Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Cheng-Yu Gu"'
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Akademický článek
α-Fetoprotein promoter-driven Cre/LoxP-switched RNA interference for hepatocellular carcinoma tissue-specific target therapy.
Autor: Yuan-Fei Peng, Ying-Hong Shi, Zhen-Bin Ding, Jian Zhou, Shuang-Jian Qiu, Bo Hui, Cheng-Yu Gu, Hua Yang, Wei-Ren Liu, Jia Fan
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e53072 (2013)
RNA interference (RNAi) has recently emerged as a potential treatment modality for hepatocellular carcinoma (HCC) therapy, but the lack of cellular targets and sustained efficacy limits its application. The purpose of this study is to develop an HCC
Externí odkaz: https://doaj.org/article/119a85e961f94570add8dc8c2dcfe790
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2
Synthesis of Sulfonylated Cinchona Alkaloids via Zinc-Mediated Sulfonylation of the N-Oxides of the Quinoline Groups
Autor: Fu-She Han, Jie Zhou, Cheng-Yu Gu
Publikováno v: Synthesis. 54:4810-4817
A general and practical method for the synthesis of sulfonylated cinchona alkaloids is presented. The reactions are carried out via Zn-mediated nucleophilic aromatic substitution of the N-oxides of the quinoline core in cinchona alkaloids with a rang
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9161509bbb8daeeea4cd6f3297254129
https://doi.org/10.1055/a-1900-0293
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6
Data from Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation
Autor: Jia Fan, Ying-Hao Shen, Zhi Dai, Kang Song, Xiao-Ying Wang, Ai-Wu Ke, Guo-Ming Shi, Hua Yang, Cheng-Yu Gu, Yuan-Fei Peng, Jian Zhou, Ying-Hong Shi, Bo Hui, Zhen-Bin Ding
Purpose: Understanding the roles of mammalian autophagy in cancer highlights recent advances in the pharmacologic manipulation of autophagic pathways as a therapeutic strategy for cancer. However, autophagy status and corresponding functions in hepat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5919740d454f48f4bd001e0ff99839d9
https://doi.org/10.1158/1078-0432.c.6519696
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8
Analysis free surface of nonlinear seepage using the MQRBF method
Autor: Yan SU, Zhi-ming ZHENG, Cheng-yu GU, Long-teng ZHANG
Publikováno v: E3S Web of Conferences, Vol 233, p 03042 (2021)
In order to solve the characteristics of low accuracy and slow efficiency in traditional numerical solution the free surface problem, the multiquardatic radial base function collocation method(MQ RBF) is used to analyze the constant seepage and unste
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f7388f04955e36666fff0112d8f0e9
https://doi.org/10.1051/e3sconf/202123303042
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9
Targeting SHCBP1 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma Cells
Autor: Bing Cai, Min Dai, Cheng-Yu Gu, Qun Wang, Haixiao Wang, Ze-Guang Han, Han-chuan Tao
Publikováno v: Asian Pacific Journal of Cancer Prevention. 14:5645-5650
Src homology 2 domain containing (SHC) is a proto-oncogene which mediates cell proliferation and carcinogenesis in human carcinomas. Here, the SHC SH2-domain binding protein 1 (SHCBP1) was first established to be up-regulated in human hepatocellular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45923ba2e5af0d587e5ce92271ca571d
https://doi.org/10.7314/apjcp.2013.14.10.5645
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10
Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells
Autor: Shuang-Jian Qiu, Zhen-Bin Ding, Yuan-Fei Peng, Jian Zhou, Ying-Hong Shi, Zhi Dai, Jia Fan, Ai-Wu Ke, Bo Hui, Cheng-Yu Gu
Publikováno v: Autophagy. 9(12)
Metastasis is one of the main causes of poor prognosis for hepatocellular carcinoma (HCC), which has been linked to cell-death resistance. Autophagy is an important survival mechanism under conditions of cell stress. We hypothesized that autophagy ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebecd23a3cec819ff530bc29860020c
https://pubmed.ncbi.nlm.nih.gov/24157892
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