Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Cheng-Rong Xiao"'
Autor:
Pan Shen, Zhi-Jie Bai, Lei Zhou, Ning-Ning Wang, Zhe-Xin Ni, De-Zhi Sun, Cong-Shu Huang, Yang-Yi Hu, Cheng-Rong Xiao, Wei Zhou, Bo-Li Zhang, Yue Gao
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 806-816 (2023)
Hepatotoxicity induced by bioactive constituents in traditional Chinese medicines or herbs, such as bavachin (BV) in Fructus Psoraleae, has a prolonged latency to overt drug-induced liver injury in the clinic. Several studies have described BV-induce
Externí odkaz:
https://doaj.org/article/61adaaf4e40c41b088610b4f952c1755
Autor:
Yun-Xuan Ge, Zhuo Zhang, Jia-Yi Yan, Zeng-Chun Ma, Yu-Guang Wang, Cheng-Rong Xiao, Xiao-Mei Zhuang, Yue Gao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3047 (2024)
E0703, a new steroidal compound optimized from estradiol, significantly increased cell proliferation and the survival rate of KM mice and beagles after ionizing radiation. In this study, we characterize its preclinical pharmacokinetics (PK) and predi
Externí odkaz:
https://doaj.org/article/0ce09827aec2489aadb627f93a4ca80d
Autor:
Zhuo Shi, Jin-Chao Pan, Cheng Zhang, Jia-Lu Cui, Xiang-Jun Wu, Fang-Yang Li, Mao-Xing Li, Cheng-Rong Xiao, Zeng-Chun Ma, Yu-Guang Wang, Yue Gao
Publikováno v:
Acupuncture & Herbal Medicine; Jun2024, Vol. 4 Issue 2, p234-242, 9p
Autor:
Cheng-Rong Xiao, Panpan Ruan, Jing Gao, Gao Yue, Yunxuan Ge, Quansheng Gao, Jiayi Yan, Hong-Ling Tan, Zhuo Zhang
Publikováno v:
ACS Omega, Vol 6, Iss 41, Pp 26942-26951 (2021)
ACS Omega
ACS Omega
Compound Danshen dropping pill (CDDP), a famous Chinese medicine formula, has been widely used to treat high-altitude heart disease in China. However, its molecular mechanisms, potential targets, and bioactive ingredients remain elusive. In this stud
Autor:
Ning-Ning Wang, Cheng-Rong Xiao, Cong-Shu Huang, Yue Gao, Hong Liu, Yuguang Wang, Lan-Xin Yue, Yu-Hao Ni, Xian Liu, Hui-Fang Deng, Yong-Qiang Zhou, Li-Zhen Qiu, Wei Zhou
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Cassiae Semen is a widely used herbal medicine and a popular edible variety in many dietary or health beverage. Emerging evidence disclosed that improper administration of Cassiae Semen could induce obvious liver injury, which is possibly attributed
Autor:
Xianglin Tang, Cheng-Rong Xiao, Yue Gao, Hong-Ling Tan, Haiyan Zhu, Zengchun Ma, Yuguang Wang, Boli Zhang, Zhi-Wu Chen
Publikováno v:
Biomolecules & Therapeutics
Tanshinone IIA (Tan IIA) is a pharmacologically active substance extracted from the rhizome of Salvia miltiorrhiza Bunge (also known as the Chinese herb Danshen), and is widely used to treat atherosclerosis. The pregnane X receptor (PXR) is a nuclear
Autor:
Cheng-Rong Xiao, Mei-Xi Wang, Tang Xianglin, Xu Huanhua, Ma Zengchun, Hao Feiran, Ming Li, Qiande Liang, Wang Yuguang, Gao Yue, Si-Jia Ren, Hong-Ling Tan
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
The purpose of this work was to study the influences of Realgar-Indigo naturalis(RIF) and its principal element realgar on 4 main cytochrome P450 enzymes activities in rats. A simple and efficient cocktail method was developed to detect the four prob
Autor:
Yue Gao, Qiande Liang, Cheng-Rong Xiao, Hong-Ling Tan, Zengchun Ma, Yuguang Wang, Xianglin Tang, Ya-xin Zhang
Publikováno v:
Biomolecules & Therapeutics
Doxorubicin (DOX) is a highly effective chemotherapeutic agent; however, the dose-dependent cardiotoxicity associated with DOX significantly limits its clinical application. In the present study, we investigated whether Rb1 could prevent DOX-induced
Autor:
Xiang-lin Tang, Zeng-Chun Ma, Wen-ting You, Yu-Guang Wang, Cheng-Rong Xiao, Hong-Ling Tan, Boli Zhang, Tao Zhou, Qiande Liang, Yue Gao
Publikováno v:
Acta Pharmacol Sin
CYP2J3 in myocardium metabolizes arachidonic acid to 4 regioisomeric epoxyeicosatrienoic acids (EETs), which have diverse biological activities in rat heart. In this study we examined whether CYP2J3 was involved in cardioprotective effects of ophiopo
Autor:
Cheng-Rong Xiao, Hong-Ling Tan, Tao Zhou, Zeng-Chun Ma, Wen-ting You, Xiang-lin Tang, Yue Gao, Yu-Guang Wang, Boli Zhang, Qiande Liang
Publikováno v:
Acta Pharmacologica Sinica. 37:177-186
Pregnane X receptor (PXR) is a nuclear receptor that regulates a number of genes encoding drug metabolism enzymes and transporters and plays a key role in xeno- and endobiotic detoxification. Ginkgolide B has shown to increase the activity of PXR. He