Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction

Autor: Anna P. Hnatiuk, Sang‐Ging Ong, Fernanda D. Olea, Paola Locatelli, Johannes Riegler, Won Hee Lee, Cheng Hao Jen, Andrea De Lorenzi, Carlos S. Giménez, Rubén Laguens, Joseph C. Wu, Alberto Crottogini

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)

BackgroundBone marrow mesenchymal stromal cells (BMMSCs) are cardioprotective in acute myocardial infarction (AMI) because of release of paracrine angiogenic and prosurvival factors. Hypoxia‐inducible factor 1‐α (HIF1‐α), rapidly degraded dur

Externí odkaz: https://doaj.org/article/0751544adff642cba976537dc3a450d8

Allogeneic Mesenchymal Stromal Cells Overexpressing Mutant Human Hypoxia‐Inducible Factor 1‐α (HIF1‐α) in an Ovine Model of Acute Myocardial Infarction

Autor: Won Hee Lee, Joseph C. Wu, Anna Hnatiuk, Andrea De Lorenzi, Rubén Laguens, Johannes Riegler, Sang-Ging Ong, Paola Locatelli, Alberto J. Crottogini, Carlos Sebastián Giménez, Cheng Hao Jen, Fernanda Daniela Olea

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Background Bone marrow mesenchymal stromal cells ( BMMSC s) are cardioprotective in acute myocardial infarction ( AMI ) because of release of paracrine angiogenic and prosurvival factors. Hypoxia‐inducible factor 1‐α ( HIF 1‐α), rapidly degra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cccec05a17236a17670e61cbdcd0906
http://europepmc.org/articles/PMC5015403