Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Chengming Fei"'
Autor:
Youshan Zhao, Dong Wu, Chengming Fei, Juan Guo, Shuncheng Gu, Yang Zhu, Feng Xu, Zheng Zhang, Lingyun Wu, Xiao Li, Chunkang Chang
Publikováno v:
Haematologica, Vol 100, Iss 2 (2015)
Although it has been reported that mesenchymal stromal cells are unable to provide sufficient hematopoietic support in myelodysplastic syndrome, the underlying mechanisms remain elusive. In this study, we found that mesenchymal stromal cells from pat
Externí odkaz:
https://doaj.org/article/06ba9666697040d78e8084f13313c4b6
Publikováno v:
Aging (Albany NY)
Bone marrow stromal cells from patients with myelodysplastic syndrome (MDS) display a senescence phenotype, but the underlying mechanism has not been elucidated. Pro-inflammatory signaling within the malignant clone and the bone marrow microenvironme
Publikováno v:
International journal of oncology. 57(3)
Hepatocellular carcinoma (HCC) is the fourth most common cancer type worldwide, with a poor prognosis and high mortality rate. The aim of the present study was to investigate the mechanisms underlying HCC progression to potentially benefit the develo
Autor:
Sida Zhao, Juan Guo, Qingqing Zheng, Chao Xiao, Chengming Fei, Chunkang Chang, Lingyun Wu, Xiao Li, Youshan Zhao, Dong Wu
Publikováno v:
Cell Death and Disease, Vol 9, Iss 5, Pp 1-12 (2018)
Cell Death & Disease
Cell Death & Disease
Iron overload (IO) has been reported to contribute to mesenchymal stromal cell (MSC) damage, but the precise mechanism has yet to be clearly elucidated. In this study, we found that IO increased cell apoptosis and lowered cell viability in MSCs, acco
Autor:
Sida Zhao, Juan Guo, Lu-Xi Song, Youshan Zhao, Chunkang Chang, Zheng Zhang, Chengming Fei, Xiao Li, Qingqing Zheng
Publikováno v:
Leukemia Research. 58:55-62
Erythroid apoptosis increases significantly in myelodysplastic syndrome (MDS) patients with iron overload, but the underlying mechanism is not fully clear. In this study, we aim to explore the effect of HIF-1a/ROS on erythroid apoptosis in MDS patien
Autor:
Chengming Fei, Xiao Li, Chunkang Chang, Youshan Zhao, Qing-Qing Zhen, Sida Zhao, Juan Guo, Lei Shi
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Background Hyaluronan (HA), a major component of the extracellular matrix, has been proven to play a crucial role in tumor progression. However, it remains unknown whether HA exerts any effects in myelodysplastic syndromes (MDS). Methods A total of 8
Autor:
Chunkang Chang, Youshan Zhao, Qingqing Zheng, Sida Zhao, Jiying Su, Juan Guo, Chengming Fei, Xiao Li, Dong Wu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 5, Pp 1-15 (2018)
Cell Death and Disease, Vol 9, Iss 5, Pp 1-15 (2018)
Bone marrow mesenchymal stem cells (BMMSCs) facilitate the growth of multiple myeloma (MM) cells, but the underlying mechanisms remain unclear. This study demonstrates that the senescence of MM-MSCs significantly increased, as evidenced by a decrease
Autor:
Qingqing Zheng, Youshan Zhao, Sida Zhao, Jiying Su, Juan Guo, Chengming Fei, Xiao Li, Chunkang Chang, Dong Wu
Publikováno v:
Oncotarget
// Juan Guo 1 , Chengming Fei 1 , Youshan Zhao 1 , Sida Zhao 1 , Qingqing Zheng 1 , Jiying Su 1 , Dong Wu 1 , Xiao Li 1 and Chunkang Chang 1 1 Department of Hematology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 2002
Autor:
Shucheng Gu, Youshan Zhao, Chao Xiao, Chunkang Chang, Juan Guo, Feng Xv, Xiao Li, Chengming Fei, Yanjun Xv
Publikováno v:
Hematology (Amsterdam, Netherlands). 22(1)
In order to gain an insight into labile plasma iron (LPI) in iron metabolism microenvironment in MDS.We performed ELISA, quantitative real-time polymerase chain reaction, flow cytometry, MRI T2* assays to test LPI, iron biochemical parameters, and li
Autor:
Sida, Zhao, Juan, Guo, Youshan, Zhao, Chengming, Fei, Qingqing, Zheng, Xiao, Li, Chunkang, Chang
Publikováno v:
American journal of translational research. 8(7)
Many studies have indicated that histone deacetylase (HDAC) activity is always increased in a lot of human tumors, and inhibition of HDAC activity is a promising new strategy in the treatment of cancers. Chidamide, a novel HDAC inhibitor of the benza