Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Cheng Chin Kuo"'
Autor:
Ji Min Park, Yen-Hao Su, Chi-Shuan Fan, Hsin-Hua Chen, Yuan-Kai Qiu, Li-Li Chen, Hsin-An Chen, Thamil Selvee Ramasamy, Jung-Su Chang, Shih-Yi Huang, Wun-Shaing Wayne Chang, Alan Yueh-Luen Lee, Tze-Sing Huang, Cheng-Chin Kuo, Ching-Feng Chiu
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 9, Pp 2065-2081 (2024)
Abstract Ferritin, comprising heavy (FTH1) and light (FTL) chains, is the main iron storage protein, and pancreatic cancer patients exhibit elevated serum ferritin levels. Specifically, higher ferritin levels are correlated with poorer pancreatic duc
Externí odkaz:
https://doaj.org/article/73d02bc8acbd4fc0859f0f58bc89778e
Autor:
Tzu-Ching Chang, Chao-Feng Lin, Yi-Jhu Lu, Shu-Man Liang, Jia-Yi Wei, Chih-Hui Chin, Song-Kun Shyue, Cheng-Chin Kuo, Jun-Yang Liou
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e40026- (2024)
Background: Enhanced angiogenesis following myocardial infarction (MI) is beneficial to preserve cardiac function. The present study aimed to investigate whether acetylated derivatives of cordycepin altered its original antitumor properties and exert
Externí odkaz:
https://doaj.org/article/4982ada29d39434092acea8d36024d36
Autor:
Jih-Kai Huang, Ping-Hsun Wu, Zhao-Feng Chen, Po-Yu Liu, Cheng-Chin Kuo, Yun-Shiuan Chuang, Meng-Zhan Lu, Mei-Chuan Kuo, Yi-Wen Chiu, Yi-Ting Lin
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 623 (2024)
Microbiota tryptophan metabolism and the biosynthesis of indole derivatives play an important role in homeostasis and pathogenesis in the human body and can be affected by the gut microbiota. However, studies on the interplay between gut microbiota a
Externí odkaz:
https://doaj.org/article/a1dd16314acd41d38945f5a1bde89773
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-11 (2022)
Abstract Succinate is a tricarboxylic acid (TCA) cycle intermediate normally confined to the mitochondrial matrix. It is a substrate of succinate dehydrogenase (SDH). Mutation of SDH subunits (SDHD and SDHB) in hereditary tumors such as paraganglioma
Externí odkaz:
https://doaj.org/article/6b3d653c9ac744639216537f3b955b97
Autor:
Yu-Jen Liang, Kuang-Mao Chiang, Li-li Xiu, Chia-Min Chung, Chi-Jen Lo, Ming-Shi Shiao, Mei-Ling Cheng, Cheng-Chin Kuo, Hsin-Chou Yang, Wen-Harn Pan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6458-6466 (2022)
Various groups of antihypertensive drugs targeting different pathways have been developed; however, the pharmacometabolic responses to these drugs have rarely been compared to elucidate the common pathway of blood pressure regulation. Here, we perfor
Externí odkaz:
https://doaj.org/article/995b4d1c5e5144d1adafb7ab991c9815
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Toll-like receptor-2 (TLR2) promotes vascular smooth muscle cell (VSMC) transdifferentiation to chondrocytes and calcification in a p38 MAPK-dependent manner. Vascular 5-methoxytryptophan (5-MTP) is a newly identified factor with
Externí odkaz:
https://doaj.org/article/a55bba9b5f4e4c37833b595349e04928
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 53, Iss 5, Pp 797-802 (2020)
Background: This clinical study investigates the role of 5-methoxytryptophan (5-MTP) in pediatric systemic lupus erythematosus (SLE), with a particular interest in lupus nephritis (LN). Patients and methods: One hundred ten children with SLE were enr
Externí odkaz:
https://doaj.org/article/5ea0d526a194476d99fdfa299ca0d600
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-8 (2020)
Abstract 5-methoxytryptophan (5-MTP) is an endothelial factor with anti-inflammatory properties. It is synthesized from L-tryptophan via two enzymatic steps: tryptophan hydroxylase-1 (TPH-1) and hydroxyindole O-methyltransferase. Lipopolysaccharide (
Externí odkaz:
https://doaj.org/article/9c71dc6d18124b839a62f2b0770ed5ed
Autor:
Meng-Ting Wang, Yun-Han Wang, Hsin-An Chang, Chen-Liang Tsai, Ya-Sung Yang, Chen Wei Lin, Cheng-Chin Kuo, Yu-Juei Hsu
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179472 (2017)
Concerns were raised about pneumonia development from benzodiazepines (BZDs) and Z-drugs, but direct evidence is limited, conflicting and without examining the highly susceptible patients with chronic kidney disease (CKD) nor specifying the risk for
Externí odkaz:
https://doaj.org/article/34efb19f7e1241cfbb7f785d4e4a5955
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152166 (2016)
The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to
Externí odkaz:
https://doaj.org/article/449283d47d514b00a23a420270b779da