Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Cheng-Chang Chen"'
Autor:
Barbara Spix, Elisabeth S. Butz, Cheng-Chang Chen, Anna Scotto Rosato, Rachel Tang, Aicha Jeridi, Veronika Kudrina, Eva Plesch, Philipp Wartenberg, Elisabeth Arlt, Daria Briukhovetska, Meshal Ansari, Gizem Günes Günsel, Thomas M. Conlon, Amanda Wyatt, Sandra Wetzel, Daniel Teupser, Lesca M. Holdt, Fabien Ectors, Ingrid Boekhoff, Ulrich Boehm, Jaime García-Añoveros, Paul Saftig, Martin Giera, Sebastian Kobold, Herbert B. Schiller, Susanna Zierler, Thomas Gudermann, Christian Wahl-Schott, Franz Bracher, Ali Önder Yildirim, Martin Biel, Christian Grimm
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Excess macrophage elastase MMP-12 is a major driver of chronic obstructive pulmonary disease. Here the authors show that the endolysosomal ion channel TRPML3 is a regulator of the cellular reuptake of MMP-12, thus neutralizing harmful MMP-12 in the l
Externí odkaz:
https://doaj.org/article/7d029bd581f74fcaa96bcacc1faef5b8
Autor:
Cheng-Chang Chen, Hsiang-Ting Lin, Shih-Pang Chang, Hao-Chung Kuo, Hsiao-Wen Hung, Kuo-Hsiang Chien, Yu-Choung Chang, M. H. Shih
Publikováno v:
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract In this study, we demonstrated large-area high-quality multi-color emission from the 12-fold symmetric GaN photonic quasicrystal nanorod device which was fabricated using the nanoimprint lithography technology and multiple quantum wells regr
Externí odkaz:
https://doaj.org/article/0e25dd714424451bbc74433cc8709775
Autor:
Ponsawan Netcharoensirisuk, Carla Abrahamian, Rachel Tang, Cheng-Chang Chen, Anna Scotto Rosato, Wyatt Beyers, Yu-Kai Chao, Antonio Filippini, Santiago Di Pietro, Karin Bartel, Martin Biel, Angelika M. Vollmar, Kaoru Umehara, Wanchai De-Eknamkul, Christian Grimm
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Two-pore channel 2 (TPC2) resides in endolysosomal membranes but also in lysosome-related organelles such as the melanin producing melanosomes. Gain-of-function polymorphisms in hTPC2 are associated with decreased melanin production and blon
Externí odkaz:
https://doaj.org/article/8f4de751c6ed48b481f4c92a2999702f
Autor:
Yu-Fu Shen, Ming-Chia Wei, Hsin-Pin Li, Yu-Hwa Pan, Hsiang-Hsi Hong, Cheng-Chang Chen, Song-Bor Kuo, Chun-Yeh Ho, Chung-Ta Chang, Yi-Fang Huang
Publikováno v:
Biomedical Journal, Vol 44, Iss 2, Pp 217-222 (2021)
Background: Increasing the vertical dimension of occlusion (VDO) is a common procedure in complicated prosthodontic treatment. The swallowing technique had been verified as a functional method to determine the VDO. The purpose of this study was to in
Externí odkaz:
https://doaj.org/article/abaa42fc975343c394f708c04bc9eed4
Autor:
Cheng-Chang Chen, Einar Krogsaeter, Ching-Ying Kuo, Min-Chuan Huang, Sui-Yuan Chang, Martin Biel
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112751- (2022)
Infectious diseases and cancer are among the key medical challenges that humankind is facing today. A growing amount of evidence suggests that ion channels in the endolysosomal system play a crucial role in the pathology of both groups of diseases. T
Externí odkaz:
https://doaj.org/article/55273c9cde524547a9b6715640c15d2a
Autor:
Sandip Patel, Yu Yuan, Cheng-Chang Chen, Dawid Jaślan, Gihan Gunaratne, Christian Grimm, Taufiq Rahman, Jonathan S. Marchant
Publikováno v:
Cells, Vol 11, Iss 15, p 2368 (2022)
Two-pore channels TPC1 and TPC2 are ubiquitously expressed pathophysiologically relevant proteins that reside on endolysosomal vesicles. Here, we review the electrophysiology of these channels. Direct macroscopic recordings of recombinant TPCs expres
Externí odkaz:
https://doaj.org/article/49fbe1279a6943b6b400febdf218443d
Publikováno v:
Micromachines, Vol 13, Iss 4, p 594 (2022)
An effective System-on-Chip (SoC) for smart Quality-of-Service (QoS) management over a virtual local area network (LAN) is presented in this study. The SoC is implemented by field programmable gate array (FPGA) for accelerating the delivery quality p
Externí odkaz:
https://doaj.org/article/025a825fe6f447a69aa703716b86bb4d
Autor:
Susanne Gerndt, Cheng-Chang Chen, Yu-Kai Chao, Yu Yuan, Sandra Burgstaller, Anna Scotto Rosato, Einar Krogsaeter, Nicole Urban, Katharina Jacob, Ong Nam Phuong Nguyen, Meghan T Miller, Marco Keller, Angelika M Vollmar, Thomas Gudermann, Susanna Zierler, Johann Schredelseker, Michael Schaefer, Martin Biel, Roland Malli, Christian Wahl-Schott, Franz Bracher, Sandip Patel, Christian Grimm
Publikováno v:
eLife, Vol 9 (2020)
Ion selectivity is a defining feature of a given ion channel and is considered immutable. Here we show that ion selectivity of the lysosomal ion channel TPC2, which is hotly debated (Calcraft et al., 2009; Guo et al., 2017; Jha et al., 2014; Ruas et
Externí odkaz:
https://doaj.org/article/64c41b16eef7442a8eaf94088d92df5d
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: In 1883, Ilya Mechnikov discovered phagocytes and established the concept of phagocytosis by macrophages. In 1908, he was awarded the Nobel Prize in Physiology/Medicine for his findings, which laid the foundations for today's understandin
Externí odkaz:
https://doaj.org/article/7e9a1e9bb3ba407cad75cccb243c8415
Autor:
Nicole Bobak, Sylvain Feliciangeli, Cheng-Chang Chen, Ismail Ben Soussia, Stefan Bittner, Sophie Pagnotta, Tobias Ruck, Martin Biel, Christian Wahl-Schott, Christian Grimm, Sven G. Meuth, Florian Lesage
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Recombinant TWIK2 channels produce weak basal background K+ currents. Current amplitudes depend on the animal species the channels have been isolated from and on the heterologous system used for their re-expression. Here we show that this va
Externí odkaz:
https://doaj.org/article/c08363747f7a45328c794c87466f64ca