Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Chenera, Balan"'
Autor:
Alan M. Allgeier, Les P. Miranda, Jennifer R. Allen, Vellarkad N. Viswanadhan, Gloria Biddlecome, Randall W. Hungate, Justin K. Murray, Annie Kasparian, Sean Yoder, Chenera Balan, Christopher N. Wilde
Publikováno v:
Journal of Combinatorial Chemistry. 12:676-686
Intracellular levels of the hypoxia-inducible transcription factor (HIF) are regulated under normoxic conditions by prolyl hydroxylases (PHD1, 2, and 3). Treatment of cells with PHD inhibitors stabilizes HIF-1α, eliciting an artificial hypoxic respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841c2c3a4810ce0b6376754f1fdc32f6
https://doi.org/10.1021/cc100073a
https://doi.org/10.1021/cc100073a
Autor:
Charles Bernard, Vijay Keshav Gore, Rami Tamir, Anthony W. Bannon, Hui-Ling Wang, Phi Tang, Sekhar Surapaneni, Jodie Katon, Oliver R. Thiel, Narender R. Gavva, Chenera Balan, Mark H. Norman, Nobuko Nishimura, Celia Dominguez, Vu Van Ma, Elizabeth M. Doherty, James J. S. Treanor
Publikováno v:
Journal of medicinal chemistry. 50(15)
Based on the previously reported clinical candidate, AMG 517 (compound 1), a series of related piperazinylpyrimidine analogues were synthesized and evaluated as antagonists of the vanilloid 1 receptor (VR1 or TRPV1). Optimization of in vitro potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519c2957e1742243aa04fd73fa4aec44
https://pubmed.ncbi.nlm.nih.gov/17585751
https://pubmed.ncbi.nlm.nih.gov/17585751
Autor:
Vellarkad N, Viswanadhan, Chenera, Balan, Christopher, Hulme, Janet C, Cheetham, Yaxiong, Sun
Publikováno v:
Current opinion in drug discoverydevelopment. 5(3)
In the past decade, the pharmaceutical industry has realized the increasing significance of impacting the early phase hit-to-lead development in the drug discovery process. In particular, knowledge-based approaches emerged and evolved to address a mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b57fe28badc32ffa6ff074b72d692961
https://pubmed.ncbi.nlm.nih.gov/12058615
https://pubmed.ncbi.nlm.nih.gov/12058615
Publikováno v:
Cancer Research. 74:1014-1014
Traditional anticancer therapies are limited in their efficacy because they often lead to drug-resistant tumors and display toxicity to normal cells. Control of angiogenesis represents one of the key goals in cancer therapy, as exemplified by targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a23d1c187e084c5a2436af20ebc811
https://doi.org/10.1158/1538-7445.am2014-1014
https://doi.org/10.1158/1538-7445.am2014-1014
Akademický článek
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Autor:
Justin K. Murray1, Chenera Balan1, Alan M. Allgeier1, Annie Kasparian1, Vellarkad Viswanadhan1, Christopher Wilde1, Jennifer R. Allen1, Sean C. Yoder1, Gloria Biddlecome1, Randall W. Hungate1, Les P. Miranda1
Publikováno v:
Journal of Combinatorial Chemistry. Sep2010, Vol. 12 Issue 5, p676-686. 11p.
Autor:
Hui-Ling Wang, Jodie Katon, Chenera Balan, Anthony W. Bannon, Charles Bernard, Elizabeth M. Doherty, Celia Dominguez, Narender R. Gavva, Vijay Gore, Vu Ma, Nobuko Nishimura, Sekhar Surapaneni, Phi Tang, Rami Tamir, Oliver Thiel, James J. S. Treanor, Mark H. Norman
Publikováno v:
Journal of Medicinal Chemistry; Jul2007, Vol. 50 Issue 15, p3528-3539, 12p
Autor:
Newlander, Kenneth A., Chenera, Balan
Publikováno v:
Journal of Organic Chemistry; 10/03/97, Vol. 62 Issue 20, p6726, 7p, 7 Diagrams, 2 Graphs
Autor:
Johnson, William S., Chenera, Balan
Publikováno v:
Journal of the American Chemical Society. 1/27/93, Vol. 115 Issue 2, p493. 5p. 11 Diagrams, 2 Charts.
