Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chengqiong Mao"'
Autor:
Yong Lu, Ningbo Zheng, Ziyu Wang, Chengqiong Mao, Jing Fang, Xiaoyin Li, Guangxu Jin, Gang Xue, Xin Ming
Publikováno v:
Nature Biomedical Engineering. 5:1306-1319
Antigen release resulting from the death of tumour cells induced by chemotherapies and targeted therapies can augment the antitumour responses induced by immune checkpoint blockade (ICB). However, tumours responding to ICB therapies often become resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c697b6c708afca7f68cfb9fff746aef1
https://doi.org/10.1038/s41551-021-00799-6
https://doi.org/10.1038/s41551-021-00799-6
Autor:
Chengqiong Mao, Stacy Yeh, Juan Fu, Mercedes Porosnicu, Alexandra Thomas, Gregory L. Kucera, Konstantinos I. Votanopoulos, Shaomin Tian, Xin Ming
Publikováno v:
Sci Transl Med
Oncoimmunology
Oncoimmunology
Tumor evasion of immune destruction is associated with the production of immunosuppressive adenosine in the tumor microenvironment (TME). Anticancer therapies can trigger adenosine triphosphate (ATP) release from tumor cells, causing rapid formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ac2d5612c647ba9c156cf7550e985f
https://doi.org/10.1126/scitranslmed.abh1261
https://doi.org/10.1126/scitranslmed.abh1261
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 37(9)
Photoimmunotherapy (PIT) is an emerging tumor-targeted phototherapy that combines the tumor specificity of monoclonal antibodies with the phototoxicity of light absorbers to rapidly and selectively induce the immunogenic death of target tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::277b9d79f47d5fbfa079950f670573b0
https://pubmed.ncbi.nlm.nih.gov/34622619
https://pubmed.ncbi.nlm.nih.gov/34622619
Publikováno v:
Stimuli-Responsive Nanomedicine ISBN: 9780429295294
Stimuli-Responsive Nanomedicine
Stimuli-Responsive Nanomedicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::373be7e168ecab0eeffb1e20e677aa95
https://doi.org/10.1201/9780429295294-9
https://doi.org/10.1201/9780429295294-9
Publikováno v:
Journal of Controlled Release. 286:289-300
Drug resistance remains a formidable challenge to cancer therapy. P-glycoprotein (Pgp) contributes to multidrug resistance in numerous cancers by preventing accumulation of anticancer drugs in cancer cells. Strategies to overcome this resistance have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::968baba2b4819619257afa46ad2769de
https://doi.org/10.1016/j.jconrel.2018.08.005
https://doi.org/10.1016/j.jconrel.2018.08.005
Publikováno v:
Molecular Pharmaceutics. 15:2559-2569
Photodynamic therapy, a procedure that uses a photosensitizer to enable light therapy selectively at diseased sites, remains underutilized in oncological clinic. To further improve its cancer selectivity, we developed a polymeric nanosystem by conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12015d4d42cc4313926db0b76cca199
https://doi.org/10.1021/acs.molpharmaceut.8b00088
https://doi.org/10.1021/acs.molpharmaceut.8b00088
Autor:
Mark J. Suto, Xin Ming, Edward G Brown, Lindsey I. James, Rudolph L. Juliano, Chengqiong Mao, Ling Wang, Yamuna Ariyarathna, Francis X. Tavares
Publikováno v:
Nucleic Acids Research
The pharmacological effects of antisense and siRNA oligonucleotides are hindered by the tendency of these molecules to become entrapped in endomembrane compartments thus failing to reach their targets in the cytosol or nucleus. We have previously use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62aa5f7cdbef9838324655e4dcc387be
https://doi.org/10.1093/nar/gkx1320
https://doi.org/10.1093/nar/gkx1320
Publikováno v:
Theranostics
Cancer nanomedicines only modestly improve the overall survival of patients because their anticancer activity is limited by biological barriers posed by the tumor microenvironment. Currently, all the drugs in FDA-approved cancer nanomedicines are sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba6ccfeb8edd7c098788a25535abcbd9
https://doi.org/10.7150/thno.29580
https://doi.org/10.7150/thno.29580
Publikováno v:
International Journal of Pharmaceutics. 604:120760
Small cell lung cancer (SCLC), one of the most aggressive cancers, has a high mortality rate and poor prognosis, and the clinical therapeutic outcomes of multidrug resistant SCLC are even worse. Multidrug resistance protein 1 (MRP1), one of the ATP-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ec067a18cecba61bc9af0374a1a3a0
https://doi.org/10.1016/j.ijpharm.2021.120760
https://doi.org/10.1016/j.ijpharm.2021.120760
Publikováno v:
Molecular Pharmaceutics. 14:2793-2804
Advances in photodynamic therapy of cancer have been restrained by lack of cancer specificity and side effects to normal tissues. Molecularly targeted photodynamic therapy can achieve higher cancer specificity by combination of active cancer targetin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adb867991e546fdb9811317612285b9
https://doi.org/10.1021/acs.molpharmaceut.7b00321
https://doi.org/10.1021/acs.molpharmaceut.7b00321