Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Chen-Meng Qiao"'
Autor:
Mei-Xuan Zhang, Hui Hong, Yun Shi, Wen-Yan Huang, Yi-Meng Xia, Lu-Lu Tan, Wei-Jiang Zhao, Chen-Meng Qiao, Jian Wu, Li-Ping Zhao, Shu-Bing Huang, Xue-Bing Jia, Yan-Qin Shen, Chun Cui
Publikováno v:
Brain Sciences, Vol 14, Iss 4, p 300 (2024)
Parkinson’s disease (PD) is characterized not only by motor symptoms but also by non-motor dysfunctions, such as olfactory impairment; the cause is not fully understood. Our study suggests that neuronal loss and inflammation in brain regions along
Externí odkaz:
https://doaj.org/article/b97a6b45c17c450a817bf7274fd593d1
Autor:
Chen-Meng Qiao, Wen-Yan Huang, Yu Zhou, Wei Quan, Gu-Yu Niu, Ting Li, Mei-Xuan Zhang, Jian Wu, Li-Ping Zhao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 238 (2024)
Increasing evidence suggests that the gut microbiota may represent potential strategies for Parkinson’s disease (PD) treatment. Our previous research revealed a decreased abundance of Akkermansia muciniphila (Akk) in PD mice; however, whether Akk i
Externí odkaz:
https://doaj.org/article/770f2fcdb0064653b87c47e0372a4742
Autor:
Li-Ping Zhao, Jian Wu, Wei Quan, Yu Zhou, Hui Hong, Gu-Yu Niu, Ting Li, Shu-Bing Huang, Chen-Meng Qiao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Accumulative studies suggest that inflammatory bowel disease (IBD) may cause multiple central nervous system (CNS) pathologies. Studies have found that indoleamine-2,3-dioxygenase (IDO, rate-limiting enzyme of the kynurenine (Kyn) pathway) deficient
Externí odkaz:
https://doaj.org/article/5f29231e6cb143bebf7ecd53f2cd091b
Autor:
Xin-yu Qiao, Yi Wang, Wei Zhang, Qian Li, Chong Liu, Ji-ji Dao, Chen-meng Qiao, Chun Cui, Yan-qin Shen, Wei-jiang Zhao
Publikováno v:
Journal of Integrative Neuroscience, Vol 22, Iss 4, p 96 (2023)
Objective: Few studies have reported the direct effect of C–X–C motif chemokine ligand 10 (CXCL10) and Neuregulin 1 (Nrg1) on neurons after spinal cord injury (SCI). This study reports the role of CXCL10 in the regulation of neuronal damage after
Externí odkaz:
https://doaj.org/article/457bfb7a80d64776844c23eb4bce8c8e
Autor:
Wei Quan, Chen-Meng Qiao, Gu-Yu Niu, Jian Wu, Li-Ping Zhao, Chun Cui, Wei-Jiang Zhao, Yan-Qin Shen
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 790 (2023)
Observational studies have shown abnormal changes in trimethylamine N-oxide (TMAO) levels in the peripheral circulatory system of Parkinson’s disease (PD) patients. TMAO is a gut microbiota metabolite that can cross the blood–brain barrier and is
Externí odkaz:
https://doaj.org/article/960e3ffb27584aa4960d43ae4274541c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundTransient receptor potential melastatin 8 (TRPM8) modulates tumor biology and sensitivity to treatment. The present study aimed to determine the part it plays in tumor immunity and physiology using pan-cancer analysis.MethodData from the GT
Externí odkaz:
https://doaj.org/article/a90d9dd09c184c3b9596d909f1b246e1
Autor:
Li-Ping Zhao, Jian Wu, Wei Quan, Yu Zhou, Hui Hong, Gu-Yu Niu, null Ting-Li, Shu-Bing Huang, Chen-Meng Qiao, Wei-Jiang Zhao, Chun Cui, Yan-Qin Shen
Publikováno v:
The Journal of Nutritional Biochemistry. 115:109282
Autor:
Xue-Bing Jia, Chen-Meng Qiao, Yu Zhou, Wei-Jiang Zhao, Li Yao, Yan-Qin Shen, Hui Hong, Shu-Bing Huang, Yun Shi, Chun Cui, Ji Wu
Publikováno v:
Biochemical and Biophysical Research Communications. 556:16-22
Evidence suggests constipation precedes motor dysfunction and is the most common gastrointestinal symptom in Parkinson's disease (PD). 5-HT4 receptor (5-HT4R) agonist prucalopride has been approved to treat chronic constipation. Here, we reported int
Autor:
Shu-Bing Huang, Chun Cui, Yun Shi, Li-Ping Zhao, Xue-Bing Jia, Bo-Ping Zhang, Zhi-Lan Zhou, Fang Wang, Meng-Fei Sun, Li Yao, Yan-Qin Shen, Chen-Meng Qiao
Publikováno v:
Cellular and Molecular Neurobiology. 42:1373-1384
Insulin-like growth factor-1 (IGF-1) is a neurotrophic factor produced locally in the central nervous system which can promote axonal regeneration, protect motoneurons, and inhibit neuroinflammation. In this study, we used the zebrafish spinal transe
Autor:
Chun Cui, Yang Li, Meng-Fei Sun, Zhi-Lan Zhou, Ying-Li Zhu, Chen-Meng Qiao, Yun Shi, Li-Ping Zhao, Yan-Qin Shen, Bo-Ping Zhang, Xue-Bing Jia
Publikováno v:
Neurochemical Research. 45:2128-2142
The abnormal production of short chain fatty acid (SCFAs) caused by gut microbial dysbiosis plays an important role in the pathogenesis and progression of Parkinson’s disease (PD). This study sought to evaluate how butyrate, one of SCFAs, affect th