Calcitriol Attenuates Doxorubicin-Induced Cardiac Dysfunction and Inhibits Endothelial-to-Mesenchymal Transition in Mice

Autor: Tzu-Hsien Tsai, Cheng-Jei Lin, Chi-Ling Hang, Wei-Yu Chen

Publikováno v: Cells, Vol 8, Iss 8, p 865 (2019)

Doxorubicin (Dox) is an effective anti-neoplasm drug, but its cardiac toxicity limits its clinical use. Endothelial-to-mesenchymal transition (EndMT) has been found to be involved in the process of heart failure. It is unclear whether EndMT contribut

Externí odkaz: https://doaj.org/article/8e20cd5730b242fc9f82df6f6bc3d1bf

Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress

Autor: Tzu-Hsien Tsai, Cheng-Jei Lin, Sarah Chua, Sheng-Ying Chung, Shyh-Ming Chen, Chien-Ho Lee, Chi-Ling Hang

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 10, p 3094 (2018)

Background: Diabetic cardiomyopathy (DCM) is characterized by cardiac fibrosis and stiffness, which often develops into heart failure. This study investigated the role of Ras protein-specific guanine nucleotide releasing factor 1 (RasGRF1) in the dev

Externí odkaz: https://doaj.org/article/e8cde66ac13d4ca891ab17417cb0ca27

Impact of Pharmacist Interventions on the Long-Term Clinical Outcomes in Patients with Myocardial Infarction

Autor: Chun-Chi, Chiou, Tzu-Hsien, Tsai, Chien-Ho, Lee, Cheng-Jei, Lin, Wen-Jung, Chung, Shu-Kai, Hsuch, Po-Jui, Wu, Cheng-I, Cheng

Publikováno v: Acta Cardiologica Sinica. 35(3)

BACKGROUND: Controlling modifiable risk factors (MRFs) in patients with cardiovascular diseases has been shown to be effective in reducing re-hospitalization rates. The aim of this study was to investigate the rates of controlled MRFs and clinical ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f576caff67204af2cf432695c53188c8
https://pubmed.ncbi.nlm.nih.gov/31249459

Diabetes Mellitus: An Independent Risk Factor of In-Hospital Mortality in Patients with Infective Endocarditis in a New Era of Clinical Practice

Autor: Chi-Ling Hang, Sheng-Ying Chung, Cheng-Jei Lin, Sarah Chua, Tzu-Hsien Tsai

Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 16, Iss 12, p 2248 (2019)
Volume 16
Issue 12

Infective endocarditis (IE) is a severe disease with a hospital mortality rate of 17&ndash
25%. Early identification of IE patients with high risk of mortality may improve their clinical outcomes. Patients with diabetes mellitus (DM) who develop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba1416a4021b2eeba08ce80869f5de8
http://europepmc.org/articles/PMC6617149

Prevalence of Hypertension After Living-Donor Liver Transplantation: A Prospective Study

Autor: M.-S. Tong, Shyh-Ming Chen, Cheng-Jei Lin, Wen-Hao Liu, Chi-Ling Hang, Han-Tan Chai, Morgan Fu, Y.-H. Lin, Chao-Long Chen

Publikováno v: Transplantation Proceedings. 47:445-450

Background Hypertension is common among patients who have undergone liver transplantation and is a major contributor to cardiovascular events. Few studies have studied the risk factors associated with post–liver transplantation (LT) hypertension. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ee6bfa1536fc2c7014678eedfc6349
https://doi.org/10.1016/j.transproceed.2014.10.050