Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Chenghao Xuan"'
Autor:
Ran Zhao, Yanxuan Guo, Linlin Zhang, Zhiyong Huang, Xuanyuan Li, Bei Lan, Diansheng Zhong, Hao Chen, Chenghao Xuan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality worldwide. Understanding the dysregulated epigenetics governing LUAD progression is pivotal for identifying therapeutic targets. CBX4, a chromobox protein, is rep
Externí odkaz:
https://doaj.org/article/ac3c2249a76f4de4bb48019747c6c6f7
Autor:
Xiaochuan Liu, Hao Chen, Zekun Li, Xiaoxiao Yang, Wen Jin, Yuting Wang, Jian Zheng, Long Li, Chenghao Xuan, Jiapei Yuan, Yang Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Alternative polyadenylation can occur in introns, termed intronic polyadenylation (IPA), has been implicated in diverse biological processes and diseases, as it can produce noncoding transcripts or transcripts with truncated coding regions.
Externí odkaz:
https://doaj.org/article/c91a13615d854daf82986671bf5900e0
Autor:
Fei-Fei Hu, Hao Chen, Yang Duan, Bei Lan, Chun-Jie Liu, Hui Hu, Xu Dong, Qiong Zhang, Yi-Ming Cheng, Min Liu, An-Yuan Guo, Chenghao Xuan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 670-684 (2022)
The disruption of epigenetic regulation is common in tumors; the abnormal expression of epigenetic factors leads to cancer occurrence and development. In this study, to investigate the potential function of histone methylation regulators in lung aden
Externí odkaz:
https://doaj.org/article/90c6575aeb244a54bd5fd9df7303694b
Autor:
Xingyan Zhang, Yaoyao Zhou, Zhenyu Shi, Zhenfeng Liu, Hao Chen, Xiaochen Wang, Yiming Cheng, Lishan Xi, Xuanyuan Li, Chunze Zhang, Li Bao, Chenghao Xuan
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Background Genes participating in chromatin organization and regulation are frequently mutated or dysregulated in cancers. ATP‐dependent chromatin remodelers (ATPCRs) play a key role in organizing genomic DNA within chromatin, therefore re
Externí odkaz:
https://doaj.org/article/ffe7d63cc69241f2b8aafe9ddb229185
Autor:
Yang Duan, Dawei Huo, Jie Gao, Heng Wu, Zheng Ye, Zhe Liu, Kai Zhang, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Xiang Ding, Lei Shi, Yan Wang, Yongfeng Shang, Chenghao Xuan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Eg5 has a role in spindle assembly and has been associated with tumorigenesis but it is not clear how its activity is regulated. Here, the authors show that the E3 ligase RNF20/40 regulates mitotic spindle assembly by regulating the stability of Eg5
Externí odkaz:
https://doaj.org/article/6442b2c4a6ff46e485d617184856d10d
Autor:
Yang Duan, Dawei Huo, Jie Gao, Heng Wu, Zheng Ye, Zhe Liu, Kai Zhang, Lin Shan, Xing Zhou, Yue Wang, Dongxue Su, Xiang Ding, Lei Shi, Yan Wang, Yongfeng Shang, Chenghao Xuan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-2 (2016)
Nature Communications 7: Article number: 12648 (2014); Published: 25 August 2016; Updated: 4 November 2016 In Fig. 1a of this Article, the locations of labels for TPM3 and RPS3 protein bands are incorrect. The correct version of Fig. 1 appears below.
Externí odkaz:
https://doaj.org/article/cb01b46153dd4be9af20ba0c70fee812
Autor:
Chenghao Xuan, Fengxia Xue, Yingmei Wang, Lishan Xi, Yiming Cheng, Zhenfeng Liu, Shengyun Feng, Hao Chen, Xiaochen Wang, Xingyan Zhang, Bei Lan, Ran Zhao, Xuanyuan Li, Yang Duan, Yanjie Wu
Supplementary Data from CBX8 Together with SET Facilitates Ovarian Carcinoma Growth and Metastasis by Suppressing the Transcription of SUSD2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897aa15ae00844aeede6edd60387d4b3
https://doi.org/10.1158/1541-7786.22527960
https://doi.org/10.1158/1541-7786.22527960
Autor:
Fei-Fei Hu, Hao Chen, Yang Duan, Bei Lan, Chun-Jie Liu, Hui Hu, Xu Dong, Qiong Zhang, Yi-Ming Cheng, Min Liu, An-Yuan Guo, Chenghao Xuan
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 670-684 (2022)
Molecular Therapy: Nucleic Acids, Vol 27, Iss, Pp 670-684 (2022)
The disruption of epigenetic regulation is common in tumors; the abnormal expression of epigenetic factors leads to cancer occurrence and development. In this study, to investigate the potential function of histone methylation regulators in lung aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82f93b2bf07b59de976842fb877d167
http://europepmc.org/articles/PMC8760531
http://europepmc.org/articles/PMC8760531
Autor:
Xiao Liang, Jun Xiao, Xuzichao Li, Yujie Liu, Yao Lu, Yanan Wen, Zexing Li, Xing Che, Yongjian Ma, Xingyan Zhang, Yi Zhang, Deng Jian, Peihui Wang, Chenghao Xuan, Guimei Yu, Long Li, Heng Zhang
Publikováno v:
Nature chemical biology. 18(11)
The E3 ligase TRIM7 has emerged as a critical player in viral infection and pathogenesis. However, the mechanism governing the TRIM7-substrate association remains to be defined. Here we report the crystal structures of TRIM7 in complex with 2C peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342cecadfd81abbeb628e04c659a85c3
https://pubmed.ncbi.nlm.nih.gov/36266348
https://pubmed.ncbi.nlm.nih.gov/36266348
Publikováno v:
Cell Death and Differentiation
The initiation and transduction of DNA damage response (DDR) occur in the context of chromatin, and modifications as well as the structure of chromatin are crucial for DDR signaling. How the profound chromatin alterations are confined to DNA lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd72d83417875e9c9713ae8a940479b4
http://europepmc.org/articles/PMC7206091
http://europepmc.org/articles/PMC7206091