Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Cheng-xiong Xu"'
Autor:
Hao Luo, Qing Li, Ren-Tao Wang, Liang Zhang, Wei Zhang, Meng-Sheng Deng, Yuan-Yuan Luo, Xintong Ji, Yongheng Wen, Xuan-Rui Zhou, Bo Xu, Dong Wang, Bin Hu, Hua Jin, Cheng-Xiong Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-17 (2023)
Abstract Recurrence is one of the main causes of treatment failure in early-stage non-small cell lung cancer (NSCLC). However, there are no predictors of the recurrence of early-stage NSCLC, and the molecular mechanism of its recurrence is not clear.
Externí odkaz:
https://doaj.org/article/58deed27543349ada6fd8a9eb430d987
Autor:
Qing Li, Hao Luo, Fu‐Qiang Dai, Ren‐Tao Wang, Xiao‐Qing Fan, Yuan‐Yuan Luo, Meng‐Sheng Deng, Yulun Wang, Tan Long, Wei Guo, Bo Xu, Cheng‐Xiong Xu, Hua Jin
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Recurrence is a challenge to survival after the initial treatment of esophageal squamous cell carcinoma (ESCC). But, its mechanism remains elusive and there are currently no biomarkers to predict postoperative recurrence. Here, the possibili
Externí odkaz:
https://doaj.org/article/9223b7359de3419eba1e03fd7b3217fc
Autor:
Qing Li, Zhi-Wei Zhou, Wei Duan, Cheng-Yuan Qian, Shu-Nan Wang, Meng-Sheng Deng, Dan Zi, Jian-Min Wang, Cheng-Yi Mao, Guanbin Song, Dong Wang, Kenneth D. Westover, Cheng-Xiong Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Abstract Background Metastasis is a major challenge in cervical cancer treatment. Previous studies have shown that the dual functional protein apurinic/apyrimidinic endonuclease 1 (APE1) promotes tumor metastasis and is overexpressed in cervical canc
Externí odkaz:
https://doaj.org/article/df0fdbb37153427b9ab12149a6573932
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 627-637 (2019)
Despite surgery and adjuvant therapy, early-stage lung adenocarcinoma (LUAD) treatment often fails due to local or metastatic recurrence. However, the mechanism is largely unknown. Here, we report that increased expression levels of miR-134-5p and de
Externí odkaz:
https://doaj.org/article/64d383e51e544daa891d54806ae5f513
Autor:
Hua Jin, Yoonjeong Jang, Nian Cheng, Qing Li, Peng-Fei Cui, Zhi-Wei Zhou, Hu-Lin Jiang, Myung-Haing Cho, Kenneth D. Westover, Qun-You Tan, Cheng-Xiong Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background miRNAs play crucial role in the progression of K-Ras-mutated nonsmall cell lung cancer (NSCLC). However, most studies have focused on miRNAs that target K-Ras. Here, we investigated miRNAs regulated by mutant K-Ras and their funct
Externí odkaz:
https://doaj.org/article/7b3a3c05b70c4aa2aaa96faea1c11380
Autor:
Hua Jin, Dian-Wei Li, Shu-Nan Wang, Song Luo, Qing Li, Ping Huang, Jian-Min Wang, Meng Xu, Cheng-Xiong Xu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 493-502 (2018)
Giant cell tumors of bone (GCTBs) exhibit high recurrence and aggressive bone lytic behavior; but, the mechanism of GCTB progression is largely unknown. In GCTB, we detected abundant levels of miR-125a, which were associated with tumor extension, gra
Externí odkaz:
https://doaj.org/article/f5b9dfb8c1524659bd42c798b3593ef9
Autor:
Hua Jin, Qing Li, Fenghao Cao, Shu-Nan Wang, Ren-Tao Wang, Yun Wang, Qun-You Tan, Cheng-Run Li, Hua Zou, Dong Wang, Cheng-Xiong Xu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 145-154 (2017)
Dysregulated miRNAs play important role in K-ras mutation or smoking caused lung tumorigenesis. Here, we investigate the role and mechanism of miR-124 in K-ras mutation or smoking-caused lung tumorigenesis and evaluate the therapeutic potential of mi
Externí odkaz:
https://doaj.org/article/3bdf04390aa74de0be244bcdbeedc076
Autor:
Hua Jin, Song Luo, Yun Wang, Chang Liu, Zhenghao Piao, Meng Xu, Wei Guan, Qing Li, Hua Zou, Qun-You Tan, Zhen-Zhou Yang, Yan Wang, Dong Wang, Cheng-Xiong Xu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 111-122 (2017)
Cancer stem cells (CSCs) play an important role in osteosarcoma (OS) metastasis and recurrence, and both Wnt/β-catenin and Notch signaling are essential for the development of the biological traits of CSCs. However, the mechanism that underlies the
Externí odkaz:
https://doaj.org/article/5b68f72969ad4fd7bb689a94d13b6010
Autor:
Yong-Cheng Jin, Jeng-A Han, Cheng-Xiong Xu, Sang-Kee Kang, Sang-Hun Kim, Kang-Suk Seo, Du-Hak Yoon, Yun-Jaie Choi, Hong-Gu Lee
Publikováno v:
BMB Reports, Vol 45, Iss 2, Pp 102-107 (2012)
The aim of this study was to investigate protein profiles relatedto the induction of adipogenesis within the bovine longissimusdorsi muscle (BLDM) by proteomic analysis. We analyzedBLDM proteins at different growth stages to clarify the physiological
Externí odkaz:
https://doaj.org/article/6a347c0bbbe94d2394d45e77d81e751b
Autor:
Cheng-Xiong Xu, Yikun Li, Ping Yue, Taofeek K Owonikoko, Suresh S Ramalingam, Fadlo R Khuri, Shi-Yong Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20899 (2011)
The phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) signaling axis has emerged as a novel target for cancer therapy. Agents that inhibit PI3K, mTOR or both are currently under development. The mTOR allosteric inhibitor, RAD001,
Externí odkaz:
https://doaj.org/article/b55318a8eeed457189e4666ebde8fa60