Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Chenggui Miao"'
Autor:
Xiaomei Wang, Qiuyun Xue, Qiangjun Duan, Ziyi Sun, Yajie Wu, Shuo Yang, Pengfei Xu, Huibo Cao, Faxue Liao, Xiao Wang, Chenggui Miao
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
AbstractOur previous study found that Cullin 4B (CUL4B) inhibited rheumatoid arthritis (RA) pathology through glycogen synthase kinase-3beta (GSK3β)/canonical Wnt signalling pathway. In this work, pre-experiment and bioinformatics analysis suggested
Externí odkaz:
https://doaj.org/article/453ce0553a0e4b7f9db7433bc06b9f45
Autor:
Yanhui Peng, Yurong Huang, Hui Li, Chen Li, Yajie Wu, Zhe-Sheng Chen, Xiao Wang, Faxue Liao, Chenggui Miao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundChanges in intestinal flora and intestinal barrier in patients with preclinical and diagnosed rheumatoid arthritis (RA) suggest that intestinal flora and intestinal barrier play an important role in the induction and persistence of RA. Huan
Externí odkaz:
https://doaj.org/article/625200ef8bed44cfb5de4a7cb3dbba62
Wilforine inhibits rheumatoid arthritis pathology through the Wnt11/β-catenin signaling pathway axis
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Wilforine (WFR) is a monomeric compound of the anti-RA plant Tripterygium wilfordii Hook. f. (TwHF). Whether WFR has anti-RA effect, its molecular mechanism has not been elucidated. Aim of the study Our study aims to clarify how W
Externí odkaz:
https://doaj.org/article/68c39bf31e77480ea3c49e4904ffdc2e
Autor:
Yurong Huang, Qiuyun Xue, Jun Chang, Yuting Wang, Chenglong Cheng, Suowen Xu, Xiao Wang, Chenggui Miao
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background N6-methyladenosine (m6A) methylation modification is involved in the regulation of various biological processes, including inflammation, antitumor, and antiviral immunity. However, the role of m6A modification in the pathogenesis
Externí odkaz:
https://doaj.org/article/f44ad434ad6d48e0b3c01456a0eae403
Autor:
Chenglong Cheng, Yajie Wu, Xin Wang, Qiuyun Xue, Yurong Huang, Faxue Liao, Xiao Wang, Qiangjun Duan, Chenggui Miao
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Hepatic fibrosis (HF) is a pathological process caused by excessive accumulation of extracellular matrix caused by a series of causes, leading to the formation of fiber scar. RNA methylation is a newly discovered epigenetic modifi
Externí odkaz:
https://doaj.org/article/b5d2f69209b344ffbb7b29cdd82d9cfb
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the world. Despite considerable progress in the diagnosis, treatment and prognosis of CVDs, new diagnostic biomarkers and new therapeutic measures are urgently needed
Externí odkaz:
https://doaj.org/article/a5846821306f46a7924ca54169ce249f
Autor:
Xiao Wang, Jun Chang, Guoliang Zhou, Chenglong Cheng, Youyi Xiong, Jinfeng Dou, Gen Cheng, Chenggui Miao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The pathogenesis of rheumatoid arthritis (RA) is still not fully clarified, and the development of therapeutic drugs for RA is particularly urgent. Our group studies a possibility that circ_ 0015756/miR-942-5p may participate in the pathogenesis of R
Externí odkaz:
https://doaj.org/article/c585c4c9000a4c3fb59649b438c50a5b
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 3, Pp 201-208 (2019)
Objectives: The therapeutic potentiality of Bazhengsan on the chronic nonbacterial prostatitis was investigated. Methods: Prostatitis was induced by subcutaneous injection of the 17-beta-estradiol (E2) and dihydrotestosterone in male rat, and treated
Externí odkaz:
https://doaj.org/article/ef428a98c38e43c2af08bbbdfa158d88
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Osteoarthritis (OA) is a kind of degenerative disease, which is caused by many factors such as aging, obesity, strain, trauma, congenital joint abnormalities, joint deformities. Exosomes are mainly derived from the invagination of intracellular lysos
Externí odkaz:
https://doaj.org/article/0aef408213484f20acb0f1c05a7096d7
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs), inflammation, synovial hyperplasia and cartilage erosion, accompanied by joi
Externí odkaz:
https://doaj.org/article/ad6792d05687484d89d1c22b2bf26faa