Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chen-Ze Zhao"'
Publikováno v:
World Journal of Clinical Cases. 10:8255-8261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974ea3e8f698714b460f39b2504cf7cf
https://doi.org/10.12998/wjcc.v10.i23.8255
https://doi.org/10.12998/wjcc.v10.i23.8255
Publikováno v:
Cell Biology International. 41:982-990
Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the mevalonate pathway. Our previous studies have indicated that cardiac-specific overexpression of FPPS induces cardiac hypertrophy and dysfunction in mice, and inhibition of FPPS prevents an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c42bcfb529e58e42dfa3550f8802fa
https://doi.org/10.1002/cbin.10795
https://doi.org/10.1002/cbin.10795
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 45:657-666
Farnesyl pyrophosphate synthase (FPPS), as a key branchpoint of the mevalonate pathway, catalyzes the synthesis of isoprenoid intermediates. The isoprenoid intermediates are needed for protein isoprenylation to participate in cardiac remodeling. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a35706010706d64982de75a9496755
https://doi.org/10.1016/j.biocel.2012.12.016
https://doi.org/10.1016/j.biocel.2012.12.016
Autor:
Jie Ding, Chen-Ze Zhao, Yun Mou, Dongpu Dai, Jian Yang, Xu-Ming Zhao, Huan-Dong Wu, Shen-Jiang Hu, Bin Chen
Publikováno v:
Scientific Reports
Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the mevalonate pathway. In our previous studies, we find that inhibition of FPPS attenuates angiotensin II-induced cardiac hypertrophy and fibrosis by suppressing RhoA while FPPS and Ras are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a80fd428967ec78da43a7be3045f0dfc
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2015 (2015)
BioMed Research International, Vol 2015 (2015)
Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e94763d8c0f690233e2f43e49660b8
http://europepmc.org/articles/PMC4320928
http://europepmc.org/articles/PMC4320928
Autor:
Yang Ye, Jian Yang, Chen-Ze Zhao, Yun Mou, Liang Zhou, Chang-Qing Du, Huan-Huan Zhu, Tao Wu, Jun-Chang Jiang, Shen-Jiang Hu
Publikováno v:
Cardiovascular research. 97(3)
Aims Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the mevalonate pathway. In our previous study, we found that inhibition of FPPS attenuates cardiac hypertrophy in spontaneously hypertensive rats (SHRs) and prevents angiotensin (Ang) II-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1b818a0a05ffb66d3b72cfc47414b9
https://pubmed.ncbi.nlm.nih.gov/23180723
https://pubmed.ncbi.nlm.nih.gov/23180723