Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Cheng Zhu Wu"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 829-837 (2019)
New pyrazole with benzo[d]thiazoles containing hydrazinecarboximidamide substituent was synthesised and evaluated for cytotoxicity and apoptotic activity using the MTT assay, flow cytometry, and Western blot analysis. Among the compounds studied, (E)
Externí odkaz:
https://doaj.org/article/c2970beab77f43d19df1c18416f30c01
Autor:
Jie Chen, Long Zhao, Meng-Fan Xu, Di Huang, Xiao-Long Sun, Yu-Xin Zhang, Hong-Mei Li, Cheng-Zhu Wu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractIn this study, seventeen isobavachalcone (IBC) derivatives (1–17) were synthesised, and evaluated for their cytotoxic activity against three human lung cancer cell lines. Among these derivatives, compound 16 displayed the most potent cytoto
Externí odkaz:
https://doaj.org/article/3c2d2bea8c724991b0b42b3b6d0b9c6f
Autor:
Bo-Han Li, Hui Ma, Jing Zhu, Jie Chen, Yi-Qun Dai, Xiao-Jing Zhang, Hong-Mei Li, Cheng-Zhu Wu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this study, 21 new honokiol derivatives were synthesised, and their anti-cancer properties were investigated. Among these, compound 1g exhibited the most potent cytotoxic activity against human nasopharyngeal carcinoma CNE-2Z cells, human gastric
Externí odkaz:
https://doaj.org/article/157fe3a9a7564d00bc536d320a8bdffa
Autor:
Cheng-Zhu Wu, Mei-Jia Gao, Jie Chen, Xiao-Long Sun, Ke-Yi Zhang, Yi-Qun Dai, Tao Ma, Hong-Mei Li, Yu-Xin Zhang
Publikováno v:
Molecules, Vol 27, Iss 20, p 6787 (2022)
Standardized treatment guidelines and effective drugs are not available for human triple-negative breast cancer (TNBC). Many efforts have recently been exerted to investigate the efficacy of natural compounds as anticancer agents owing to their low t
Externí odkaz:
https://doaj.org/article/af41ad30cda348e4bc08eb4056b3cc33
Autor:
Hong-Mei Li, Hui Ma, Xiaolong Sun, Bohan Li, Chengjiang Cao, Yiqun Dai, Meilin Zhu, Cheng-Zhu Wu
Publikováno v:
Molecules, Vol 26, Iss 21, p 6575 (2021)
Ginkgo biloba L. has been used in traditional Chinese medicine (TCM) for thousands of years. However, the anti-cancer properties of ginkgolic acids (GAS) isolated from G. biloba have not been investigated in human nasopharyngeal carcinoma cells. In t
Externí odkaz:
https://doaj.org/article/1df063679ebf4c5bab5e7df5f2421cd2
Autor:
Xiao-Long Sun, Mei-Lin Zhu, Yi-Qun Dai, Hong-Mei Li, Bo-Han Li, Hui Ma, Chang-Hao Zhang, Cheng-Zhu Wu
Publikováno v:
Molecules, Vol 26, Iss 14, p 4302 (2021)
Magnolol (MAG), a biphenolic neolignan, has various biological activities including antitumor effects. In this study, 15 MAG derivatives were semi-synthesized and evaluated for their in vitro anticancer activities. From these derivatives, compound 6a
Externí odkaz:
https://doaj.org/article/cbfc8b6d7c0842f18fd9240170c89762
Autor:
Xiaolong Sun, Jie Chen, Di Huang, Feng Ding, Long Zhao, Hong-Mei Li, Xiang-Shu Wang, Yu-Xin Zhang, Cheng-Zhu Wu
Xanthohumol (Xn) is a chalcone compound isolated from Humulus lupulus Linn. and has various biological activities. In this study, eight Xn derivatives were synthesized by Williamson, Mannich, Reimer-Tiemann, and Schiff base reactions, and five cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a219d148e8193ce04c79cf96cc60652a
https://doi.org/10.21203/rs.3.rs-2761204/v1
https://doi.org/10.21203/rs.3.rs-2761204/v1
Autor:
Yiqun Dai, Xiaolong Sun, Bohan Li, Hui Ma, Pingping Wu, Yingping Zhang, Meilin Zhu, Hong-Mei Li, Minjian Qin, Cheng-Zhu Wu
Publikováno v:
Molecules, Vol 26, Iss 6, p 1604 (2021)
Nasopharyngeal carcinoma (NPC) is a common malignant head and neck tumor. Drug resistance and distant metastasis are the predominant cause of treatment failure in NPC patients. Hispidulin is a flavonoid extracted from the bioassay-guided separation o
Externí odkaz:
https://doaj.org/article/61ca324e165f4a84a4ba95b863f1e96e
Autor:
Lu-Sheng, Wang, Shi-Kun, Zong, Ping-Ping, Wu, Xiao-Long, Sun, Cheng-Zhu, Wu, Hao-Tian, Wang, Mei-Lin, Zhu
Publikováno v:
Journal of Asian natural products research.
ABSTACTA total of 16 fungal strains were isolated from fresh leaves and flowers of
Autor:
Meilin Zhu, Xiaolong Sun, Xiangjian Bai, Cheng-Zhu Wu, Hui Ma, Qiang Huo, Hong-Mei Li, Yiqun Dai, Bohan Li
Publikováno v:
Journal of Bioenergetics and Biomembranes. 52:175-183
Non-small cell lung cancer (NSCLC) constitutes nearly 85% of all cases of lung cancer. Drug resistance, dose-limiting toxicity, and metastasis in NSCLC eventually reduce the efficacy of chemotherapeutics. In this study, we have shown that the methano