Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chen-Ming Zeng"'
Autor:
Bo Yang, Qiaojun He, Yong Peng, Yuandong Hu, Xi-Jie Liu, Peihua Luo, Ji Cao, Meidan Ying, Guang-Han Fan, Tianyi Zhou, Ying Chen, Zi-bo Chen, Xiao-Yang Dai, Chen-Ming Zeng, Fang-Jie Yan, Tao Yuan, Dan-Dan Wang, Hong Zhu
Supp Figure 1. The treatment of CT-707 reduced the protein level of CTGF under hypoxia. Supp Figure 2. CT-707 elicited apoptotic cell death but not cell cycle arrest under hypoxia. Supp Figure 3. The protein level of HIF-1α under hypoxia was not inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e9b87d54d6e2ce47863da061697608
https://doi.org/10.1158/0008-5472.22417229
https://doi.org/10.1158/0008-5472.22417229
Autor:
Bo Yang, Qiaojun He, Yong Peng, Yuandong Hu, Xi-Jie Liu, Peihua Luo, Ji Cao, Meidan Ying, Guang-Han Fan, Tianyi Zhou, Ying Chen, Zi-bo Chen, Xiao-Yang Dai, Chen-Ming Zeng, Fang-Jie Yan, Tao Yuan, Dan-Dan Wang, Hong Zhu
Given that Yes-associated protein (YAP) signaling acts as a critical survival input for hypoxic cancer cells in hepatocellular carcinoma (HCC), disruption of YAP function and the maintenance of hypoxia is an attractive way to treat HCC. Utilizing a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dae3c76c27d7e2fea5d6c781ffe1dc
https://doi.org/10.1158/0008-5472.c.6509786
https://doi.org/10.1158/0008-5472.c.6509786
Autor:
Bo Yang, Qiaojun He, Yong Peng, Yuandong Hu, Xi-Jie Liu, Peihua Luo, Ji Cao, Meidan Ying, Guang-Han Fan, Tianyi Zhou, Ying Chen, Zi-bo Chen, Xiao-Yang Dai, Chen-Ming Zeng, Fang-Jie Yan, Tao Yuan, Dan-Dan Wang, Hong Zhu
Materials and Methods for Supplemental Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb7e053fb302d21145cd1fe3b0d2cf9
https://doi.org/10.1158/0008-5472.22417226.v1
https://doi.org/10.1158/0008-5472.22417226.v1
Autor:
Bo Yang, Qiaojun He, Yong Peng, Yuandong Hu, Xi-Jie Liu, Peihua Luo, Ji Cao, Meidan Ying, Guang-Han Fan, Tianyi Zhou, Ying Chen, Zi-bo Chen, Xiao-Yang Dai, Chen-Ming Zeng, Fang-Jie Yan, Tao Yuan, Dan-Dan Wang, Hong Zhu
Supplemental Table 1. The primer sequences for qRT-PCR assay Supplemental Table 2. The targeting sequences for siRNA Supplemental Table 3. The list of compounds for YAP-TEADs luciferase screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34847b6e97939ad8af22b6cd83dfd96f
https://doi.org/10.1158/0008-5472.22417223
https://doi.org/10.1158/0008-5472.22417223
Publikováno v:
Acta Pharmacol Sin
Uveal melanoma (UM) is a rare ocular tumor. The loss of BRCA1-associated protein 1 (BAP1) and the aberrant activation of G protein subunit alpha q (GNAQ)/G protein subunit alpha 11 (GNA11) contribute to the frequent metastasis of UM. Thus far, limite
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 6, Pp 947-960 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Hypoxia is a common feature of solid tumors. As transcription factors, hypoxia-inducible factors (HIFs) are the master regulators of the hypoxic microenvironment; their target genes function in tumorigenesis and tumor development. Intriguingly, both
Autor:
Meidan Ying, Yan Hu, Hong Zhu, Weihua Wang, Chen-Ming Zeng, Lin-Lin Chang, Ji Cao, Bo Yang, Yongchuan Gu, Fujin Ge, Qinxin Zhao, Qiaojun He, Fangjie Yan, Lin Zheng
Publikováno v:
Theranostics
Aldo-keto reductase family 1 member C1 (AKR1C1) promotes malignancy of Non-Small Cell Lung Cancer (NSCLC) by activating Signal Transducer and Activator of Transcription 3 (STAT3) pathway. However, how the pro-metastatic functions of AKR1C1 are switch
Autor:
Qiaojun He, Lin-Lin Chang, Pei-Hua Lu, Chen-Ming Zeng, Chenxi Zhao, Wen-Zhou Zhang, Fujing Ge, Jiamin Du, Hong Zhu, Bo Yang, Yue-Kang Li
Publikováno v:
Acta Pharmacol Sin
Targeting autophagy might be a promising anticancer strategy; however, the dual roles of autophagy in cancer development and malignancy remain unclear. NSCLC (non-small cell lung cancer) cells harbour high levels of SQSTM1 (sequestosome 1), the autop
Autor:
Guang-Han Fan, Chen-Ming Zeng, Hong Zhu, Yuandong Hu, Tao Yuan, Tianyi Zhou, Xi-Jie Liu, Ying Chen, Meidan Ying, Bo Yang, Qiaojun He, Ji Cao, Zi-bo Chen, Peihua Luo, Xiaoyang Dai, Peng Yong, Fangjie Yan, Dandan Wang
Publikováno v:
Cancer Research. 78:3995-4006
Given that Yes-associated protein (YAP) signaling acts as a critical survival input for hypoxic cancer cells in hepatocellular carcinoma (HCC), disruption of YAP function and the maintenance of hypoxia is an attractive way to treat HCC. Utilizing a c
Autor:
Tao Yuan, Ying Hu, Bo Yang, Qiaojun He, Fangjie Yan, Lin-Lin Chang, Ying, Hong Zhu, Tianyi Zhou, Chen-Ming Zeng, Ji Cao
Publikováno v:
Theranostics
Metastasis is the leading cause of mortality for human non-small cell lung cancer (NSCLC). However, it is difficult to target tumor metastasis because the molecular mechanisms underlying NSCLC invasion and migration remain unclear. Methods: GEO data