Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Cheng-peng Sun"'
Autor:
Juan Zhang, Min Zhang, Qi-Meng Zhu, Xin-Rong Xu, Yan-Li Feng, Sheng Lin, Feng Qiu, Cheng-Peng Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4174-4178 (2024)
Externí odkaz:
https://doaj.org/article/be1768229edc4b0dbbaf9455295d5d50
Autor:
Wei Pan, Lei Feng, Cheng-Peng Sun, Xiang-Ge Tian, Chao Shi, Chao Wang, Xia Lv, Yan Wang, Shan-Shan Huang, Bao-Jing Zhang, Jing Ning, Xiao-Chi Ma
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 10, Pp 105156- (2023)
The interaction between herbs and clinical drugs is one of the risk factors for adverse drug reactions. In the present study, the inhibitory effects of 47 tetracyclic triterpenoids toward the main drug-metabolizing CYPs in humans were investigated. M
Externí odkaz:
https://doaj.org/article/c045e2b969e046859cd83bc06f880791
Autor:
Jing-Xin Li, Yu Wang, Ying Hao, Xiao-Kui Huo, Cheng-Peng Sun, Xiao-Xia Zhao, Jin-Cheng Wang, Jian-Bin Zhang, Jing Ning, Xiang-Ge Tian, Chao Wang, Wen-Yu Zhao, Xia Lv, Ya-Chen Li, Xiao-Chi Ma
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2023)
Abstract Gut bacterial β-glucuronidase (GUS) can reactivate xenobiotics that exert enterohepatic circulation- triggered gastrointestinal tract toxicity. GUS inhibitors can alleviate drug-induced enteropathy and improve treatment outcomes. We evaluat
Externí odkaz:
https://doaj.org/article/a22531c0e2d247c2ac761d3ba7979130
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/769c1c0eed334c5992c7f0ea108dd0cd
Autor:
Bo Wang, Chao Shi, Lei Feng, Wei Pan, Xiang-Ge Tian, Cheng-Peng Sun, Chao Wang, Jing Ning, Xia Lv, Yan Wang, Qian-Hui Yuan, Rui-Xuan Guan, Hou-Li Zhang, Xiao-Chi Ma, Tong-Hui Ma
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
CYP3A4-mediated Phase I biotransformation is the rate-limiting step of elimination for many commonly used clinically agents. The modulatory effects of herbal medicines on CYP3A4 activity are one of the risk factors affecting the safe use of drug and
Externí odkaz:
https://doaj.org/article/dc263f9bd72a4cbcbb95f2fcaf3d6682
Autor:
Cheng-Peng Sun, Xiang-Ge Tian, Lei Feng, Chao Wang, Jing-Xin Li, Xiao-Kui Huo, Wen-Yu Zhao, Jing Ning, Zhen-Long Yu, Sa Deng, Bao-Jing Zhang, Xia Lv, Jie Hou, Xiao-Chi Ma
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 12, Pp 103457- (2021)
Gut bacterial β-glucuronidase is regarded as an important molecular target for several therapeutic applications. Inhibitors of β-glucuronidase can effectively alleviate the drug-induced gastrointestinal tract toxicity. In this study, the ethanol ex
Externí odkaz:
https://doaj.org/article/99f3e1c8597e440ba0d673c8006141b0
Autor:
Yu-Long Lan, Jun-Jun Zhou, Jing Liu, Xiao-Kui Huo, Ya-Li Wang, Jia-Hao Liang, Jian-Chao Zhao, Cheng-Peng Sun, Zhen-Long Yu, Lin-Lin Fang, Xiang-Ge Tian, Lei Feng, Jing Ning, Bao-Jing Zhang, Chao Wang, Xin-Yu Zhao, Xiao-Chi Ma
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 4, Pp 1453-1464 (2018)
Background/Aims: Uncaria rhynchophylla, known as “Gou-teng”, is a traditional Chinese medicine (TCM) used to extinguish wind, clear heat, arrest convulsions, and pacify the liver. Although U. rhynchophylla has a long history of being often used t
Externí odkaz:
https://doaj.org/article/c4d4716917f042e396e1949103448819
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Five new physalins, including a novel 1,10-seco one, physalin V (1), a tricarboxylic acid cycle one, physalin VIII (5), a rare 11,15-cyclo one, physalin IX (6), and two new ones, physalins VI (2) and VII (4) were isolated from stems and leav
Externí odkaz:
https://doaj.org/article/1df34b5b66ac4afdb963793b46751111
Autor:
Juan Zhang, Min Zhang, Xiao-Kui Huo, Jing Ning, Zhen-Long Yu, Christophe Morisseau, Cheng-Peng Sun, Bruce D. Hammock, Xiao-Chi Ma
Publikováno v:
ACS central science, vol 9, iss 3
Soluble epoxide hydrolase (sEH) plays a critical role in inflammation by modulating levels of epoxyeicosatrienoic acids (EETs) and other epoxy fatty acids (EpFAs). Here, we investigate the possible role of sEH in lipopolysaccharide (LPS)-mediated mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4dc624fc9d495fb8da915803b75d52
https://doi.org/10.1021/acscentsci.2c01424
https://doi.org/10.1021/acscentsci.2c01424
Autor:
Min, Zhang, Juan, Zhang, Qi-Meng, Zhu, Wen-Yu, Zhao, Xia, Lv, Jing, Yi, Xiao-Kui, Huo, Mi-Jia, Wang, Cheng-Peng, Sun
Publikováno v:
Journal of Pharmacy and Pharmacology. 75:287-299
Objectives To investigate the protective effect and underlying mechanism of Inula japonica (TEIJ) in the treatment of acute lung injury (ALI). Methods Protective effects of TEIJ in the inflammation and oxidative stress were studied in lipopolysacchar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f310669ba88509af718863ce96fcd25f
https://doi.org/10.1093/jpp/rgac084
https://doi.org/10.1093/jpp/rgac084