Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Cheng Kit Wong"'
Autor:
Jamie Trott, Ee Kim Tan, Sheena Ong, Drew M. Titmarsh, Simon L.I.J. Denil, Maybelline Giam, Cheng Kit Wong, Jiaxu Wang, Mohammad Shboul, Michelle Eio, Justin Cooper-White, Simon M. Cool, Giulia Rancati, Lawrence W. Stanton, Bruno Reversade, N. Ray Dunn
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable v
Externí odkaz:
https://doaj.org/article/420b4b50331549cead36ed5ee5db165a
Autor:
Kavya Prasad, Mathew Bloomfield, Hagai Levi, Kristina Keuper, Sara V. Bernhard, Nicolaas C. Baudoin, Gil Leor, Yonatan Eliezer, Maybelline Giam, Cheng Kit Wong, Giulia Rancati, Zuzana Storchová, Daniela Cimini, Uri Ben-David
Publikováno v:
Cancer Res
Aneuploidy is a hallmark of cancer with tissue-specific prevalence patterns that suggest it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on both cellular and genomic conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68879913814bc15d468354095253ac25
https://europepmc.org/articles/PMC9069772/
https://europepmc.org/articles/PMC9069772/
Autor:
Joseph Lee, Ronald Fung, Yu Lin Chong, Altea Targa, Giulia Rancati, Cheng Kit Wong, Katherine E. Larrimore, Hyungwon Choi
Publikováno v:
The EMBO Journal
Adaptive evolution to cellular stress is a process implicated in a wide range of biological and clinical phenomena. Two major routes of adaptation have been identified: non‐genetic changes, which allow expression of different phenotypes in novel en
Autor:
Kristina Keuper, Mathew Bloomfield, Hagai Levi, Prasad K, Nicolaas C. Baudoin, Zuzana Storchova, Cheng Kit Wong, Sara Vanessa Bernhard, Uri Ben-David, Daniela Cimini, Leor G, Maybelline Giam, Giulia Rancati
Aneuploidy – a hallmark of cancer – has tissue-specific recurrence patterns suggesting it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on the cellular and genomic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08cc80b27698fa60462971c7a94cf0d7
https://doi.org/10.1101/2021.05.05.442712
https://doi.org/10.1101/2021.05.05.442712
Autor:
Therese Wilhelm, Hironori Funabiki, Marie Dumont, Ryan R. White, Simona Giunta, Andrea Scelfo, Giulia Rancati, Agata Smogorzewska, Daniele Fachinetti, Riccardo Gamba, Cheng Kit Wong, Solène Hervé
Publikováno v:
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (10), pp.e2015634118. ⟨10.1073/pnas.2015634118⟩
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (10), pp.e2015634118. ⟨10.1073/pnas.2015634118⟩
International audience; Chromosome segregation relies on centromeres, yet their repetitive DNA is often prone to aberrant rearrangements under pathological conditions. Factors that maintain centromere integrity to prevent centromere-associated chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62484b50b2e1358d66f70b1ca739334
http://hdl.handle.net/11573/1606323
http://hdl.handle.net/11573/1606323
Autor:
Simona Giunta, Marie Dumont, Solène Hervé, Ryan R. White, Giulia Rancati, Agata Smogorzewska, Daniele Fachinetti, Therese Wilhelm, Riccardo Gamba, Hironori Funabiki, Andrea Scelfo, Cheng Kit Wong
Chromosome segregation relies on centromeres, yet their repetitive DNA is often prone to aberrant rearrangements under pathological conditions. Factors that maintain centromere integrity to prevent centromere-associated chromosome translocations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050743fab28611b3b8fee3d9fb371771
https://doi.org/10.1101/2020.09.01.277103
https://doi.org/10.1101/2020.09.01.277103
Autor:
Xavier, Bisteau, Joann, Lee, Vinayaka, Srinivas, Joanna H S, Lee, Joanna, Niska-Blakie, Gifford, Tan, Shannon Y X, Yap, Kevin W, Hom, Cheng Kit, Wong, Jeongjun, Chae, Loo Chien, Wang, Jinho, Kim, Giulia, Rancati, Radoslaw M, Sobota, Chris S H, Tan, Philipp, Kaldis
Publikováno v:
Oncogene
Progression through mitosis is balanced by the timely regulation of phosphorylation and dephosphorylation events ensuring the correct segregation of chromosomes before cytokinesis. This balance is regulated by the opposing actions of CDK1 and PP2A, a
Autor:
John E. Connolly, Jiamila Maimaiti, Elaine H. Lim, Karen Crasta, Zhiyan Fu, Kah. J. Lim, Qianqian He, Xiaomeng Wang, Giulia Rancati, Madhura Kulkarni, Bijin Au, Monique N. H. Luijten, Yang Shen, Han Chung Chong, Indrajit Sinha, Cheng Kit Wong
Publikováno v:
Oncogenesis, Vol 7, Iss 8, Pp 1-18 (2018)
Oncogenesis
Oncogenesis
Chromosomal instability (CIN), a high rate of chromosome loss or gain, is often associated with poor prognosis and drug resistance in cancers. Aneuploid, including near-polyploid, cells contain an abnormal number of chromosomes and exhibit CIN. The p
Autor:
Simon M. Cool, Lawrence W. Stanton, Mohammad Shboul, Simon Denil, Drew M. Titmarsh, Giulia Rancati, Justin J. Cooper-White, Ee Kim Tan, Jamie Trott, Sheena Ong, Bruno Reversade, Maybelline Giam, Jiaxu Wang, Michelle Eio, N. Ray Dunn, Cheng Kit Wong
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1675-1688 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit consid
Autor:
Targa, Altea, Larrimore, Katherine E., Cheng Kit Wong, Yu Lin Chong, Fung, Ronald, Lee, Joseph, Hyungwon Choi, Rancati, Giulia
Publikováno v:
EMBO Journal; 11/2/2021, Vol. 40 Issue 21, p1-15, 15p