Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Cheng Ying Chu"'
Autor:
Shin-Yun Chen, Wei-Ta Chen, Tsorng-Harn Fong, Jiun-Lin Horng, Cheng-Ying Chu, Haojan Yang, Tien-Chun Yang
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e40106- (2024)
This report presents a novel anatomical variant of the second dorsal metacarpal artery (SDMA). In this unique case, the SDMA abnormally penetrates the second dorsal interosseous muscle (SDIM), dividing into two major branches. A deep dorsal branch of
Externí odkaz:
https://doaj.org/article/259ebd3aed96477d88460866e2bcaa1f
Autor:
Chia-Lin Chen, Sheng-Chieh Hsu, Tan-Ya Chung, Cheng-Ying Chu, Hung-Jung Wang, Pei-Wen Hsiao, Shauh-Der Yeh, David K. Ann, Yun Yen, Hsing-Jien Kung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Alterations in metabolism and amino acid usage are common in cancer cells. Here, the authors show in prostate cancer cells that arginine globally upregulates nuclear-encoded oxidative phosphorylation genes by altering histone acetylation and retainin
Externí odkaz:
https://doaj.org/article/d64749011def4c1eae0aaa79e53f01e3
Autor:
Jing-Wen Shih, Wei-Fan Chiang, Alexander T. H. Wu, Ming-Heng Wu, Ling-Yu Wang, Yen-Ling Yu, Yu-Wen Hung, Wen-Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung, Chun A. Changou, Yun Yen, Hsing-Jien Kung
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show
Externí odkaz:
https://doaj.org/article/ff34e185f1024152aa1e6a455b70c21a
Autor:
Po-Chun Chen, Chih-Hsin Tang, Liang-Wei Lin, Chun-Hao Tsai, Cheng-Ying Chu, Tien-Huang Lin, Yuan-Li Huang
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-17 (2017)
Abstract Background Thrombospondin-2 (TSP-2) is a secreted matricellular glycoprotein that is found to mediate cell-to-extracellular matrix attachment and participates in many physiological and pathological processes. The expression profile of TSP-2
Externí odkaz:
https://doaj.org/article/1445e1d3136445ec913f6a39c6126d8d
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Effect of MPT0L145 on autophagosome formation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eefad100bb3432e801a07749d10661
https://doi.org/10.1158/1078-0432.22465095.v1
https://doi.org/10.1158/1078-0432.22465095.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Supplementary Fig. S1, Time-dependent effects of BGJ398 on autophagy in bladder cancer cells. Supplementary Figure. S2. In vitro inhibitory effects of MPT0L145 and SAR405 on PIK3C3 (VPS34). Supplementary Figure. S3. A and B, The potentiation of MPT0L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658cfe700613ef13276cba7e40fe9540
https://doi.org/10.1158/1078-0432.22465083.v1
https://doi.org/10.1158/1078-0432.22465083.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Supplementary Table S1. In vitro inhibitory effects of MPT0L145 on a panel of lipid kinases. Supplementary Table S2. Binding kinetics and affinity of MPT0L145 to wildtype and mutant PIK3C3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad19c396322093c1f2b0450b86e62cbf
https://doi.org/10.1158/1078-0432.22465086.v1
https://doi.org/10.1158/1078-0432.22465086.v1
Autor:
Yun Yen, Jing-Ping Liou, Yun-Ru Liu, Yan-Ni Lo, Yu-Chen Lin, Hao-Ching Wang, Kai-Cheng Hsu, Cheng-Ying Chu, Yu-Ching Lee, Tsung-Han Hsieh, Chun A. Changou, Chun-Han Chen
Purpose: MPT0L145 has been developed as a FGFR inhibitor exhibiting significant anti-bladder cancer activity in vitro and in vivo via promoting autophagy-dependent cell death. Here, we aim to elucidate the underlying mechanisms.Experimental Design: A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec2bd6c4cab8f6c8a53ed80092dc4ae
https://doi.org/10.1158/1078-0432.c.6525918.v1
https://doi.org/10.1158/1078-0432.c.6525918.v1
Autor:
Tzu-Chun, Cheng, John Oliver, Sayseng, Shih-Hsin, Tu, Ting-Ching, Juan, Chia-Lang, Fang, You-Cheng, Liao, Cheng-Ying, Chu, Hui-Wen, Chang, Yun, Yen, Li-Ching, Chen, Yuan-Soon, Ho
Publikováno v:
Journal of Food and Drug Analysis. 29:622-637
This study demonstrated for the first time that curcumin effectively inhibits the growth of triple-negative breast cancer (TNBC) tumors by inhibiting the expression of salt-induced kinase-3 (SIK3) protein in patient-derived xenografted tumor mice (TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b8259a48543968f2e9444321dd9904
https://doi.org/10.38212/2224-6614.3387
https://doi.org/10.38212/2224-6614.3387
Autor:
Cheng-Yu Wang, Chih-Ming Chou, Cheng-Ying Chu, Amy Chen, En-Hsin Liu, Cheng-Yang Liu, Yu-Lin Amy Lee, Fwu-Long Mi, Chia-Hsiung Cheng
Publikováno v:
International journal of biological macromolecules. 224
Low-molecular-weight chitosan (LMWCS) damaged cell membranes in zebrafish showed its possibility to release reporter proteins for detection. In this study, we developed a simple fluorometric-based assay for the evaluation of clinical antiangiogenic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f2593c3b38a17032c20d93033155be
https://pubmed.ncbi.nlm.nih.gov/36306906
https://pubmed.ncbi.nlm.nih.gov/36306906