Výsledky vyhledávání - "Chen-Hsiung Yeh"

Akademický článek

Neutral sphingomyelinase activation in endothelial and glial cell death induced by amyloid beta-peptide

Autor: Ding-I Yang, Chen-Hsiung Yeh, Shawei Chen, Jan Xu, Chung Y. Hsu

Publikováno v: Neurobiology of Disease, Vol 17, Iss 1, Pp 99-107 (2004)

We have explored the molecular mechanism underlying amyloid beta-peptide (Aβ)-mediated cytotoxicity in vitro. Exposure of murine cerebral endothelial cells (CECs) or C6 glioma cells to Aβ25-35 resulted in dose-dependent cell death. Ceramide is a pr

Externí odkaz: https://doaj.org/article/f18b6d53f21a4b97b6e78389867c913b

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Akademický článek

Enhancement of Outward Potassium Current May Participate in β-Amyloid Peptide-Induced Cortical Neuronal Death

Autor: Shan Ping Yu, Z.Shadi Farhangrazi, Howard S. Ying, Chen-Hsiung Yeh, Dennis W. Choi

Publikováno v: Neurobiology of Disease, Vol 5, Iss 2, Pp 81-88 (1998)

In light of recent evidence implicating the upregulation of outward K+current in mediating several forms of neuronal apoptosis, we tested the hypothesis that such an upregulation might specifically contribute to the pathogenesis of β-amyloid peptide

Externí odkaz: https://doaj.org/article/ab22b871dd70461a99eb2f505182f3fe

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Akademický článek

Effects of clinically relevant MPL mutations in the transmembrane domain revealed at the atomic level through computational modeling.

Autor: Tai-Sung Lee, Hagop Kantarjian, Wanlong Ma, Chen-Hsiung Yeh, Francis Giles, Maher Albitar

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23396 (2011)

BACKGROUND: Mutations in the thrombopoietin receptor (MPL) may activate relevant pathways and lead to chronic myeloproliferative neoplasms (MPNs). The mechanisms of MPL activation remain elusive because of a lack of experimental structures. Modern co

Externí odkaz: https://doaj.org/article/db676c08a8f9402dbf0ab5a9fec002e7

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Akademický článek

JAK2 exon 14 deletion in patients with chronic myeloproliferative neoplasms.

Autor: Wanlong Ma, Hagop Kantarjian, Xi Zhang, Xiuqiang Wang, Zhong Zhang, Chen-Hsiung Yeh, Susan O'Brien, Francis Giles, Jean Marie Bruey, Maher Albitar

Publikováno v: PLoS ONE, Vol 5, Iss 8, p e12165 (2010)

BACKGROUND: The JAK2 V617F mutation in exon 14 is the most common mutation in chronic myeloproliferative neoplasms (MPNs); deletion of the entire exon 14 is rarely detected. In our previous study of >10,000 samples from patients with suspected MPNs t

Externí odkaz: https://doaj.org/article/ab401484d9064add8d0cd69ffcb13c35

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Akademický článek

Detection, analysis and clinical validation of chromosomal aberrations by multiplex ligation-dependent probe amplification in chronic leukemia.

Autor: Adam Abdool, Amber C Donahue, Jay G Wohlgemuth, Chen-Hsiung Yeh

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e15407 (2010)

Current diagnostic screening strategies based on karyotyping or fluorescent in situ hybridization (FISH) for detection of chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are laborious, time-consuming, costly, and have limitations in r

Externí odkaz: https://doaj.org/article/71f4e9af01454d34844d83075eb1c907

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Dissertation/ Thesis

The key success factors of micro-enterprises in Taiwan _ a coffee ice cream shop in Kaohsiung as an example

Autor: Chen-Hsiung Yeh, 葉振雄

98
As Taiwan government has been actively expanding the liberalization of trade tariffs (as recently the ECFA or FTA), the SMEs ( Small and Medium Enterprises ) in Taiwan are facing pressure from global competitions, and the financial turmoil i

Externí odkaz: http://ndltd.ncl.edu.tw/handle/77958291028929244370

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Enabling circulating cell-free mRNA theranostics from PD-L1, ALK, ROS1, NTRK to transcriptomic profiling

Autor: Chen-Hsiung Yeh

Publikováno v: Journal of Clinical Oncology. 40:3033-3033

3033 Background: Circulating cell-free mRNA (cfmRNA) expression can be considered as a compendium of transcripts collected from all organs. It has the capability of integrating functional and genetic information of tissues, highlighting this analyte�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1433c5e43004d8640e6c29dbd97bad8
https://doi.org/10.1200/jco.2022.40.16_suppl.3033

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