Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chenggong Zong"'
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103178- (2024)
To this date, COVID-19 remains an unresolved pandemic, and the impairment of redox homeostasis dictates the severity of clinical outcomes. Here we examined initial UCLA cohort of 440 COVID-19 patients hospitalized between March 1st and April 1st, 202
Externí odkaz:
https://doaj.org/article/2d9ffc5d91d44e36a4ab30d6a8d1cc53
Autor:
Matthew A. Fischer, Kimberly Howard-Quijano, Nobel Chenggong Zong, Ji Youn Youn, Norika Mengchia Liu, Jennifer Scovotti, Tristan Grogan, Aman Mahajan, Hua Cai
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 971 (2024)
Background: Postoperative atrial fibrillation (POAF) and acute kidney injury (AKI) are common yet significant complications after cardiac surgery, with incidences of up to 40% for each. Here, we assessed plasma nitrite and serum interleukin-6 (IL-6)
Externí odkaz:
https://doaj.org/article/b2a76435a2724a64a261e46a123467d3
Reversal of Pulmonary Hypertension in a Human-Like Model: Therapeutic Targeting of Endothelial DHFR.
Autor:
Murugesan, Priya, Zhang, Yixuan, Huang, Yuanli, Chenggong Zong, Nobel, Youn, Ji Youn, Chen, Wenhui, Wang, Chen, Loscalzo, Joseph, Cai, Hua
Publikováno v:
Circulation Research; 2/16/2024, Vol. 134 Issue 4, p351-370, 20p
Autor:
Edward Lau, Ding Wang, Maggie P.Y. Lam, Kym F. Faull, Peipei Ping, Tae-Young Kim, Chenggong Zong, Sarah B. Scruggs, Christopher M. Ryan
Publikováno v:
Journal of Proteomics. 75:4602-4609
The regulation of mitochondrial function is essential for cardiomyocyte adaptation to cellular stress. While it has long been understood that phosphorylation regulates flux through metabolic pathways, novel phosphorylation sites are continually being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15844d6753cf466e38c994d669fc9450
https://doi.org/10.1016/j.jprot.2012.02.014
https://doi.org/10.1016/j.jprot.2012.02.014
Autor:
James N. Weiss, Paavo Korge, Peipei Ping, Wenhai Wang, Yibin Wang, Huilong Duan, Christopher Lotz, Yueju Wang, Rolf Apweiler, Glen Young, Pengyuan Yang, Haojie Lu, Jun Zhang, David A. Liem, Ning Deng, Philip Doran, Chenggong Zong
Publikováno v:
Molecular & Cellular Proteomics. 10:S1-S14
Mitochondrial functions are dynamically regulated in the heart. In particular, protein phosphorylation has been shown to be a key mechanism modulating mitochondrial function in diverse cardiovascular phenotypes. However, site-specific phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b774f4a8c0d780d575374c7705fe227
https://doi.org/10.1074/mcp.m110.000117
https://doi.org/10.1074/mcp.m110.000117
Autor:
Mansoureh Eghbali, Aldrin V. Gomes, Yueju Wang, Peipei Ping, Chenggong Zong, Enrico Stefani, Oliver Drews, Glen Young, Haojie Lu
Publikováno v:
Molecular & Cellular Proteomics. 8:302-315
The 20 S proteasome complexes are major contributors to the intracellular protein degradation machinery in mammalian cells. Systematic administration of proteasome inhibitors to combat disease (e.g. cancer) has resulted in positive outcomes as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbb9d4ec2f6a81ea92d90748c49cdff
https://doi.org/10.1074/mcp.m800058-mcp200
https://doi.org/10.1074/mcp.m800058-mcp200
Publikováno v:
PROTEOMICS. 8:5025-5037
Post-translational modifications (PTMs) serve as key regulatory mechanisms for 20S proteasome functions. Alterations in 20S PTMs have been previously observed with changes in modified protein degradation patterns and altered cellular phenotypes. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84181cc33ad80d59f74aff83027ce9bb
https://doi.org/10.1002/pmic.200800387
https://doi.org/10.1002/pmic.200800387
Autor:
Peipei Ping, Julian P. Whitelegge, Glen Young, Haojie Lu, Ning Deng, Chenggong Zong, Pete Souda, Xiaohai Li, Yueju Wang, Oliver Drews, Pengyuan Yang
Publikováno v:
Molecular & Cellular Proteomics. 7:2073-2089
The 20 S proteasomes play a critical role in intracellular homeostasis and stress response. Their function is tuned by covalent modifications, such as phosphorylation. In this study, we performed a comprehensive characterization of the phosphoproteom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37eb0a25b213cc652e248d6d19ec8baf
https://doi.org/10.1074/mcp.m800064-mcp200
https://doi.org/10.1074/mcp.m800064-mcp200
Autor:
Thomas M. Vondriska, Peipei Ping, Chenggong Zong, James N. Weiss, Yueju Wang, Jeong In Yang, Michael Mueller, Paavo Korge, Rolf Apweiler, Ning Deng, David A. Liem, Xiaohai Li, Henry M. Honda, Jun Zhang
Publikováno v:
PROTEOMICS. 8:1564-1575
Mitochondria play essential roles in cardiac pathophysiology and the murine model has been extensively used to investigate cardiovascular diseases. In the present study, we characterized murine cardiac mitochondria using an LC/MS/MS approach. We extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d91c35d373f0ac3207f10c3ff20b00a
https://doi.org/10.1002/pmic.200700851
https://doi.org/10.1002/pmic.200700851
Autor:
Chenggong Zong, Aldrin V. Gomes, Ute Sukop, Peipei Ping, Robert Wildgruber, Gerhard Weber, Mikkel Nissum, Oliver Drews
Publikováno v:
Molecular & Cellular Proteomics. 6:2021-2031
The proteasome-dependent protein degradation participates in multiple essential cellular processes. Modulation of proteasomal activities may alter cardiac function and disease phenotypes. However, cardiovascular studies reported thus far have yielded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8c12c663fe5c8bd528fb885d11e99f
https://doi.org/10.1074/mcp.m700187-mcp200
https://doi.org/10.1074/mcp.m700187-mcp200