Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cheng-Peow Tan"'
Autor:
Zhengyi Li, Haiyan Xu, Jiaqun Li, Xiao Xu, Junjiao Wang, Danya Wu, Jiateng Zhang, Juan Liu, Ziwei Xue, Guankai Zhan, Bobby Cheng Peow Tan, Di Chen, Yun-Shen Chan, Huck Hui Ng, Wanlu Liu, Chih-Hung Hsu, Dan Zhang, Yang Shen, Hongqing Liang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Acquisition of new stem cell fates relies on the dissolution of the prior regulatory network sustaining the existing cell fates. Currently, extensive insights have been revealed for the totipotency regulatory network around the zygotic genom
Externí odkaz:
https://doaj.org/article/35b1d34d886b45658cb76ff50e98280b
Autor:
Yun S. Chan, Bobby Cheng Peow Tan, Huck H. Ng, Andrew C.A. Wan, Yihua Loo, Iwona Szczerbinska, Charlotte A. E. Hauser
Publikováno v:
ACS Applied Bio Materials. 2:1406-1412
Clinical applications of human pluripotent stem cells (PSCs) are limited by the lack of chemically well-defined scaffolds for cell expansion, differentiation, and implantation. In this study, we systematically screened various self-assembling hexapep
Autor:
Hongqing Liang, Jonathan Göke, Cheng Peow Tan, Huck-Hui Ng, Yun-Shen Chan, Giulia Rancati, Kevin Andrew Uy Gonzales, Iwona Szczerbinska, Cheng Kit Wong, Bertha Pei Ge Lee, Engin Cukuroglu, Muhammad Nadzim Bin Ramli
Publikováno v:
Stem Cell Reports
Summary The distinct states of pluripotency in the pre- and post-implantation embryo can be captured in vitro as naive and primed pluripotent stem cell cultures, respectively. The study and application of the naive state remains hampered, particularl
Autor:
Yun-Shen Chan, Yang Shen, Sidika Tapsin, Tong Zhang, Miao Sun, Zhiyan Fu, Cheng-Peow Tan, Yue Wan, Adelene Y. L. Sim, Teodorus Theo Susanto, Kum-Loong Boon, Niranjan Nagarajan, Xin Ni Lim, Andreas Wilm, Jong Ghut Ashley Aw
Publikováno v:
Molecular Cell. 62:603-617
Identifying pairwise RNA-RNA interactions is key to understanding how RNAs fold and interact with other RNAs inside the cell. We present a high-throughput approach, sequencing of psoralen crosslinked, ligated, and selected hybrids (SPLASH), that maps
Autor:
Ka Man Yu, Yun-Shen Chan, Huck-Hui Ng, John Soon Yew Lim, Lai Ping Yaw, Chaiyaboot Ariyachet, Deniz Demircioğlu, Chwee Tat Koe, Yee Siang Lim, Einsi Lynn Soe, Hongqing Liang, Kevin Andrew Uy Gonzales, Nur Halisah Binte Jumat, Yock Young Dan, Iwona Szczerbinska, Shu Hui Koh, Zhiping Lu, Cheng Peow Tan, Asim Shabbir, Graham D. Wright, Wei-Quan Tng, Muhammad Nadzim Bin Ramli
Publikováno v:
Gastroenterology. 159:1471-1486.e12
Background & Aims There are few in vitro models for studying the 3-dimensional interactions among different liver cell types during organogenesis or disease development. We aimed to generate hepatic organoids that comprise different parenchymal liver
Autor:
Jing Ping Tang1, Cheng Peow Tan1, Jie Li1, Siddique, Md Monowarul2, Ke Guo1, Siew Wee Chan1, Jung Eun Park1, Wan Ngee Tay1, Zhi Yuan Huang1, Wen Cai Li3, Jian Chen3, Qi Zeng1 mcbzengq@imcb.a-star.edu.sg
Publikováno v:
Molecular Cancer. 2010, Vol. 9, p128-136. 9p.
Autor:
Leah A. Vardy, Haihe Wang, Jianbiao Zhou, Cheng Peow Tan, Wee Joo Chng, Seng Gee Lim, Ke Guo, Qi Zeng, Jie Li, Jia Min Loo, Hui Xiang Li, Siok Bian Ng
Publikováno v:
Cancer Cell. 18(1):52-62
Summary Overexpression of phosphatase of regenerating liver (PRL)-3 is associated with the progression of diverse human cancers. We show that the overexpression of PRL-3 protein is not directly associated with its transcript levels, indicating the ex
Autor:
Yih-Cherng Liou, Yun-Shen Chan, Huck-Hui Ng, Beilin Le, Hongqing Liang, Bin Gao, Zi-Ying Tan, Kevin Andrew Uy Gonzales, Jia-Chi Yeo, Kok-Yao Low, Yee-Siang Lim, Cheng-Peow Tan, Frederic Bard
Publikováno v:
Cell. 162(3)
During differentiation, human embryonic stem cells (hESCs) shut down the regulatory network conferring pluripotency in a process we designated pluripotent state dissolution (PSD). In a high-throughput RNAi screen using an inclusive set of differentia
Autor:
Qiang Wu, Bo Feng, Monica Fedele, Hu Li, Jin Rong Ow, Yuin-Han Loh, Ziyi Goh, Bobby Cheng Peow Tan, Hui Ma
Publikováno v:
Scientific Reports
Scientific reports (Nature Publishing Group) 4 (2014). doi:10.1038/srep07519
info:cnr-pdr/source/autori:Ma, Hui; Ow, Jin Rong; Tan, Bobby Cheng Peow; Goh, Ziyi; Feng, Bo; Loh, Yuin Han; Fedele, Monica; Li, Hu; Wu, Qiang/titolo:The dosage of Patz1 modulates reprogramming process/doi:10.1038%2Fsrep07519/rivista:Scientific reports (Nature Publishing Group)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume:4
Scientific reports (Nature Publishing Group) 4 (2014). doi:10.1038/srep07519
info:cnr-pdr/source/autori:Ma, Hui; Ow, Jin Rong; Tan, Bobby Cheng Peow; Goh, Ziyi; Feng, Bo; Loh, Yuin Han; Fedele, Monica; Li, Hu; Wu, Qiang/titolo:The dosage of Patz1 modulates reprogramming process/doi:10.1038%2Fsrep07519/rivista:Scientific reports (Nature Publishing Group)/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume:4
The acquisition of pluripotent cells can be achieved by combined overexpression of transcription factors Oct4, Klf4, Sox2 and c-Myc in somatic cells. This cellular reprogramming process overcomes various barriers to re-activate pluripotency genes and
Autor:
Huck-Hui Ng, Jia-Hui Ng, Cheng-Peow Tan, Yee-Siang Lim, Xinyi Lu, Wei-Quan Tng, Jonathan Göke, Zhong-Zhi Hong, Yun-Shen Chan, Kevin Andrew Uy Gonzales
Publikováno v:
Cell stem cell. 13(6)
SummaryHuman embryonic stem cells (hESCs) are derived from the inner cell mass of the blastocyst. Despite sharing the common property of pluripotency, hESCs are notably distinct from epiblast cells of the preimplantation blastocyst. Here we use a com