Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Chengji J. Zhou"'
Autor:
Chao Li, Yuming Feng, Zhenxin Fu, Junjie Deng, Yue Gu, Hanben Wang, Xin Wu, Zhengyun Huang, Yichen Zhu, Zhiwei Liu, Moli Huang, Tao Wang, Shijun Hu, Bing Yao, Yizhun Zeng, Chengji J. Zhou, Steve D. M. Brown, Yi Liu, Antonio Vidal-Puig, Yingying Dong, Ying Xu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Exploring the functions of human-specific genes (HSGs) is challenging due to the lack of a tractable genetic model system. Testosterone is essential for maintaining human spermatogenesis and fertility, but the underlying mechanism is unclear
Externí odkaz:
https://doaj.org/article/36ba28c778ba4b7e885435790986db95
Autor:
Ghazi-Abdullah Saroya, Erica Siismets, Max Hu, Christopher Panaretos, Adam Rice, Kurt Reynolds, Chengji J. Zhou, Vesa Kaartinen
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
The secondary palate forms from two lateral primordia called the palatal shelves which form a contact in the midline, become adherent at the fusing interface (medial edge epithelia, MEE) and subsequently fuse. The gene encoding transforming growth fa
Externí odkaz:
https://doaj.org/article/4de32e911a1b49d8aecd54bf2ded99ff
Autor:
Tianyu Zhao, Moira McMahon, Kurt Reynolds, Subbroto Kumar Saha, Arjun Stokes, Chengji J. Zhou
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
Neural tube defects (NTDs) are among the common and severe birth defects with poorly understood etiology. Mutations in the Wnt co-receptor LRP6 are associated with NTDs in humans. Either gain-of-function (GOF) or loss-of-function (LOF) mutations of L
Externí odkaz:
https://doaj.org/article/05a0b7f1b2b342fba5f8191074b192bc
Autor:
Tao Zhang, Xiaojiao Du, Yue Gu, Yingying Dong, Wei Zhang, Zhirong Yuan, Xingmei Huang, Cao Zou, Yafeng Zhou, Zhiwei Liu, Hui Tao, Ling Yang, Gang Wu, John B. Hogenesch, Chengji J. Zhou, Fei Zhou, Ying Xu
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Circadian factors likely influence the occurrence, development, therapy, and prognosis of cardiovascular diseases (CVDs). To determine the association between the heart rate (HR) diurnal parameters and CVD risks, we designed an analytical strategy to
Externí odkaz:
https://doaj.org/article/51359edb749e4ce686d8c7b91a119804
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 11, Iss 1, Pp 1-14 (2019)
Abstract Background The development of an autistic brain is a highly complex process as evident from the involvement of various genetic and non-genetic factors in the etiology of the autism spectrum disorder (ASD). Despite being a multifactorial neur
Externí odkaz:
https://doaj.org/article/d969a42798614336a0c285da7eef1c3e
Autor:
René St-Arnaud, Martin Pellicelli, Mahmoud Ismail, Alice Arabian, Toghrul Jafarov, Chengji J. Zhou
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 940 (2022)
PTH induces phosphorylation of the transcriptional coregulator NACA on serine 99 through Gαs and PKA. This leads to nuclear translocation of NACA and expression of the target gene Lrp6, encoding a coreceptor of the PTH receptor (PTH1R) necessary for
Externí odkaz:
https://doaj.org/article/cfb112648d7f47778057fe62e424913a
Autor:
Kurt Reynolds, Priyanka Kumari, Lessly Sepulveda Rincon, Ran Gu, Yu Ji, Santosh Kumar, Chengji J. Zhou
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 2 (2019)
Diverse signaling cues and attendant proteins work together during organogenesis, including craniofacial development. Lip and palate formation starts as early as the fourth week of gestation in humans or embryonic day 9.5 in mice. Disruptions in thes
Externí odkaz:
https://doaj.org/article/bbcd765e2ecc455eb6f2a3851532a560
Publikováno v:
Cells, Vol 8, Iss 10, p 1173 (2019)
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic de
Externí odkaz:
https://doaj.org/article/7649eb743eef4415b785b4eae76c8b1c
Publikováno v:
Birth Defects Res
Orofacial clefts (OFCs) are among the most common birth defects and impart a significant burden on afflicted individuals and their families. It is increasingly understood that many nonsyndromic OFCs are a consequence of extrinsic factors, genetic sus
Publikováno v:
Birth Defects Res
Craniofacial development involves several complex tissue movements including several fusion processes to form the frontonasal and maxillary structures, including the upper lip and palate. Each of these movements are controlled by many different facto