Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Chenfeng He"'
Autor:
Ziyang Xu, Cheng Xu, Jie Lu, Chenfeng He, Xinyue Wang, Dongfei Zhu, Aizhong Wang, Zhengyun Zhang, Can Jiang
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102077- (2024)
Cytochrome P450 F3 (CYP4F3) is recognized as a disease-associated immune response initiator that is involved in the synthesis of cholesterol, steroids, and lipids. This study identified the upregulation of CYP4F3 expression in colorectal cancer (CRC)
Externí odkaz:
https://doaj.org/article/701b2620259244759898eb48471e7dc8
Autor:
Wei Li, Kosuke Kawaguchi, Sunao Tanaka, Chenfeng He, Yurina Maeshima, Eiji Suzuki, Masakazu Toi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Several chemotherapeutic drugs induce senescence in cancer cells; however, the mechanisms underlying intracellular pH dysregulation in senescent cells remain unclear. Adenosine triphosphatase H+ transporting accessory protein 2 (ATP6AP2) pla
Externí odkaz:
https://doaj.org/article/f897b5ef2d884c3bb40d11550c3b9eb1
Autor:
Pramod Bharadwaj Chandrashekar, Sayali Alatkar, Jiebiao Wang, Gabriel E. Hoffman, Chenfeng He, Ting Jin, Saniya Khullar, Jaroslav Bendl, John F. Fullard, Panos Roussos, Daifeng Wang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive. With emerging multimodal data for these mechanisms,
Externí odkaz:
https://doaj.org/article/c8c7e6c0ecce42439e257b1b9cc4a68e
Autor:
Alexis Vandenbon, Rin Mizuno, Riyo Konishi, Masaya Onishi, Kyoko Masuda, Yuka Kobayashi, Hiroshi Kawamoto, Ayako Suzuki, Chenfeng He, Yuki Nakamura, Kosuke Kawaguchi, Masakazu Toi, Masahito Shimizu, Yasuhito Tanaka, Yutaka Suzuki, Shinpei Kawaoka
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Spatial transcriptomics reveal how distant cancer affect gene expression and zonation in mouse liver in a manner that differs between biological pathways.
Externí odkaz:
https://doaj.org/article/48608d65ba534a52a3c3a5a77a96a0fd
Autor:
Chirag Gupta, Pramod Chandrashekar, Ting Jin, Chenfeng He, Saniya Khullar, Qiang Chang, Daifeng Wang
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-22 (2022)
Abstract Intellectual and Developmental Disabilities (IDDs), such as Down syndrome, Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth or early childhood. IDDs are characterized by significant impairment in int
Externí odkaz:
https://doaj.org/article/a1166f7da22f46679a4d499170c6bf81
Autor:
Chenfeng He, Noah Cohen Kalafut, Soraya O. Sandoval, Ryan Risgaard, Carissa L. Sirois, Chen Yang, Saniya Khullar, Marin Suzuki, Xiang Huang, Qiang Chang, Xinyu Zhao, Andre M.M. Sousa, Daifeng Wang
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 2, Pp 100409- (2023)
Summary: Our machine-learning framework, brain and organoid manifold alignment (BOMA), first performs a global alignment of developmental gene expression data between brains and organoids. It then applies manifold learning to locally refine the align
Externí odkaz:
https://doaj.org/article/494be02e96414fa5a14749b2ddcb4ea7
Autor:
Chenfeng He, Riyo Konishi, Ayano Harata, Yuki Nakamura, Rin Mizuno, Mayuko Yoda, Masakazu Toi, Kosuke Kawaguchi, Shinpei Kawaoka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancers induce the production of acute phase proteins such as serum amyloid alpha (SAA) in the liver and cause inflammation in various host organs. Despite the well-known coincidence of acute phase response and inflammation, the direct roles of SAA p
Externí odkaz:
https://doaj.org/article/b820b60b7b35439286d7ca025972ba77
Autor:
Chenfeng He, Michael J. Malone, Ben S. Wendel, Ke-Yue Ma, Daniel Del Alcazar, David B. Weiner, Philip L. De Jager, Perla M. Del Río-Estrada, Yuria Ablanedo-Terrazas, Gustavo Reyes-Terán, Laura F. Su, Ning Jiang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Follicular-helper T cells (TFH) are an essential arm of the adaptive immune system. Although TFH were first discovered through their ability to contribute to antibody affinity maturation through co-stimulatory interactions with B cells, new light has
Externí odkaz:
https://doaj.org/article/c4d8069c180c4d2caf8a7868ae973a89
Autor:
Kun Zhu, Chenfeng He, Si-Qi Liu, Mingjuan Qu, Tao Xie, Xiaofeng Yang, Lei Lei, Xiaobo Zhou, Lin Shi, Dan Zhang, Yanbin Cheng, Yae Sun, Huiqiang Zheng, Xiaonan Shen, Qijing Li, Ning Jiang, Baojun Zhang
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Regulatory T cells (Tregs) are essential for the maintenance of gut homeostasis by suppressing conventional CD4+ helper T cells (Tconvs) that are activated by microbial antigens. Although thymus is the major source of the peripheral Tregs, peripheral
Externí odkaz:
https://doaj.org/article/beca8c3b2349411fbe89a838450cf593
Autor:
Ben S. Wendel, Chenfeng He, Mingjuan Qu, Di Wu, Stefany M. Hernandez, Ke-Yue Ma, Eugene W. Liu, Jun Xiao, Peter D. Crompton, Susan K. Pierce, Pengyu Ren, Keke Chen, Ning Jiang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Somatic hypermutation of antibodies can occur in infants but are difficult to track. Here the authors present a new method called MIDCIRS for deep quantitative repertoire sequencing with few cells, and show infants as young as 3 months can expand ant
Externí odkaz:
https://doaj.org/article/e3859fc7336a44ffae74cb5a14acbd04