Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Chen-Jun Guo"'
Autor:
Guang-Ming Lu, Huan-Huan Hu, Chia-Chun Chang, Jiale Zhong, Xian Zhou, Chen-Jun Guo, Tianyi Zhang, Yi-Lan Li, Boqi Yin, Ji-Long Liu
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background PRPP synthase (PRPS) transfers the pyrophosphate groups from ATP to ribose-5-phosphate to produce 5-phosphate ribose-1-pyrophosphate (PRPP), a key intermediate in the biosynthesis of several metabolites including nucleotides, dinu
Externí odkaz:
https://doaj.org/article/7f27df0d7dd448b29cad47f0feae8a41
Publikováno v:
Guoji Yanke Zazhi, Vol 22, Iss 7, Pp 1228-1233 (2022)
AIM: To investigate the choice of surgical approach, therapeutic effect and complications of orbital cavernous hemangioma(OCH)in different positions of orbit.METHODS: The clinical data of 128 patients of 128 eyes with OCH whose were surgically remove
Externí odkaz:
https://doaj.org/article/2252a67d82874511971362b4083ac37c
Autor:
Huan-Huan Hu, Guang-Ming Lu, Chia-Chun Chang, Yilan Li, Jiale Zhong, Chen-Jun Guo, Xian Zhou, Boqi Yin, Tianyi Zhang, Ji-Long Liu
Publikováno v:
eLife, Vol 11 (2022)
Phosphoribosyl pyrophosphate (PRPP) is a key intermediate in the biosynthesis of purine and pyrimidine nucleotides, histidine, tryptophan, and cofactors NAD and NADP. Abnormal regulation of PRPP synthase (PRPS) is associated with human disorders, inc
Externí odkaz:
https://doaj.org/article/46c77353daa547c5963b470113dda424
Autor:
Jiale Zhong, Chen-Jun Guo, Xian Zhou, Chia-Chun Chang, Boqi Yin, Tianyi Zhang, Huan-Huan Hu, Guang-Ming Lu, Ji-Long Liu
Publikováno v:
eLife, Vol 11 (2022)
The bifunctional enzyme Δ1-pyrroline-5-carboxylate synthase (P5CS) is vital to the synthesis of proline and ornithine, playing an essential role in human health and agriculture. Pathogenic mutations in the P5CS gene (ALDH18A1) lead to neurocutaneous
Externí odkaz:
https://doaj.org/article/4919bfad814545dfb6cfce7ab23adc0d
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 647 (2022)
Cytidine-5′-triphosphate (CTP) synthase (CTPS) is the class I glutamine-dependent amidotransferase (GAT) that catalyzes the last step in the de novo biosynthesis of CTP. Glutamine hydrolysis is catalyzed in the GAT domain and the liberated ammonia
Externí odkaz:
https://doaj.org/article/07c72d2792134f00a863e683af8f6b75
Autor:
Chang-Geng Song, Yi-Zhe Zhang, Hai-Ning Wu, Xiu-Li Cao, Chen-Jun Guo, Yong-Qiang Li, Min-Hua Zheng, Hua Han
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 7, Pp 1294-1304 (2018)
Neurologic impairments are usually irreversible as a result of limited regeneration in the central nervous system. Therefore, based on the regenerative capacity of stem cells, transplantation therapies of various stem cells have been tested in basic
Externí odkaz:
https://doaj.org/article/56012afb1ef8489c8f4a29cb9150d909
Autor:
Fang Gao, Yu-Fei Zhang, Zheng-Ping Zhang, Luo-An Fu, Xiu-Li Cao, Yi-Zhe Zhang, Chen-Jun Guo, Xian-Chun Yan, Qin-Chuan Yang, Yi-Yang Hu, Xiang-Hui Zhao, Ya-Zhou Wang, Sheng-Xi Wu, Gong Ju, Min-Hua Zheng, Hua Han
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1032-1045 (2017)
Summary: Notch signaling is critically involved in neural development, but the downstream effectors remain incompletely understood. In this study, we cultured neurospheres from Nestin-Cre-mediated conditional Rbp-j knockout (Rbp-j cKO) and control em
Externí odkaz:
https://doaj.org/article/71dd106965c14f438f70175d16c22a66
Autor:
Chen Jun Guo, Xiu Li Cao, Yu Fei Zhang, Kang Yi Yue, Jing Han, Hong Yan, Hua Han, Min Hua Zheng
Publikováno v:
Molecular Therapy - Nucleic Acids. 31:763-778
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85b331a0d3c2a67413864d17eed6735f
https://doi.org/10.1016/j.omtn.2023.02.015
https://doi.org/10.1016/j.omtn.2023.02.015
Glutaminase is a rate-limiting enzyme in glutaminolysis, which produces glutamate from glutamine and enters the TCA cycle[1]. In addition, it plays a key role in redox homeostasis[2], autophagy[3], immune system regulation[4], central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2df8e62c9cb69d264890ae0fad8f0afd
https://doi.org/10.1101/2023.03.30.534948
https://doi.org/10.1101/2023.03.30.534948
Autor:
He, De-Gao, Chen, Xi-Jie, Huang, Juan-Ni, Chen, Jun-Guo, Lv, Min-Yi, Huang, Tian-Ze, Lan, Ping, He, Xiao-Sheng
Publikováno v:
World Journal of Gastrointestinal Oncology
BACKGROUND Inflammatory bowel disease (IBD) patients with post-inflammatory polyps (PIPs) may carry an increased risk of colorectal neoplasia (CRN) including dysplasia and cancer. Current guidelines recommend active colonoscopy follow-up for these pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119079b427a0c018479b603d863b4f9c
https://doi.org/10.4251/wjgo.v14.i1.348
https://doi.org/10.4251/wjgo.v14.i1.348