Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Chenfei Huang"'
Autor:
Chenfei Huang, Yuechao Zhao, Shengchen Lin, Lin Li, Xuan Guo, Sebastian Yumiseba, Jeng-dar Yang, Robert Hariri, Qian Ye, Shuyang He, Adrian Kilcoyne
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Objective Human placenta-derived exosomes (pExo) were generated, characterized, and evaluated as a therapeutic candidate for the treatment of osteoarthritis (OA). Methods pExo was generated from full-term human placenta tissues by sequential
Externí odkaz:
https://doaj.org/article/eb8bbde944544bb08846f4141663cdb5
Autor:
Pooja A. Shah, Chenfei Huang, Qiuli Li, Sawad A. Kazi, Lauren A. Byers, Jing Wang, Faye M. Johnson, Mitchell J. Frederick
Publikováno v:
Cells, Vol 9, Iss 12, p 2677 (2020)
Biomarker-driven targeted therapies are lacking for head and neck squamous cell carcinoma (HNSCC), which is common and lethal. Efforts to develop such therapies are hindered by a genomic landscape dominated by the loss of tumor suppressor function, i
Externí odkaz:
https://doaj.org/article/2c954df22f874164befc85e67bdb08b5
Autor:
Faye M. Johnson, Jing Wang, Jeffery N. Myers, Curtis R. Pickering, Qiuli Li, Chenfei Huang, Tuhina Mazumdar, Ratnakar Singh, Shaohua Peng, Xiayu Rao, Pan Tong, Li Shen, Mitchell J. Frederick, Vaishnavi Sambandam
Figure S8. Effect of the inhibition of multiple components of the PI3K/mTOR pathway in head and neck squamous cell carcinoma (HNSCC) cell lines. A. NOTCH1MUT cells (red text) and NOTCH1WT cells (black text) were treated with increasing concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477fdcfce80ae896df399e696c755052
https://doi.org/10.1158/1078-0432.22469294
https://doi.org/10.1158/1078-0432.22469294
Autor:
Faye M. Johnson, Jing Wang, Jeffery N. Myers, Curtis R. Pickering, Qiuli Li, Chenfei Huang, Tuhina Mazumdar, Ratnakar Singh, Shaohua Peng, Xiayu Rao, Pan Tong, Li Shen, Mitchell J. Frederick, Vaishnavi Sambandam
Table S3. Spearman correlation of protein expression to drug sensitivity based on 70% inhibitory concentration (IC70) or area under the curve (AUC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180cdd98239946a60d2a925f504ae1da
https://doi.org/10.1158/1078-0432.22469282
https://doi.org/10.1158/1078-0432.22469282
Autor:
Faye M. Johnson, Jing Wang, Jeffery N. Myers, Curtis R. Pickering, Qiuli Li, Chenfei Huang, Tuhina Mazumdar, Ratnakar Singh, Shaohua Peng, Xiayu Rao, Pan Tong, Li Shen, Mitchell J. Frederick, Vaishnavi Sambandam
Purpose:Head and neck squamous cell carcinoma (HNSCC) is driven largely by the loss of tumor suppressor genes, including NOTCH1, but lacks a biomarker-driven targeted therapy. Although the PI3K/mTOR pathway is frequently altered in HNSCC, the disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bfe0f2645f526b503fb4865349c43b
https://doi.org/10.1158/1078-0432.c.6527192
https://doi.org/10.1158/1078-0432.c.6527192
Autor:
Deliang Cao, Duan-Fang Liao, William F. Stenson, Mei Chris Huang, Jianghua Liu, Xuyu Zu, Laxiang Wan, Yingchun He, Yu Cao, Yiwen Bu, Chenfei Huang, John Gao, Wancai Yang, Xiaoning Li, Hongyan Ling, Ruilan Yan, Jun Ma, Yi Shen
Purpose: Ulcerative colitis and colitis-associated colorectal cancer (CAC) is a serious health issue, but etiopathological factors remain unclear. Aldo-keto reductase 1B10 (AKR1B10) is specifically expressed in the colonic epithelium, but downregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7aa35704aa330e5e813dbe5e4ddae1
https://doi.org/10.1158/1078-0432.c.6523917
https://doi.org/10.1158/1078-0432.c.6523917
Autor:
Deliang Cao, Duan-Fang Liao, William F. Stenson, Mei Chris Huang, Jianghua Liu, Xuyu Zu, Laxiang Wan, Yingchun He, Yu Cao, Yiwen Bu, Chenfei Huang, John Gao, Wancai Yang, Xiaoning Li, Hongyan Ling, Ruilan Yan, Jun Ma, Yi Shen
Supplemental Figures S1-6, Tables S1-7. Figure S1. Targeted disruption of AKR1B8 gene. Figure S2. AKR1B and AKR1C subfamily expression. Figure S3. Deficiency of proliferation and self-renewal of colonic crypt cells in AKR1B8 -/- mice. Figure S4. DSS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac58dd7208294b177c0224ed74e2203
https://doi.org/10.1158/1078-0432.22458351.v1
https://doi.org/10.1158/1078-0432.22458351.v1
Autor:
Yan Zhao, Junfei Jin, Gao Han, Hongyan Ling, Chenfei Huang, Qianjin Liao, Ping Wu, Jinjun Chen, Xuewen Zhang, Ramina Khoshaba, Min Su, Zhe Cao, Deliang Cao
Publikováno v:
Journal of Cancer
Long non-coding RNAs (lncRNAs) are non-coding RNAs longer than 200 nucleotides that function as regulatory factors in many human diseases, including cancer. However, majority of lncRNAs remain to be characterized. In this study, we characterized a no
Autor:
Junfei Jin, Dan Huang, Deliang Cao, Duan-Fang Liao, Chenfei Huang, Guiyuan Shi, Haitao Ji, Yi Shen, Yiwen Bu, Jun Ma, Zhe Cao, Ramina Khoshaba
Publikováno v:
Molecular Carcinogenesis. 57:1300-1310
Aldo-keto reductase 1B10 (AKR1B10) is upregulated in breast cancer and promotes tumor growth and metastasis. However, little is known of the molecular mechanisms of action. Herein we report that AKR1B10 activates lipid second messengers to stimulate
Autor:
Chun Cai, Chenfei Huang, Yuhong Wang, Dan Huang, Yi Shen, Krishna Rao, Duan-Fang Liao, Junfei Jin, Yiwen Bu, Steven J. Verhulst, Yu Cao, Yingchun He, Deliang Cao
Publikováno v:
Oncotarget
Aldo-keto reductase 1B10 (AKR1B10) is not expressed in normal breast, but upregulated in primary and metastatic breast cancers, being a negative prognostic factor. This study characterized the molecular mechanisms of AKR1B10-promoted breast cancer me