Výsledky vyhledávání - "Chengchi Huang"

Akademický článek

Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice

Autor: Chengchi Huang, Liyang Ji, Avinash Kaur, Hong Tian, Prabuddha Waduge, Keith A. Webster, Wei Li

Publikováno v: Biomedicines, Vol 11, Iss 7, p 1910 (2023)

Neovascular age-related macular degeneration (nAMD) with choroidal neovascularization (CNV) is a leading cause of blindness in the elderly in developed countries. The disease is currently treated with anti-angiogenic biologics, including aflibercept,

Externí odkaz: https://doaj.org/article/e8a113c369674d75af4e950bbf65fe41

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Akademický článek

Protective roles of autophagy in retinal pigment epithelium under high glucose condition via regulating PINK1/Parkin pathway and BNIP3L

Autor: Chengchi Huang, Hong Lu, Junyu Xu, Hongmin Yu, Xiaodan Wang, Xiaomei Zhang

Publikováno v: Biological Research, Vol 51, Iss 1, Pp 1-9 (2018)

Abstract Background Our study aimed to investigate the roles of autophagy against high glucose induced response in retinal pigment epithelium (ARPE-19 cells). Methods The morphological changes and reactive oxygen species (ROS) generation in ARPE-19 c

Externí odkaz: https://doaj.org/article/2a32408991c441c5bfc0663b224b8a1d

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Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice

Autor: Li, Chengchi Huang, Liyang Ji, Avinash Kaur, Hong Tian, Prabuddha Waduge, Keith A. Webster, Wei

Publikováno v: Biomedicines; Volume 11; Issue 7; Pages: 1910

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::40ab9e15c4d2e6589111588277f79371

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Secretogranin III Selectively Promotes Vascular Leakage in the Deep Vascular Plexus of Diabetic Retinopathy

Autor: Li, Liyang Ji, Prabuddha Waduge, Yan Wu, Chengchi Huang, Avinash Kaur, Paola Oliveira, Hong Tian, Jinsong Zhang, J. Timothy Stout, Christina Y. Weng, Keith A. Webster, Wei

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10531

Diabetic retinopathy (DR), a leading cause of vision loss in working-age adults, induces mosaic patterns of vasculopathy that may be associated with spatial heterogeneity of intraretinal endothelial cells. We recently reported that secretogranin III

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::497243d8ffc3b87ed7bb55a31e2769bf

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Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy

Autor: Chang Dai, Prabuddha Waduge, Liyang Ji, Chengchi Huang, Ye He, Hong Tian, Elizabeth Zuniga-Sanchez, Amit Bhatt, Iok-Hou Pang, Guanfang Su, Keith A. Webster, Wei Li

Publikováno v: Cell Mol Life Sci

Conventional angiogenic factors, such as vascular endothelial growth factor (VEGF), regulate both pathological and physiological angiogenesis indiscriminately, and their inhibitors may elicit adverse side effects. Secretogranin III (Scg3) was recentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b31354372255d4c03d8b66e8bf78f11
https://europepmc.org/articles/PMC9007175/

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CircFAT1 regulates retinal pigment epithelial cell pyroptosis and autophagy via mediating m6A reader protein YTHDF2 expression in diabetic retinopathy

Autor: Chengchi Huang, Peng Qi, Hao Cui, Qun Lu, Xue Gao

Publikováno v: Experimental eye research. 222

Diabetic retinopathy (DR) is a serious blinding complication of diabetes. At present, the therapeutic intervention effect is limited. We aimed to investigate the circRNA expression profiles in retinal proliferative fibrovascular membranes of patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa60d97a85f0ddec985c230002c603e
https://pubmed.ncbi.nlm.nih.gov/35714699

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Protective roles of autophagy in retinal pigment epithelium under high glucose condition via regulating PINK1/Parkin pathway and BNIP3L

Autor: Xiao-mei Zhang, Chengchi Huang, Xiaodan Wang, Hongmin Yu, Hong Lu, Junyu Xu

Publikováno v: Biological Research
Biological Research v.51 2018
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 51, Iss 1, Pp 1-9 (2018)
Biological Research, Volume: 51, Article number: 22, Published: 03 AUG 2018

Background Our study aimed to investigate the roles of autophagy against high glucose induced response in retinal pigment epithelium (ARPE-19 cells). Methods The morphological changes and reactive oxygen species (ROS) generation in ARPE-19 cells unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f803707dedee2d99c98d0d208a61f93e
https://doi.org/10.1186/s40659-018-0169-4

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Multi-walled boron nitride nanotubes as self-excited launchers

Autor: Hui Li, Zhenyang Zhao, Chengchi Huang, Yi Zhou, Yan Wu, Xuyan Zhou, Long Wang, Yifan Li

Publikováno v: Nanoscale. 9(29)

A self-excited launcher consisting of multi-walled boron nitride nanotubes (BNNTs) has been investigated using molecular dynamics simulation. The results show that, after a period of high frequency oscillation, the innermost BNNT can be spontaneously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b43173add36c9aad4d87770ca6643b
https://pubmed.ncbi.nlm.nih.gov/28702575

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