Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Chengliang Lyu"'
Autor:
Chengliang Lyu, Zhanlong He, Xiaoming Hu, Shuang Wang, Meng Qin, Li Zhu, Yanyan Li, Fengmei Yang, Zhouguang Jiao, Xiao Zhang, Guihong Lu, Erqiang Wang, Yaling Hu, Yu Zhai, Youchun Wang, Weijin Huang, Dongshu Wang, Yimin Cui, Xiaocong Pang, Xiangzheng Liu, Hidehiro Kamiya, Guanghui Ma, Wei Wei
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The binding of viruses to host-entry factor receptors is an essential step for viral infection. Many studies have shown that macrophages can internalize viruses and degrade them in lysosomes for clearance in vivo. Inspired by these natural b
Externí odkaz:
https://doaj.org/article/2965242566f44633b42295bad8981c61
Autor:
Xiaoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang, Peidong Yang, Limin Wang, Guanghui Ma, Wei Wei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The spread of many infectious diseases relies on aerosol transmission to the respiratory tract. Here we design an intranasal mask comprising a positively-charged thermosensitive hydrogel and cell-derived micro-sized vesicles with a specific
Externí odkaz:
https://doaj.org/article/87dd44e7fb7645e0b5dd6630f80d46f6
Autor:
Guihong Lu, Xiaojun Wang, Feng Li, Shuang Wang, Jiawei Zhao, Jinyi Wang, Jing Liu, Chengliang Lyu, Peng Ye, Hui Tan, Weiping Li, Guanghui Ma, Wei Wei
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Targeting cancer-associated metabolism is evolving as a promising approach for cancer therapy. Here, the authors generate cancer cell-membrane encapsulated nanoparticles to induce cell cycle arrest and cytotoxicity in lactate-high cancer cells, reduc
Externí odkaz:
https://doaj.org/article/5266eb91342f4bb085f40bf369802534
Autor:
Pengcheng Luo, Dashuai Sun, Zeyu Lyu, Sida Shen, Zheng Lu, Zhijun Li, Zhihang Yue, Chengliang Lyu, Hongpeng You
Publikováno v:
Journal of Materials Chemistry C. 11:5515-5523
A novel Y2CaHfScAl3O12:Cr3+,Yb3+ NIR phosphor and application demonstration in the fields of information encryption and non-invasive detection.
Autor:
Yajie Liu, Xilin Bai, Chengliang Lyu, Jing Fang, Fan Zhang, Wen-Hao Wu, Wei Wei, Wen-Bin Zhang
Publikováno v:
Journal of the American Chemical Society. 144(40)
Bioconjugation is a powerful protein modification strategy to improve protein properties. Herein, we report mechano-bioconjugation as a novel approach to empower fusion protein therapeutics and demonstrate its utility by a protein heterocatenane (
Autor:
Jianghua Wang, Feng Li, Rongrong Jia, Guanghui Ma, Chengliang Lyu, Jun Ren, Di Yu, Wei Wei, Shuang Wang, Zhaowen Ding, Xiaoyong Gao, Shuang Qing, Tong Ye
Publikováno v:
Science translational medicine. 13(615)
Despite multiple immunotherapeutic technologies that achieve potent T cell activation, effector T cells still lack efficiency because of the highly immunosuppressive conditions in the tumor microenvironment. Inspired by recent advances in nano-sized
Autor:
Guanghui Ma, Shuang Qing, Shuang Wang, Chao Pan, Li Zhu, Chengliang Lyu, Wei Wei, Feng Li, Rongrong Jia, Jianghua Wang, Xiaoyong Gao, Hua Yue
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 32(47)
The highly immunosuppressive tumor microenvironment (TME) in solid tumors often dampens the efficacy of immunotherapy. In this study, bacterial outer membrane vesicles (OMVs) are demonstrated as powerful immunostimulants for TME reprogramming. To ove
Autor:
Feng Li, Guanghui Ma, Rongrong Jia, Li Zhu, Xiaoyong Gao, Wei Wei, Chao Pan, Shuang Wang, Chengliang Lyu, Hua Yue, Jianghua Wang, Shuang Qing
Publikováno v:
Advanced Materials. 32:2070350
Autor:
Weier Bao, Fan Zhang, Hidehiro Kamiya, Guihong Lu, Feng Li, Chengliang Lyu, Wei Wei, Guanghui Ma, Xiaoyong Gao, Shuang Wang
Publikováno v:
Chemical Engineering Journal. 398:125453
Hypoxia-inducible factor-1 (HIF-1) plays a critical role in tumor development and chemotherapy resistance, and suppression of HIF-1 has emerged as a captivating antitumor approach. To efficiently silence HIF-1 in deep hypoxic tumors, we herein develo
Autor:
Huiyu Liu, Yan Cui, Weiwei Wang, Bolong Xu, Hongyu Wang, Shuang Wang, Zhen Liu, Weier Bao, Chengliang Lyu, Wei Wei, Meng Qin, Shanshan Li
Publikováno v:
Advanced Materials. 32:2003563
Nanozyme-based tumor catalytic therapy has attracted widespread attention in recent years. However, its therapeutic outcomes are diminished by many factors in the tumor microenvironment (TME), such as insufficient endogenous hydrogen peroxide (H2 O2