Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Cheng-Su Xu"'
Autor:
Marshall A. Corson, Tracy Tylee, Xue Han Ning, Yong Kian Soh, Ming Ge, Lu Ping Fan, David Anderson, Lin Yao, Shi Han Chen, Outi M. Villet, Norman E. Buroker, Michael A. Portman, Cheng Su Xu, Aaron K. Olson, Elise Wang, Laigam N. Sekhar, Chun Zhu
Publikováno v:
Therapeutic Hypothermia and Temperature Management. 5:40-47
Many therapeutic hypothermia recommendations have been reported, but the information supporting them is sparse, and reveals a need for the data of target therapeutic hypothermia (TTH) from well-controlled experiments. The core temperature ≤35°C is
Autor:
Ying Tzang Tien, Shi Han Chen, Xue Han Ning, Cheng Su Xu, Ming Ge, Michael A. Portman, Norman E. Buroker, Emil Y. Chi, Outi M. Hyyti
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H2119-H2128
Hypothermia preserves myocardial function, promotes signaling for cell survival, and inhibits apoptotic pathways during 45-min reperfusion. We tested the hypothesis that signaling at the transcriptional level is followed by corresponding proteomic re
Autor:
Shi Han Chen, Cheng Su Xu, Kun Qian, Michael A. Portman, Julia J. Krueger, Outi M. Hyyti, Xue Han Ning
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 285:H212-H219
Hypothermia before and/or during no-flow ischemia promotes cardiac functional recovery and maintains mRNA expression for stress proteins and mitochondrial membrane proteins (MMP) during reperfusion. Adaptation and protection may occur through cold-in
Autor:
Kun Qian, Outi M. Hyyti, Lena Y. Yao, Shi-Han Chen, Xue-Han Ning, Linheng Li, Cheng-Su Xu, Michael A. Portman, Julia J. Krueger
Publikováno v:
Journal of Applied Physiology. 92:2200-2207
Hypothermia improves resistance to ischemia in the cardioplegia-arrested heart. This adaptive process produces changes in specific signaling pathways for mitochondrial proteins and heat-shock response. To further test for hypothermic modulation of ot
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 277:R11-R17
Hypothermia improves resistance to subsequent ischemia in the cardioplegic-arrested heart (CAH). This adaptive process produces mRNA elevation for heat shock protein (HSP) 70–1 and mitochondrial proteins, adenine nucleotide translocator (ANT1), and
Autor:
Ying C. Song, Cheng Su Xu, Michael A. Portman, Xue Han Ning, Yun Xiao, Flavian M. Lupinetti, Ying Jia Hu
Publikováno v:
Cryobiology. 36:321-329
Temperature modulates both myocardial energy requirements and production. We have previously demonstrated that myocardial protection induced by hypothermic adaptation preserves expression of genes regulating heat shock protein and the nuclear-encoded
Hypothermia preserves function and signaling for mitochondrial biogenesis during subsequent ischemia
Autor:
Cheng Su Xu, Xue Han Ning, Flavian M. Lupinetti, Ying Jia Hu, Yun Xiao, Ying C. Song, Michael A. Portman
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 274:H786-H793
Hypothermia is known to protect myocardium during ischemia, but its role in induction of a protective stress response before ischemia has not been evaluated. As cold incites stress responses in other tissues, including heat shock protein induction an
Autor:
Steven F. Bolling, Cheng Su Xu, Flavian M. Lupinetti, Michael A. Portman, Yun Xiao, Xue Han Ning, Keith F. Childs, Ying C. Song
Publikováno v:
Cryobiology. 36:2-11
Hypothermia protects ischemic tissues by reducing ATP utilization and accumulation of harmful metabolites. However, it also reduces ATP production, which might cause deterioration in the energy supply/demand ratio. Modulation of energy supply/demand
Autor:
David Peebles, Chris W. Gardner, Alan H. Jobe, Lin Zhao, P. Gaudreau, Gideon Koren, Kristina Bry, Machiko Ikegami, Gore Ervin, Julia A. Klein, Gustav Schonfeld, K. Adamovits, Stanley M. Berry, G. Gyódi, Zoltán Nyúl, Mikko Hallman, George A. Emerson, Mickey A. Latour, Wolfgang Rascher, C. Farmer, Heide T. Moore, Endre Sulyok, Stefan Worgall, Cheng Su Xu, Franca Ursitti, James N. Jarvis, Norihisa Wada, Z. Baranyai
Publikováno v:
Neonatology. 72:I-IV
Publikováno v:
Neonatology. 72:329-336
Fetal and neonatal lymphocytes are relatively resistant to activation and cytokine production when stimulated either via their T-cell antigen receptors or lectins. The molecular mechanism(s) responsible for this phenomenon have not been clearly eluci