Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chenghuan Song"'
Autor:
Chenghuan Song, Wanying Huang, Pingao Zhang, Jiyun Shi, Ting Yu, Jing Wang, Yongbo Hu, Lanxue Zhao, Rui Zhang, Gang Wang, Yongfang Zhang, Hongzhuan Chen, Hao Wang
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-22 (2024)
Abstract Background Lysosomal homeostasis and functions are essential for the survival of neural cells. Impaired lysosomal biogenesis and acidification in Alzheimer’s disease (AD) pathogenesis leads to proteolytic dysfunction and neurodegeneration.
Externí odkaz:
https://doaj.org/article/3ea5a9c842a046a092488d50aaae8355
Autor:
Chenghuan Song, Jiyun Shi, Pingao Zhang, Yongfang Zhang, Jianrong Xu, Lanxue Zhao, Rui Zhang, Hao Wang, Hongzhuan Chen
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-17 (2022)
Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disease in the elderly worldwide. However, the complexity of AD pathogenesis leads to discrepancies in the understanding of this disease, and may be the main reason for the fail
Externí odkaz:
https://doaj.org/article/8b2790d9188a4fe194f73addf8d4c61c
Autor:
Tao Wang, Wanying Huang, Minjie Jiang, Chenghuan Song, Yu Qiu, Qiang Huang, Hongzhuan Chen, Yongfang Zhang, Jiyun Shi, Hao Wang
Publikováno v:
Cell Death Differ
Circular RNAs (circRNAs) have gained growing attention in participating in various biological processes and referring to multiply kinds of diseases. Although differentially expressed circRNA profiling in Alzheimer's disease (AD) has been established,
Autor:
Chenghuan Song, Jiyun Shi, Pingao Zhang, Yongfang Zhang, Jianrong Xu, Lanxue Zhao, Rui Zhang, Hao Wang, Hongzhuan Chen
Publikováno v:
Translational neurodegeneration. 11(1)
Alzheimer’s disease (AD) is the most common neurodegenerative disease in the elderly worldwide. However, the complexity of AD pathogenesis leads to discrepancies in the understanding of this disease, and may be the main reason for the failure of AD
Autor:
Rui Zhang, Yu Qiu, Wanying Huang, Chenghuan Song, Lan-Xue Zhao, Hongzhuan Chen, Yongfang Zhang, Jianrong Xu, Jiyun Shi, Hao Wang
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(6)
Alzheimer's disease (AD) is a complicated neurodegenerative disease and therefore addressing multiple targets simultaneously has been believed as a promising therapeutic strategy against AD. α7 nicotinic acetylcholine receptor (nAChR), which plays a
Autor:
Miaomiao Chen, Nanshan Song, Xi-Yang Sun, Qingling Jiang, Chenghuan Song, Jian-Hua Ding, Yinquan Fang, Gang Hu, Ming Lu
Publikováno v:
Biochemical Pharmacology. 150:245-255
β2-Aderenergic receptor (β2AR) agonist, Salmeterol exhibits anti-inflammatory activities. However, the inhibitory effects of Salmeterol on inflammasome activation are elusive and the underlying mechanisms need to be explored. In this study, we esta
Autor:
Chenghuan Song, Jiyun Shi, Jianrong Xu, Lanxue Zhao, Yongfang Zhang, Wanying Huang, Yu Qiu, Rui Zhang, Hongzhuan Chen, Hao Wang
Publikováno v:
FASEB Journal; Jun2021, Vol. 35 Issue 6, p1-17, 17p, 7 Graphs
Publikováno v:
Molecular neurobiology. 55(11)
The loss of dopaminergic (DA) neurons in the substantia nigra (SN) is a major feature in the pathology of Parkinson’s disease (PD). Using neural stem or progenitor cells (NSC/NPCs), the prospect of replacing the missing or damaged DA neurons is ver