Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chenchang Li"'
Publikováno v:
Behavioral Sciences, Vol 13, Iss 7, p 555 (2023)
Affective and cognitive factors play significant roles in influencing students’ learning performance. However, limited studies exist that examine the latent interactions between these factors and students’ learning performance. This study applied
Externí odkaz:
https://doaj.org/article/ebde58b725854b3bb3683360fc476872
Publikováno v:
Behavioral Sciences; Volume 13; Issue 7; Pages: 555
Affective and cognitive factors play significant roles in influencing students’ learning performance. However, limited studies exist that examine the latent interactions between these factors and students’ learning performance. This study applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e2ca8c8fc160d28d0c1fa6779235f1ef
Autor:
Jinsong Liu, Yan Zhang, Xiaoxi Zhuang, Cheng Zhang, Yanli Xing, Yong Xu, Yudan Shi, Jinxin Xu, Chao Wang, Qiu Li, Chenchang Li, Qiuping Xiang, Donghai Wu, Hui Shen, Wu Xishan
Publikováno v:
Journal of Medicinal Chemistry. 64:8775-8797
Receptor-related orphan receptor γ (RORγ) has emerged as an attractive therapeutic target for the treatment of cancer and inflammatory diseases. Herein, we report our effort on the discovery, optimization, and evaluation of benzothiazole and benzim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd1e959ce256ffa76e2169de297c0ac
https://doi.org/10.1021/acs.jmedchem.1c00763
https://doi.org/10.1021/acs.jmedchem.1c00763
Autor:
Jinmao Zou, Lawrence Huang, Lizhao Wang, Yuanyuan Xu, Chenchang Li, Qilin Peng, Hongkui Zeng, Siyu Zhang, Lu Li
Bayesian Brain theory suggests brain utilises predictive processing framework to interpret the noisy world1-11. Predictive processing is essential to perception, action, cognition and psychiatric disease12, but underlying neural circuit mechanisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db2bad5d93cd2604f720ad2599d25f6
https://doi.org/10.1101/2021.12.31.474667
https://doi.org/10.1101/2021.12.31.474667
Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer
Autor:
Yan Zhang, Rui Wang, Qiu Li, Yong Xu, Chenchang Li, Xiaoqian Xue, Shuang Wu, Chao Wang, Yulai Zhou, Lingjiao Zou, Qiuping Xiang, Cheng Zhang
Publikováno v:
Acta Pharmacol Sin
In advanced prostate cancer, CREB (cAMP-responsive element-binding protein) binding protein (CBP) and its homolog EP300 are highly expressed; targeting the bromodomain of CBP is a new strategy for the treatment of prostate cancer. In the current stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195e9eec8c56df9cce1f31744d01f64e
https://doi.org/10.1038/s41401-019-0237-5
https://doi.org/10.1038/s41401-019-0237-5
Autor:
Hongwu Chen, Rui Wang, Qiu Li, Chenchang Li, Junjian Wang, Yan Zhang, Xiaoqian Xue, Lingjiao Zou, Chao Wang, Jinxin Xu, Zenghong Huang, Cheng Zhang, Xiaojuan Hao, Yong Xu, Shi Yudan, Xishan Wu, Donghai Wu, Kerry M. Loomes
Publikováno v:
Journal of Medicinal Chemistry. 62:4716-4730
We report the design, optimization, and biological evaluation of nuclear receptor RORγ inverse agonists as therapeutic agents for prostate cancer treatment. The most potent compound 27 (designated as XY101) exhibited cellular activity with an IC50 v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04de383a335a291b46cc611a0c890368
https://doi.org/10.1021/acs.jmedchem.9b00327
https://doi.org/10.1021/acs.jmedchem.9b00327
Autor:
Yan Zhang, Chun Wu, Adam V. Patterson, Xiaoyan Hui, Ming Song, Yong Xu, Xiaoqian Xue, Jeff B. Smaill, Chao Wang, Kuai Li, Chenchang Li, Cheng Zhang, Ke Ding, Donghai Wu, Yulai Zhou, Qiuping Xiang
Publikováno v:
European Journal of Medicinal Chemistry. 147:238-252
The CREB (cAMP responsive element binding protein) binding protein (CBP) and its homolog EP300 have emerged as new therapeutic targets for the treatment of cancer and inflammatory diseases. Here we report the identification, optimization and evaluati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba40510e8d72598c52e8e2b5e4707e3a
https://doi.org/10.1016/j.ejmech.2018.01.087
https://doi.org/10.1016/j.ejmech.2018.01.087
Publikováno v:
Journal of Energy and Power Technology. :1-1
Due to the uncertainty and volatility of wind speed, its natural output power also exhibits strong volatility. In order to avoid the negative effects of the excessive fluctuation of the output power of wind turbines in the wind farm and the power gri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd20b16a4f8baa0f5d6c0165aebee7fe
https://doi.org/10.21926/jept.2103033
https://doi.org/10.21926/jept.2103033
Autor:
Chun Wu, Y. Zhou, Chenchang Li, Baijun Dong, Wei Xue, Hongwu Chen, Junjian Wang, Chao Wang, Yan Zhang, Qiuping Xiang, Lingjiao Zou, Ming Song, Zhang Maofeng, Xiaoqian Xue, Xishan Wu, Cheng Zhang, Ke Ding, Donghai Wu, Yong Xu
Publikováno v:
Journal of medicinal chemistry. 61(7)
The bromodomain and extra-terminal (BET) family proteins have gained increasing interest as drug targets for treatment of castration-resistant prostate cancer (CRPC). Here, we describe the design, optimization, and evaluation of benzo[d]isoxazole-con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17271221653b7edac7dcbf537fa10c95
https://pubmed.ncbi.nlm.nih.gov/29566488
https://pubmed.ncbi.nlm.nih.gov/29566488