Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Chengcheng Tang"'
Autor:
Wei Zheng, Jiahui Xi, Yin Zi, Jinling Wang, Yue Chi, Min Chen, Qingjian Zou, Chengcheng Tang, Xiaoqing Zhou
Publikováno v:
Veterinary World, Vol 16, Iss 11, Pp 2374-2381 (2023)
Background and Aim: African swine fever (ASF), a globally transmitted viral disease caused by ASF virus (ASFV), can severely damage the global trade economy. Laboratory diagnostic methods, including pathogen and serological detection techniques, are
Externí odkaz:
https://doaj.org/article/af8eeab620964d33bdb8ad2e483e197b
Autor:
Ting Lan, Huangyao Chen, Chengcheng Tang, Yuhui Wei, Yang Liu, Jizeng Zhou, Zhenpeng Zhuang, Quanjun Zhang, Min Chen, Xiaoqing Zhou, Yue Chi, Jinling Wang, Yu He, Liangxue Lai, Qingjian Zou
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 890-897 (2023)
Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, in vivo implementation of PE remains a challenge because of its oversized composition. In this study, we screened out
Externí odkaz:
https://doaj.org/article/8627ee1167194107a2672a4ab7f37199
Autor:
Meiling Jiang, Chengcheng Tang, Xian Luo, Xiaoqing Zhou, Min Chen, Yue Chi, Liangxue Lai, Qingjian Zou
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103136- (2023)
The RAN Guanine Nucleotide Release Factor (RANGRF) gene encodes the protein MOG1, which binds to Nav1.5 and facilitates its transport to the cell membrane. Nav1.5 mutations have been linked to various cardiac arrhythmias and cardiomyopathy. To invest
Externí odkaz:
https://doaj.org/article/1029adcf0db04dd8bf3d0b1943f9d51a
Autor:
Qin Jin, Xiaoyi Liu, Zhenpeng Zhuang, Jiayuan Huang, Shixue Gou, Hui Shi, Yu Zhao, Zhen Ouyang, Zhaoming Liu, Lei Li, Junjie Mao, Weikai Ge, Fangbing Chen, Manya Yu, Yezhi Guan, Yinghua Ye, Chengcheng Tang, Ren Huang, Kepin Wang, Liangxue Lai
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background CRISPR-based toolkits have dramatically increased the ease of genome and epigenome editing. SpCas9 is the most widely used nuclease. However, the difficulty of delivering SpCas9 and inability to modulate its expression in vivo hin
Externí odkaz:
https://doaj.org/article/110960d35b9b427bbaadfb937e744aa5
Autor:
Yinge Jin, Tao Chen, Wei Zheng, Jiahui Xi, Yin Zi, Jinling Wang, Yue Chi, Min Chen, Qingjian Zou, Chengcheng Tang, Liangxue Lai, Xiaoqing Zhou
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: The ABO blood group system has important clinical significance in the safety of blood transfusion and organ transplantation. Numerous ABO variations, especially variations in the splice sites, have been identified to be associated with
Externí odkaz:
https://doaj.org/article/9827da97f8124a02b6dafab79d58c063
Autor:
Yu Liu, Yinge Jin, Tao Chen, Yunqin Wu, Xiaohua Peng, Wansheng Li, Shu Wei, Min Chen, Qingjian Zou, Suqin Guo, Jucai Xu, Chengcheng Tang, Xiaoqing Zhou
Publikováno v:
Stem Cell Research, Vol 68, Iss , Pp 103021- (2023)
Externí odkaz:
https://doaj.org/article/f85c490ffc2540a4866d43bc1e05ceda
Autor:
Yang Liu, Yang Yang, Yangyang Suo, Chuan Li, Min Chen, Shuwen Zheng, Hao Li, Chengcheng Tang, Nana Fan, Ting Lan, Jizeng Zhou, Yingying Li, Jiaowei Wang, Huangyao Chen, Qingjian Zou, Liangxue Lai
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 332-341 (2022)
Pluripotent stem cells (PSCs) are promising in regenerative medicine. A major challenge of PSC therapy is the risk of teratoma formation because of the contamination of undifferentiated stem cells. Constitutive promoters or endogenous SOX2 promoters
Externí odkaz:
https://doaj.org/article/816ae9b9e7cd405baf12a610222efcf9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
The shortage of donor resources has greatly limited the application of clinical xenotransplantation. As such, genetically engineered pigs are expected to be an ideal organ source for xenotransplantation. Most current studies mainly focus on genetical
Externí odkaz:
https://doaj.org/article/676566ca18304086a230e6d761a0a185
Publikováno v:
World Electric Vehicle Journal, Vol 14, Iss 7, p 172 (2023)
A ramp merging decision as an important part of the lane change model plays a crucial role in the efficiency and safety of the entire merging process. However, due to the inevitability of on-ramp merging, the limitations of the road environment, and
Externí odkaz:
https://doaj.org/article/898614db11b54d7ca3f033126a7b2479
Autor:
Yu Liu, Yinge Jin, Tao Chen, Yunqin Wu, Xiaohua Peng, Wansheng Li, Shu Wei, Min Chen, Qingjian Zou, Suqin Guo, Jucai Xu, Chengcheng Tang, Xiaoqing Zhou
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102764- (2022)
The human specific gene ARHGAP11B is preferentially expressed in neural progenitors of fetal neocortex and plays a key role in the evolutionary expansion of the neocortex. Here, we generated a homozygous ARHGAP11B knockout human induced pluripotent s
Externí odkaz:
https://doaj.org/article/d6e9a57a1da6450fbdbdb6e65f447d58