Výsledky vyhledávání - "Chen-Ming Tan"

Dissertation/ Thesis

Autor: Chen-Ming Tan, 譚誠明

90
Hydrophilic metal ions can be extracted from aqua by organic solvent with proper organic chelating agent. Nevertheless, a new problem comes from the great volume of organic solvent containing metal ions. Supercritical fluids can replace conve

Externí odkaz: http://ndltd.ncl.edu.tw/handle/54108985467488259266

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Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors

Autor: Chen-Ming Tan, Grace Shiahuy Chen, Chien Shu Chen, Ji-Wang Chern, Pei-Teh Chang

Publikováno v: Bioorganic & Medicinal Chemistry. 19:6316-6328

3-(4-Bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide (5) was discovered as a new prototype for dual inhibitors of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). Thus, the structure–activity relationships of benzo[1.3.2]dithiazo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab4b67637852b84a83f3fe0a90faa73
https://doi.org/10.1016/j.bmc.2011.09.003

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Microwave-Assisted Cross-Coupling for the Construction of Diaryl Sulfides

Autor: Chien Shu Chen, Chen-Ming Tan, Grace Shiahuy Chen, Ji-Wang Chern

Publikováno v: Journal of the Chinese Chemical Society. 58:94-100

The construction of diaryl sulfides through the cross-coupling of aryl iodides and thiols in microwave heating is described. By using this method, a variety of diaryl sulfides can be prepared in a mild condition and in high yields. Deactivated 4-nitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c2510dd439eff8ad291288d6250e4be
https://doi.org/10.1002/jccs.201190064

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Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-α production

Autor: Jih-Pyang Wang, Chien Shu Chen, Fong-Chi Cheng, Chiung-Hua Huang, Chen-Ming Tan, Ji-Wang Chern, Ling-Chu Chang

Publikováno v: Bioorganic & Medicinal Chemistry. 18:597-604

In the present study we have discovered compound 1 , a benzo[1.3.2]dithiazolium ylide-based compound, as a new prototype dual inhibitor of cyclooxygenase (COX) and 5-lipoxygenase (5-LOX). Compound 1 was initially discovered as a COX-2 inhibitor, resu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4dea842e8a75f5a54491bdff1dbd29
https://doi.org/10.1016/j.bmc.2009.12.008

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