Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cheng Jung Lai"'
Autor:
Cheng-Jung Lai, Pierre Savagner, Maurizio Voi, Xiong Cai, Wanlu Xu, Abdelkader Selmi, Anna W. Ma, Ruzanna Atoyan, Maria Elena S. Samson, Natalie W. Pursell, Jing Wang
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507edc26f466ad5ba718fef1d735a830
https://doi.org/10.1158/1535-7163.22500235.v1
https://doi.org/10.1158/1535-7163.22500235.v1
Autor:
Cheng-Jung Lai, Pierre Savagner, Maurizio Voi, Xiong Cai, Wanlu Xu, Abdelkader Selmi, Anna W. Ma, Ruzanna Atoyan, Maria Elena S. Samson, Natalie W. Pursell, Jing Wang
PDF file - 178K, Changes in live cell numbers induced by the treatment of CUDC-101, erlotinib, or vorinostat in conditions used in the migration and invasion assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14ccb85c598f6534496be141a7fd5f92
https://doi.org/10.1158/1535-7163.22500238.v1
https://doi.org/10.1158/1535-7163.22500238.v1
Autor:
Cheng-Jung Lai, Pierre Savagner, Maurizio Voi, Xiong Cai, Wanlu Xu, Abdelkader Selmi, Anna W. Ma, Ruzanna Atoyan, Maria Elena S. Samson, Natalie W. Pursell, Jing Wang
PDF file - 28K, Growth inhibitory IC50s of indicated compounds in parental and erlotinib-TR HCC827 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c0e4e6353383c33d0f13df05db68711
https://doi.org/10.1158/1535-7163.22500232
https://doi.org/10.1158/1535-7163.22500232
Autor:
Cheng-Jung Lai, Pierre Savagner, Maurizio Voi, Xiong Cai, Wanlu Xu, Abdelkader Selmi, Anna W. Ma, Ruzanna Atoyan, Maria Elena S. Samson, Natalie W. Pursell, Jing Wang
PDF file - 185K, Growth inhibitory IC50s of indicated compounds in parental and erlotinib-TR HCC827 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1b9a2adaaf67e2291791d608b9c355
https://doi.org/10.1158/1535-7163.22500244.v1
https://doi.org/10.1158/1535-7163.22500244.v1
Autor:
Maurizio Voi, Xiong Cai, Hai-Xiao Zhai, Mylissa Borek, Steven DellaRocca, Anna Wai See Ma, Brian Zifcak, Maria Samson, Ling Yin, Hui Qu, Ruzanna Atoyan, Guang-Xin Xu, Jing Wang, Da-Gong Wang, Rudi Bao, Cheng-Jung Lai, Changgeng Qian
PDF file, 348KB, Figure S1. Synergy between PI3K and HDAC pathway inhibition. Figure S2. CUDC-907 increases acetylation of histone H3 in cultured cancer cells. Figure S3. CUDC-907 increases tubulin acetylation in cultured cancer cells. Figure S4. CUD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32848b021e6bbc17f583b7bdf8d37c66
https://doi.org/10.1158/1078-0432.22445738.v1
https://doi.org/10.1158/1078-0432.22445738.v1
Autor:
Maurizio Voi, Xiong Cai, Hai-Xiao Zhai, Mylissa Borek, Steven DellaRocca, Anna Wai See Ma, Brian Zifcak, Maria Samson, Ling Yin, Hui Qu, Ruzanna Atoyan, Guang-Xin Xu, Jing Wang, Da-Gong Wang, Rudi Bao, Cheng-Jung Lai, Changgeng Qian
Purpose: Given that histone deacetylase (HDAC) inhibitors are known to induce multiple epigenetic modifications affecting signaling networks and act synergistically with phosphatidylinositol 3-kinase (PI3K) inhibitors, we developed a strategy to simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57468279c708b76d5357a1cc33f8026e
https://doi.org/10.1158/1078-0432.c.6520553
https://doi.org/10.1158/1078-0432.c.6520553
Autor:
Steven DellaRocca, Maria Samson, Mitchell Keegan, Rudi Bao, Carmen V. Pepicelli, Dagong Wang, Haixiao Zhai, Guang-Xin Xu, Brian Zifcak, Jing Wang, Cheng-Jung Lai, Changgeng Qian, Xu Tao, Xiong Cai, Ruzanna Atoyan, William E. Munger, Ling Yin, Jeffrey Forrester, Hui Qu
Publikováno v:
Cancer Research. 70:3647-3656
Receptor tyrosine kinase inhibitors have recently become important therapeutics for a variety of cancers. However, due to the heterogeneous and dynamic nature of tumors, the effectiveness of these agents is often hindered by poor response rates and a
Autor:
Guang-Xin Xu, Jeffrey Forrester, Rudi Bao, Dagong Wang, Ling Yin, Maria Samson, Jing Wang, Mylissa Borek, Xu Tao, Brian Zifcak, Changgeng Qian, Hui Qu, Steven DellaRocca, Haixiao Zhai, Xiong Cai, Ruzanna Atoyan, Cheng-Jung Lai
Publikováno v:
Molecular Cancer Therapeutics. 8:3296-3306
CUDC-305 is a heat shock protein 90 (HSP90) inhibitor of the novel imidazopyridine class. Here, we report its activities in non–small cell lung cancer (NSCLC) cell lines with gene deregulations conferring primary or secondary resistance to epiderma
Publikováno v:
Genes to Cells. 10:503-516
Embryonic stem (ES) cells have the capacity to differentiate to every cell type that constitutes fetal or adult tissues. To trace and quantitatively assess the differentiation of ES cells into gut endodermal cells, we used an ES cell line with the la
Publikováno v:
Development. 121:2349-2360
The patterns of embryonic expression and the activities of Xenopus members of the hedgehog gene family are suggestive of roles in neural induction and patterning. We report that these hedgehog polypeptides undergo autoproteolytic cleavage. Injection