Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Chenglai Xia"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-10 (2024)
Externí odkaz:
https://doaj.org/article/ceeb6a4e0db34bf58b74f64afd6cc301
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Dysregulation in histone acetylation, a significant epigenetic alteration closely associated with major pathologies including cancer, promotes tumorigenesis, inactivating tumor-suppressor genes and activating oncogenic pathways. A
Externí odkaz:
https://doaj.org/article/9ad56304106049e5925bc82ddd268493
Autor:
Fang Wang, Kai Fu, Yujue Wang, Can Pan, Xueping Wang, Zeyu Liu, Chuan Yang, Ying Zheng, Xiaopeng Li, Yu Lu, Kenneth Kin Wah To, Chenglai Xia, Jianye Zhang, Zhi Shi, Zeping Hu, Min Huang, Liwu Fu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 905-952 (2024)
Cancer immunotherapy, exemplified by the remarkable clinical benefits of the immune checkpoint blockade and chimeric antigen receptor T-cell therapy, is revolutionizing cancer therapy. They induce long-term tumor regression and overall survival benef
Externí odkaz:
https://doaj.org/article/06e7be5579fb4a6c9c58d69cff3d3f9c
Autor:
Dahai Liu, Qiang Fu, Leyna G. Liu, Wenwen Li, Fei Qi, Justin Liu, Lifeng Shang, Xiu Wang, Fang Yang, Jie Li, Daoqiang Lu, Huiying Feng, Ziwen Zhang, Yiqing Chen, Junru Liang, Jiayi Yao, Hua Lv, Riwang Li, Jun Wang, Di Wu, Yuxi Liu, Chenglai Xia, Wenxing Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Background: The Juan-Bi decoction (JBD) is a classic traditional Chinese medicines (TCMs) prescription for the treatment of rheumatoid arthritis (RA). However, the active compounds of the JBD in RA treatment remain unclear.Aim: The aim of this study
Externí odkaz:
https://doaj.org/article/34096517501747a2bb5531174933600c
Autor:
Yinyan Li, Huiting Sang, Qinxian Mo, Linrui Jiang, Zhixuan Chen, Jinlong Liang, Chunyu Zhang, Zhengyin Zhang, Chenglai Xia, Jie Yang
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 2, Pp 100553- (2024)
Background: Cepharanthine (CEP), a natural bis-benzylisoquinoline alkaloid extracted from the plant Stephania cephalantha Hayata, has been widely used to treat several acute and chronic diseases. However, its antiviral potential against influenza A v
Externí odkaz:
https://doaj.org/article/5719648cd945472fb614543f98db7e27
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-24 (2023)
Abstract Cancer stem-like cells (CSCs), a subpopulation of cancer cells, possess remarkable capability in proliferation, self-renewal, and differentiation. Their presence is recognized as a crucial factor contributing to tumor progression and metasta
Externí odkaz:
https://doaj.org/article/5968dcbdead9443680939e17dee47831
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115853- (2023)
Exosomes are nano-scale extracellular vesicles that are found widely in various biological fluids. As messengers, exosomes deliver characteristic biological information from donor cells, facilitating their accumulation and subsequent transfer of info
Externí odkaz:
https://doaj.org/article/b734d61dc327496586c2241772a82e21
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Cancer development is closely associated with immunosuppressive tumor microenvironment (TME) that attenuates antitumor immune responses and promotes tumor cell immunologic escape. The sequential conversion of extracellular ATP into adenosine
Externí odkaz:
https://doaj.org/article/6d26402fc76e4c14b1abd991152338c3
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115021- (2023)
The neuroprotective effects of Er-Zhi-Wan (EZW), a well-known traditional Chinese formulation, in MPTP-induced Parkinson’s disease (PD) models are poorly understood and require evaluation. A model of PD induced by MPTP was used to evaluate the neur
Externí odkaz:
https://doaj.org/article/8270b4db799c4e5e9c55f0aeb27fb1ea
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The human gut microbiota is a complex ecosystem regulating the host’s environmental interaction. The same functional food or drug may have varying bioavailability and distinct effects on different individuals. Drugs such as antibiotics can alter th
Externí odkaz:
https://doaj.org/article/7cee0a987758450db0d61f1bafd9e9f9