor:
Jeffrey E. Segall, John Condeelis, Erik Sahai, Zhong-Yin Zhang, Kun-Lin Tsai, Stefania Violini, Mazen Sidani, Fubo Liang, Jeffrey Wyckoff, Chengsen Xue
Although overexpression of the epidermal growth factor receptor (EGFR; ErbB1) has been correlated with poor prognosis in breast and other cancers, clinical trials of ErbB1 inhibitors have shown limited efficacy in inhibiting tumor proliferation. To e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2797cb4b31020280f7853c53ee28f855
https://doi.org/10.1158/0008-5472.c.6494309.v1
https://doi.org/10.1158/0008-5472.c.6494309.v1
Autor:
Jeffrey E. Segall, Zhong-Yin Zhang, Joseph Locker, Mimi Kim, Kun-Lin Tsai, Hong Qian, Jeffrey Wyckoff, Magalis Vuolo, Radma Mahmood, Fubo Liang, Chengsen Xue
Supplementary Table 1 from ErbB3-Dependent Motility and Intravasation in Breast Cancer Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd9b0022bbb9a783434e64f9c0782f9
https://doi.org/10.1158/0008-5472.22366547.v1
https://doi.org/10.1158/0008-5472.22366547.v1
Autor:
Jeffrey E. Segall, Zhong-Yin Zhang, Joseph Locker, Mimi Kim, Kun-Lin Tsai, Hong Qian, Jeffrey Wyckoff, Magalis Vuolo, Radma Mahmood, Fubo Liang, Chengsen Xue
A better understanding of how epidermal growth factor receptor family members (ErbBs) contribute to metastasis is important for evaluating ErbB-directed therapies. Activation of ErbB3/ErbB2 heterodimers can affect both proliferation and motility. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c022e43da2970de51e849824703ae1
https://doi.org/10.1158/0008-5472.c.6495188
https://doi.org/10.1158/0008-5472.c.6495188
Autor:
Chengsen Xue, Timothy K. Amukele
Publikováno v:
Cancer Research. 82:1958-1958
Circulating Tumor Cells (CTC) are a prognostic biomarker for some types of malignant epithelial cancers and have been correlated with poor clinical outcomes. However, the routine measurement of CTC in clinical practice is still very uncommon and some
Autor:
Weiguo Zhong, Christina D. Swenson, Joanne Cuomo, Yeji Cho, Thomas W. Mc Closkey, Chengsen Xue
Publikováno v:
Cancer Research. 81:512-512
The success of inhibiting PD1 on T cells for cancer immunotherapy initiated strong interest in studying therapeutic antibodies to alter the adaptive immune system. As the knowledge of neoantigens, oncogenes, and autoantigens is rapidly accelerating,
Autor:
Joanne Cuomo, Chengsen Xue, Chrinstina D. Swenson, Kai Chen, Thomas W. Mc Closkey, Lucie-Emily Rows
Publikováno v:
Cancer Research. 80:5593-5593
Personalized immunotherapy for cancer has become an effective treatment choice in certain oncology indications. To successfully develop such therapeutic candidates requires a deep understanding of the biology including the interaction between a varie
Autor:
Kasia E. Cortes, Hong Ji, Anne Charlotte Hegelund, Carl-Magnus Högerkorp, Karen J. Quadrini, Chengsen Xue, Thomas W. Mc Closkey, Susan M. Kennelly
Publikováno v:
Cytometry Part B: Clinical Cytometry. 90:177-190
The C5a/C5a receptor (C5aR) pathway, a key component in the proinflammatory immune response, is an attractive therapeutic target since its dysregulation is implicated in a variety of autoimmune and inflammatory disorders. The objective of the present
Publikováno v:
Cancer Research. 78:5588-5588
Circulating tumor cell (CTC) detection and characterization have recently become an integral part of precision medicine. Several large, multicenter clinical studies confirmed that the prevalence of CTC is a useful predictor of treatment efficacy in m
Autor:
Maxime Melikian, Chengsen Xue, J.W. Chiao, Luxi Wang, Liying Han, Karim Solangi, Allen Tsao, John T. Fallon, Gildas Bertho, Long G. Wang, Simon Mencher
Publikováno v:
Biochemical pharmacology. 99
A small molecule, Natura-α, a clinical stage investigational new drug for certain inflammatory diseases, has been evaluated for drug interaction with STAT3 and inhibiting systemic lupus erythematosus (SLE). Studies have revealed that it selectively