Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chengji, Piao"'
Publikováno v:
PLoS Biology, Vol 20, Iss 12, p e3001730 (2022)
The brain as a central regulator of stress integration determines what is threatening, stores memories, and regulates physiological adaptations across the aging trajectory. While sleep homeostasis seems to be linked to brain resilience, how age-assoc
Externí odkaz:
https://doaj.org/article/2147b99477634435a4e7186b7ea6ca41
Autor:
Chengji Piao, Stephan J. Sigrist
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2022)
The so-called active zones at pre-synaptic terminals are the ultimate filtering devices, which couple between action potential frequency and shape, and the information transferred to the post-synaptic neurons, finally tuning behaviors. Within active
Externí odkaz:
https://doaj.org/article/b4af6fe7df4b43db80f42ad0bdddb2e5
Autor:
YongTian Liang, Chengji Piao, Christine B. Beuschel, David Toppe, Laxmikanth Kollipara, Boris Bogdanow, Marta Maglione, Janine Lützkendorf, Jason Chun Kit See, Sheng Huang, Tim O.F. Conrad, Ulrich Kintscher, Frank Madeo, Fan Liu, Albert Sickmann, Stephan J. Sigrist
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108941- (2021)
Summary: Mitochondrial function declines during brain aging and is suspected to play a key role in age-induced cognitive decline and neurodegeneration. Supplementing levels of spermidine, a body-endogenous metabolite, has been shown to promote mitoch
Externí odkaz:
https://doaj.org/article/973855efe1694596aa789d1da04bdb4d
Autor:
Chengji, Piao, Stephan J, Sigrist
Publikováno v:
Frontiers in Synaptic Neuroscience
The so-called active zones at pre-synaptic terminals are the ultimate filtering devices, which couple between action potential frequency and shape, and the information transferred to the post-synaptic neurons, finally tuning behaviors. Within active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50c40c1f6b6ef7cf99961c6f3053d582
https://pubmed.ncbi.nlm.nih.gov/35046788
https://pubmed.ncbi.nlm.nih.gov/35046788
Autor:
Xingyue Wang, Xing Chen, Nan Sui, Lian Ma, Xuekun Ding, Chengji Piao, Tiane Liu, Ying Duan, Jing Liang
Publikováno v:
Psychopharmacology. 234:2941-2953
The inability to stop a repetitive maladaptive behavior is a main problem in addictive disorders. Neuroadaptations that are associated with behavioral inflexibility may be involved in compulsive drug use. The aim of the present study was to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae9bc6d389710cc1a44b4a4d360dbf7
https://doi.org/10.1007/s00213-017-4689-3
https://doi.org/10.1007/s00213-017-4689-3
Publikováno v:
Behavioural Brain Research. 317:16-26
The medial prefrontal cortex (mPFC) and its output area, the nucleus accumbens (NAc), are implicated in mediating attentional set-shifting. Patients with posttraumatic stress disorder (PTSD) exhibit difficulties in the disengagement of attention from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea594cca20cdbfed8301a3bf61234f1
https://doi.org/10.1016/j.bbr.2016.09.017
https://doi.org/10.1016/j.bbr.2016.09.017
Autor:
Christine B. Beuschel, Fan Liu, Boris Bogdanow, Tim Conrad, Frank Madeo, Ulrich Kintscher, Stephan J. Sigrist, YongTian Liang, Marta Maglione, Janine Lützkendorf, Jason Chun Kit See, David Toppe, Sheng Huang, Albert Sickmann, Laxmikanth Kollipara, Chengji Piao
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108941-(2021)
Summary: Mitochondrial function declines during brain aging and is suspected to play a key role in age-induced cognitive decline and neurodegeneration. Supplementing levels of spermidine, a body-endogenous metabolite, has been shown to promote mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b89487961d5270ec964f941472ab78e
https://pubmed.ncbi.nlm.nih.gov/33852845
https://pubmed.ncbi.nlm.nih.gov/33852845
Phosphorylation of the Bruchpilot N-terminus unlocks axonal transport of active zone building blocks
Autor:
Ulrich Stelzl, Benno Kuropka, Martin Lehmann, Jan H. Driller, Albert Sickmann, Markus C. Wahl, Christoph Weise, Christian Freund, Janine Lützkendorf, René P. Zahedi, Astrid G. Petzoldt, Stephan J. Sigrist, Matthias Siebert, Chengji Piao, Harald Depner
Publikováno v:
Journal of Cell Science.
Protein scaffolds at presynaptic active zone membranes control information transfer at synapses. For scaffold biogenesis and maintenance, scaffold components must be safely transported along axons. A spectrum of kinases was suggested to control trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce71bd375c56a570b5e46560071b23de
https://doi.org/10.1242/jcs.225151
https://doi.org/10.1242/jcs.225151
Publikováno v:
Neurobiology of Learning and Memory. 128:80-91
The return of learned fear is an important issue in anxiety disorder research since an analogous process may contribute to long-term fear maintenance or clinical relapse. A number of studies demonstrate that mPFC and hippocampus are important in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e608218359123db7498ff5fa52c86e
https://doi.org/10.1016/j.nlm.2015.12.006
https://doi.org/10.1016/j.nlm.2015.12.006
Publikováno v:
Current Biology. 30:1077-1091.e5
Sleep is universal across species and essential for quality of life and health, as evidenced by the consequences of sleep loss. Sleep might homeostatically normalize synaptic gains made over wake states in order to reset information processing and st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d6484ce256629c0d2bb89bfb4bcec6
https://doi.org/10.1016/j.cub.2020.01.019
https://doi.org/10.1016/j.cub.2020.01.019