Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Cheng Han Chung"'
Autor:
Cheng-Han Chung, Christopher M. Murphy, Vincent P. Wingate, Jeffrey W. Pavlicek, Reiko Nakashima, Wei Wei, Douglas McCarty, Joseph Rabinowitz, Erik Barton
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 272-283 (2023)
Recombinant adeno-associated virus (rAAV) is a clinically proven viral vector for delivery of therapeutic genes to treat rare diseases. Improving rAAV manufacturing productivity and vector quality is necessary to meet clinical and commercial demand.
Externí odkaz:
https://doaj.org/article/03d676f6cffd44b1b7b45d8bd0a21868
Autor:
Alexander G. Allen, Cheng-Han Chung, Stephen D. Worrell, Glad Nwaozo, Rebekah Madrid, Anthony R. Mele, Will Dampier, Michael R. Nonnemacher, Brian Wigdahl
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 gene editing system has been shown to be effective at inhibiting human immunodeficiency virus type 1 (HIV-1). Studies have not consistently used a trackable dual reporter sys
Externí odkaz:
https://doaj.org/article/13cdd00f101d4aa9aadb7bcc70933cd5
Autor:
Tea, Kevin, Yuanhao Zu, Cheng Han Chung, Pagliaro, Jaclyn, Espinoza-Barrera, Diana, Mehta, Prakriti, Grewal, Himmat, Douglas, Ivor S., Khan, Yasin A., Shaffer, Jeffrey G., Denson, Joshua L.
Publikováno v:
Critical Care Medicine; Mar2024, Vol. 52 Issue 3, p407-419, 13p
Autor:
Robert W. Link, Diehl R. De Souza, Cassandra Spector, Anthony R. Mele, Cheng-Han Chung, Michael R. Nonnemacher, Brian Wigdahl, Will Dampier
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Accounting for genetic variation is an essential consideration during human immunodeficiency virus type 1 (HIV-1) investigation. Nanopore sequencing preserves proviral integrity by passing long genomic fragments through ionic channels, allowing reads
Externí odkaz:
https://doaj.org/article/b676a6913bc4468e80a81ca26ae87455
Autor:
Cheng-Han Chung, Alexander G. Allen, Andrew J. Atkins, Neil T. Sullivan, Greg Homan, Robert Costello, Rebekah Madrid, Michael R. Nonnemacher, Will Dampier, Brian Wigdahl
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 965-982 (2020)
Viral latency of human immunodeficiency virus type 1 (HIV-1) has become a major hurdle to a cure in the highly effective antiretroviral therapy (ART) era. The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system has successf
Externí odkaz:
https://doaj.org/article/673a12f06876470f8e57428e49edee13
Autor:
Eladio J. Márquez, Cheng-han Chung, Radu Marches, Robert J. Rossi, Djamel Nehar-Belaid, Alper Eroglu, David J. Mellert, George A. Kuchel, Jacques Banchereau, Duygu Ucar
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Whether the immune system aging differs between men and women is barely known. Here the authors characterize gene expression, chromatin state and immune subset composition in the blood of healthy humans 22 to 93 years of age, uncovering shared as wel
Externí odkaz:
https://doaj.org/article/3eccfba4f71b4c47b6e7ca50b74ee79d
Autor:
Andrew Atkins, Cheng-Han Chung, Alexander G. Allen, Will Dampier, Theodore E. Gurrola, Ilker K. Sariyer, Michael R. Nonnemacher, Brian Wigdahl
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
As genome-editing nucleases move toward broader clinical applications, the need to define the limits of their specificity and efficiency increases. A variety of approaches for nuclease cleavage detection have been developed, allowing a full-genome su
Externí odkaz:
https://doaj.org/article/1476ae5fefcf4442bc7e226b35f23b18
Autor:
Cheng-Han Chung, Alexander G. Allen, Andrew Atkins, Robert W. Link, Michael R. Nonnemacher, Will Dampier, Brian Wigdahl
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Clustered regularly interspaced short palindromic repeats (CRISPR)-based HIV-1 genome editing has shown promising outcomes in in vitro and in vivo viral infection models. However, existing HIV-1 sequence variants have been shown to reduce CRISPR-medi
Externí odkaz:
https://doaj.org/article/ea35d33ad04a48eaa63b98608e3704b4
Autor:
Neil T. Sullivan, Alexander G. Allen, Andrew J. Atkins, Cheng-Han Chung, Will Dampier, Michael R. Nonnemacher, Brian Wigdahl
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Human immunodeficiency virus type-1 (HIV-1) infection has resulted in the death of upward of 39 million people since being discovered in the early 1980s. A cure strategy for HIV-1 has eluded scientists, but gene editing technologies such as clustered
Externí odkaz:
https://doaj.org/article/4ed8c20d860c4a08a66dee5068b1c034
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 39 (2021)
Multiporous carbons (MPCs) are prepared using ZnO as a hard template and biomass pyrolysis oil as the carbon source. It is shown that the surface area, pore volume, and mesopore/micropore ratio of the as-prepared MPCs can be easily controlled by adju
Externí odkaz:
https://doaj.org/article/ce90b4a546564dd395c649896670b0d2