Synthesis of (-)-Cannabidiol (CBD), (-)-Δ ⁹ - and (-)-Δ ⁸ -Tetrahydrocannabinols, Encapsulation of CBD with Nanoparticles for Controlled Delivery and Biological Evaluation.

Autor: Moya-Utrera F; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Fuentes-Ríos D; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Romero-Carrasco A; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Doña-Flores M; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Cheng-Sánchez I; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland., Díaz-Morilla A; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Soledad Pino-González M; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., Martínez-Ferez A; Department of Chemical Engineering, University of Granada, 18012, Granada, Spain., Moreno J; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain., Mesas C; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain.; Instituto de Investigación Biosanitaria ibs. Granada, 18012, Granada, Spain.; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18071, Granada, Spain., Melguizo C; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain.; Instituto de Investigación Biosanitaria ibs. Granada, 18012, Granada, Spain.; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18071, Granada, Spain., Prados J; Institute of Biopathology and Regenerative Medicine (IBIMER), Center of Biomedical Research (CIBM), University of Granada, 18100, Granada, Spain.; Instituto de Investigación Biosanitaria ibs. Granada, 18012, Granada, Spain.; Department of Anatomy and Embryology, Faculty of Medicine, University of Granada, 18071, Granada, Spain., Sarabia F; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain., López-Romero JM; Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus de Teatinos, s/n, 29071, Málaga, Spain.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Sep 22, pp. e202402496. Date of Electronic Publication: 2024 Sep 22.

Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain.

Autor: Cheng-Sánchez I; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Gosselé KA; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.; Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Palaferri L; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Kirillova MS; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland., Nevado C; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Jan 26; Vol. 15 (3), pp. 355-361. Date of Electronic Publication: 2024 Jan 26 (Print Publication: 2024).

Dual Nickel/Photoredox-Catalyzed Asymmetric Carbosulfonylation of Alkenes.

Autor: Du X; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland., Cheng-Sánchez I; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland., Nevado C; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, Zurich, CH 8057, Switzerland.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2023 Jun 14; Vol. 145 (23), pp. 12532-12540. Date of Electronic Publication: 2023 May 30.

Characterization of the activity and the mechanism of action of a new toluquinol derivative with improved potential as an antiangiogenic drug.

Autor: Torres-Vargas JA; Department of Molecular Biology and Biochemistry, University of Malaga, Andalucía Tech, Málaga, Spain; IBIMA (Biomedical Research Institute of Malaga)-BIONAND Platform, University of Málaga, Andalucía Tech, Málaga, Spain., Cheng-Sánchez I; Department of Organic Chemistry, University of Malaga, Andalucía Tech, Spain., Martínez-Poveda B; Department of Molecular Biology and Biochemistry, University of Malaga, Andalucía Tech, Málaga, Spain; CIBER de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Medina MÁ; Department of Molecular Biology and Biochemistry, University of Malaga, Andalucía Tech, Málaga, Spain; IBIMA (Biomedical Research Institute of Malaga)-BIONAND Platform, University of Málaga, Andalucía Tech, Málaga, Spain; U741 (CB06/07/0046) CIBERER, Malaga, Spain., Sarabia F; Department of Organic Chemistry, University of Malaga, Andalucía Tech, Spain., García-Caballero M; Department of Molecular Biology and Biochemistry, University of Malaga, Andalucía Tech, Málaga, Spain; IBIMA (Biomedical Research Institute of Malaga)-BIONAND Platform, University of Málaga, Andalucía Tech, Málaga, Spain. Electronic address: melissa@uma.es., Quesada AR; Department of Molecular Biology and Biochemistry, University of Malaga, Andalucía Tech, Málaga, Spain; IBIMA (Biomedical Research Institute of Malaga)-BIONAND Platform, University of Málaga, Andalucía Tech, Málaga, Spain; U741 (CB06/07/0046) CIBERER, Malaga, Spain. Electronic address: quesada@uma.es.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113759. Date of Electronic Publication: 2022 Sep 30.

The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria.

Autor: Porras-Alcalá C; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., Moya-Utrera F; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., García-Castro M; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., Sánchez-Ruiz A; Faculty of Pharmacy, Campus de Albacete, Universidad de Castilla-La Mancha, 02008 Albacete, Spain., López-Romero JM; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., Pino-González MS; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., Díaz-Morilla A; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain., Kitamura S; Department of Molecular Medicine, The Scripps Research Institute, San Diego, CA 92037, USA.; Department of Biochemistry, Albert Einstein College of Medicine, New York, NY 10641, USA., Wolan DW; Department of Molecular Medicine, The Scripps Research Institute, San Diego, CA 92037, USA., Prados J; Center of Biomedical Research (CIBM), Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, 18100 Granada, Spain.; Department of Anatomy and Embriology, Faculty of Medicine, University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria ibs, Granada, 18012 Granada, Spain., Melguizo C; Center of Biomedical Research (CIBM), Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, 18100 Granada, Spain.; Department of Anatomy and Embriology, Faculty of Medicine, University of Granada, 18071 Granada, Spain.; Instituto de Investigación Biosanitaria ibs, Granada, 18012 Granada, Spain., Cheng-Sánchez I; Department of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland., Sarabia F; Department of Organic Chemistry, Faculty of Sciences, University of Malaga, 29071 Málaga, Spain.

Publikováno v: Marine drugs [Mar Drugs] 2022 May 31; Vol. 20 (6). Date of Electronic Publication: 2022 May 31.