Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chen Sok Lam"'
Publikováno v:
Developmental Dynamics. 238:475-486
Adult neurogenesis arises from niches that harbor neural stem cells (NSC). Although holding great promise for regenerative medicine, the identity of NSC remains elusive. In mammals, a key attribute of NSC is the expression of the filamentous proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef44a554582487d55e899f9d2b3e8ba4
https://doi.org/10.1002/dvdy.21853
https://doi.org/10.1002/dvdy.21853
Publikováno v:
Molecular and Cellular Neuroscience. 22:501-515
Several signaling pathways have been implicated in the development of dopaminergic and serotonergic neurons. Here, we analyzed the formation of noradrenergic (NAergic) cells in the locus coeruleus (LC) of zebrafish. In the sonic hedgehog (shh) mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae11117a7a943f522529bbc009fbc66
https://doi.org/10.1016/s1044-7431(03)00031-9
https://doi.org/10.1016/s1044-7431(03)00031-9
Autor:
Thorsten Wohland, Tapan Kumar Mistri, Chen Sok Lam, L. Lim, Hui Theng Gan, Yong Hwee Foo, David Rodda, Thankiah Sudhaharan, Sohail Ahmed, Chai Chou, Paul Robson
Publikováno v:
The Biochemical journal. 448(1)
Oct4 and Sox2 are two essential transcription factors that co-regulate target genes for the maintenance of pluripotency. However, it is unclear whether they interact prior to DNA binding or how the target sites are accessed in the nucleus. By generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7997e2b58bbd47f01966e9a31935f1bd
https://pubmed.ncbi.nlm.nih.gov/22909387
https://pubmed.ncbi.nlm.nih.gov/22909387
Publikováno v:
Embryonic Stem Cells-Differentiation and Pluripotent Alternatives
Human embryonic stem cells (hESCs) were first established as an in vitro culture system (Thomson et al., 1998). hESCs are pluripotent cells that are able to self-renew and can differentiate into the three primary germ layers: endoderm, ectoderm and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef27b01811071582c12c8d8c14b508c6
https://doi.org/10.5772/24489
https://doi.org/10.5772/24489
Autor:
Colette Vaillant, Martin März, Birgit Hesl, Nicolas Diotel, Chen Sok Lam, Laure Bally-Cuif, Uwe Strähle, Olivier Kah, Masanari Takamiya, Prisca Chapouton
Publikováno v:
Glia
Glia, Wiley, 2010, 58 (7), pp.870-88. ⟨10.1002/glia.20971⟩
Glia, 2010, 58 (7), pp.870-88. ⟨10.1002/glia.20971⟩
Glia, Wiley, 2010, 58 (7), pp.870-88. ⟨10.1002/glia.20971⟩
Glia, 2010, 58 (7), pp.870-88. ⟨10.1002/glia.20971⟩
International audience; The zebrafish has become a new model for adult neurogenesis, owing to its abundant neurogenic areas in most brain subdivisions. Radial glia-like cells, actively proliferating cells, and label-retaining progenitors have been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e13eb389e5c42d9fa0e5493d3ab80f
https://hal.archives-ouvertes.fr/hal-00477506
https://hal.archives-ouvertes.fr/hal-00477506
Autor:
Anuradha Poonepalli, Yuan Hong Yu, Chen Sok Lam, Muly Tham, Yvonne Tay, Srinivas Ramasamy, Sohail Ahmed, Hui Theng Gan
Publikováno v:
Cell adhesionmigration. 3(4)
The central nervous system (CNS) is a large network of interconnecting and intercommunicating cells that form functional circuits. Disease and injury of the CNS are prominent features of the healthcare landscape. There is an urgent unmet need to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0472d390ddb06cae54952bbbcccb60
https://pubmed.ncbi.nlm.nih.gov/19535895
https://pubmed.ncbi.nlm.nih.gov/19535895
Autor:
Laure Bally-Cuif, Stefanie Topp, Uwe Strähle, Chen Sok Lam, Birgit Adolf, Prisca Chapouton, Magdalena Götz, Birgit Tannhäuser
Publikováno v:
Dev. Biol. 295, 278-293 (2006)
Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cell state remains fragmentary. To provide new models on this issue, we searched for stem cells in the adult brain of the zebrafish. Using BrdU tracing and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4fbb4f59c9525ce7ffdc4ec0c9796d9
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=5244
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=5244
Publikováno v:
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2005, 21 (6), pp.1758-62. ⟨10.1111/j.1460-9568.2005.03988.x⟩
European Journal of Neuroscience, Wiley, 2005, 21 (6), pp.1758-62. ⟨10.1111/j.1460-9568.2005.03988.x⟩
International audience; The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces selective loss of dopaminergic neurons in the mammalian midbrain, eliciting symptoms characteristic of Parkinson's disease. By exploiting the advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdea17dfe896dad09d0740cdf33f2616
https://hal.archives-ouvertes.fr/hal-00187654
https://hal.archives-ouvertes.fr/hal-00187654
Autor:
Jean-Christophe Nicod, Charles Plessy, Nicolas Simplicio, Carol Schuurmans, François Guillemot, Raffaella Scardigli, Chen Sok Lam, Patrick Blader, Sepand Rastegar, Nadine Fischer, Uwe Strähle
Publikováno v:
Development (Cambridge, England). 131(22)
The telencephalon shows vast morphological variations among different vertebrate groups. The transcription factor neurogenin1(ngn1) controls neurogenesis in the mouse pallium and is also expressed in the dorsal telencephalon of the evolutionary dista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab761ce91ea2cf749f19b7ae2957bd4c
https://pubmed.ncbi.nlm.nih.gov/15496438
https://pubmed.ncbi.nlm.nih.gov/15496438
Publikováno v:
Trends in genetics : TIG. 20(3)
Situated at the ventral-most part of the vertebrate neural tube, the floor plate (FP) is an important signalling centre that controls the regional differentiation of neurons in the nervous system. It secretes guidance molecules that direct ventrally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c22530068913713d459f6ce7d7d0e48
https://pubmed.ncbi.nlm.nih.gov/15036809
https://pubmed.ncbi.nlm.nih.gov/15036809