Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Cheng-Hui Hsiao"'
Autor:
Rahul A. Sheth, Xiaoxia Wen, Junjie Li, Marites P. Melancon, Xin Ji, Y. Andrew Wang, Cheng-Hui Hsiao, Diana S.-L. Chow, Elizabeth M. Whitley, Chun Li, Sanjay Gupta
Publikováno v:
Cancer Nanotechnology, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Doxorubicin-loaded hollow gold nanospheres (Dox@HAuNS) are a promising technology for simultaneous trans-arterial tumor-targeted chemotherapy delivery and thermal ablation. We evaluated the efficacy of intra-arterial delivery of D
Externí odkaz:
https://doaj.org/article/fc608bb790744ab18ce8eb0c052fa93d
Autor:
Cheng-Hui Hsiao, 蕭正輝
96
BACKGROUND: Biliary atresia is the most common cause of death from liver disease in children. Although the Kasai operation before 60 days of age can significantly improve prognosis, delay in referral and surgery remains a formidable problem w
BACKGROUND: Biliary atresia is the most common cause of death from liver disease in children. Although the Kasai operation before 60 days of age can significantly improve prognosis, delay in referral and surgery remains a formidable problem w
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/09809462991588719941
Autor:
Victoria Gershuny, Qin Sun, Sarah J. Schrieber, Murali K. Matta, James L. Weaver, Ping Ji, Morasa Sheikhy, Cheng‐Hui Hsiao, Giri Vegesna, Aanchal Shah, Kristin Prentice, Jennifer Deering, Yow‐Ming Wang, David G. Strauss, Jeffry Florian
Publikováno v:
Clinical pharmacology and therapeutics. 113(1)
The US Food and Drug Administration (FDA) guidance describes how pharmacodynamic (PD) biomarkers can be used to address residual uncertainty and demonstrate no clinically meaningful differences between a proposed biosimilar and its reference product
Autor:
Jeffry Florian, Victoria Gershuny, Qin Sun, Sarah J. Schrieber, Murali K. Matta, Anthony Hazel, Morasa Sheikhy, James L. Weaver, Paula L. Hyland, Cheng‐Hui Hsiao, Giri Vegesna, Ryan DePalma, Aanchal Shah, Kristin Prentice, Carlos Sanabria, Yow‐Ming Wang, David G. Strauss
Publikováno v:
Clinical pharmacology and therapeutics.
The US Food and Drug Administration (FDA) has taken steps to bring efficiency to the development of biosimilars, including establishing guidance for the use of pharmacokinetic and pharmacodynamic (PD) similarity study data without a comparative clini
Autor:
Cheng-Hui Hsiao, Vikram Patel, Insook Kim, Liang Zhao, David G. Strauss, Murali K. Matta, Rodney Rouse, Miyoung Yoon, Ryan DePalma, Victoria Gershuny, Jeffry Florian, Robbert Zusterzeel, David A. Keire, Kristin W. Prentice, Sojeong Yi, Colleen Gosa Nalepinski, Joyce Korvick, Susan Selaya
Publikováno v:
JAMA
Importance In 2019, the US Food and Drug Administration (FDA) received a citizen petition indicating that ranitidine contained the probable human carcinogenN-nitrosodimethylamine (NDMA). In addition, the petitioner proposed that ranitidine could conv
Publikováno v:
International Journal of Nanomedicine. 14:3799-3817
Background and aim: We have synthesized a novel lactone-stabilized camptothecin (CPT) analog named CZ48 and demonstrated its potent anticancer effects via bioconversion to the active CPT in earlier studies. Herein, we aimed to develop, optimize and c
Autor:
Chun Li, Sanjay Gupta, Rahul A. Sheth, Cheng Hui Hsiao, Junjie Li, Marites P. Melancon, Diana S.-L. Chow, Xin Ji, Xiaoxia Wen, Elizabeth M. Whitley, Y. Andrew Wang
Publikováno v:
Cancer Nanotechnology, Vol 11, Iss 1, Pp 1-16 (2020)
Cancer Nanotechnol
Cancer Nanotechnol
Background Doxorubicin-loaded hollow gold nanospheres (Dox@HAuNS) are a promising technology for simultaneous trans-arterial tumor-targeted chemotherapy delivery and thermal ablation. We evaluated the efficacy of intra-arterial delivery of Dox@HAuNS
Autor:
Jason B. Fleming, Ying Ma, Willem W. Overwijk, Chun Li, James A. Bankson, Jun Zhao, Cheng Hui Hsiao, David Piwnica-Worms, Huamin Wang, Anirban Maitra, Qian Huang, Ya'an Kang, Xiaoxia Wen, Diana S.-L. Chow, Stephen E. Ullrich, Eugene J. Koay
Publikováno v:
Biomaterials. 159:215-228
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. It has an excessive desmoplastic stroma that can limit the intratumoral delivery of chemotherapy drugs, and protect tumor cells against radiotherapy. Therefore, both stromal and
Publikováno v:
Biomedical chromatography : BMC. 33(9)
The prominent stromal compartment surrounds pancreatic ductal adenocarcinoma and protects the tumor cells from chemo- or radiotherapy. We hypothesized that our nano formulation carrying cyclopamine (CPA, stroma modulator) and paclitaxel (PTX, antitum
Autor:
Tingting Li, Ying Yuan, Jun Zhao, Huiqin Chen, Willem W. Overwijk, Y. Alan Wang, Chun Li, Zhilan Xiao, Cheng Hui Hsiao, Diana S.-L. Chow
Publikováno v:
ACS nano. 12(10)
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most difficult cancers to treat. It is refractory to most existing therapies, including immunotherapies, due to the presence of an excessive desmoplastic stroma, which restricts penetration o